Table of Contents

Original articles

• Primary ciliary dyskinesia

  • Open Access

    Pulmonary exacerbations in patients with primary ciliary dyskinesia: an expert consensus definition for use in clinical trials

    Jane S. Lucas, Florian Gahleitner, Adelina Amorim, Mieke Boon, Philippa Brown, Carolina Constant, Simon Cook, Suzanne Crowley, Damien M.S. Destouches, Ernst Eber, Huda Mussaffi, Eric Haarman, Amanda Harris, Cordula Koerner-Rettberg, Claudia E. Kuehni, Philipp Latzin, Michael R. Loebinger, Natalie Lorent, Bernard Maitre, Antonio Moreno-Galdó, Kim G. Nielsen, Uğur Özçelik, Lue Katrine Drasbæk Philipsen, Petr Pohunek, Eva Polverino, Jessica Rademacher, Phil Robinson, Deborah Snijders, Panayiotis Yiallouros, Siobhán B. Carr

    ERJ Open Res 5: 00147-2018; DOI: 10.1183/23120541.00147-2018 Published 1 February 2019

• Asthma

  • Open Access

    Pharmacological treatment of asthma in a cohort of adults during a 20-year period: results from the European Community Respiratory Health Survey I, II and III

    Christer Janson, Simone Accordini, Lucia Cazzoletti, Isa Cerveri, Sebastien Chanoine, Angelo Corsico, Diogenes Seraphim Ferreira, Judith Garcia-Aymerich, David Gislason, Rune Nielsen, Ane Johannessen, Rain Jogi, Andrei Malinovschi, Jesús Martinez-Moratalla Rovira, Alessandro Marcon, Isabelle Pin, Jennifer Quint, Valerie Siroux, Enrique Almar, Valeria Bellisario, Karl A. Franklin, José A. Gullón, Mathias Holm, Joachim Heinrich, Dennis Nowak, José Luis Sánchez-Ramos, Joost J. Weyler, Deborah Jarvis

    ERJ Open Res 5: 00073-2018; DOI: 10.1183/23120541.00073-2018 Published 1 February 2019
  • Open Access

    How does the GINA definition of control correlate with quality of life and sputum cellularity?

    Marcia Margaret Menezes Pizzichini, Cristiane Cinara Rocha, Michelle Gonçalves de Souza Tavares, Leila John Marques Steidle, Rosemeri Maureci da Silva, Felipe dal Pizzol, Peter G. Gibson, Emilio Pizzichini

    ERJ Open Res 5: 00146-2018; DOI: 10.1183/23120541.00146-2018 Published 4 February 2019
  • Open Access

    Airway transcriptomic profiling after bronchial thermoplasty

    Shu-Yi Liao, Angela L. Linderholm, Ken Y. Yoneda, Nicholas J. Kenyon, Richart W. Harper

    ERJ Open Res 5: 00123-2018; DOI: 10.1183/23120541.00123-2018 Published 18 February 2019
  • Open Access

    Interdevice agreement in respiratory resistance values by oscillometry in asthmatic children

    Francine M. Ducharme, Imane Jroundi, Guillaume Jean, Guillaume Lavoie Boutin, Christiane Lawson, Benjamin Vinet

    ERJ Open Res 5: 00138-2018; DOI: 10.1183/23120541.00138-2018 Published 18 March 2019

• Respiratory infections

  • Open Access

    Indoor air pollution and tobacco smoke exposure: impact on nasopharyngeal bacterial carriage in mothers and infants in an African birth cohort study

    Aneesa Vanker, Polite M. Nduru, Whitney Barnett, Felix S. Dube, Peter D. Sly, Robert P. Gie, Mark P. Nicol, Heather J. Zar

    ERJ Open Res 5: 00052-2018; DOI: 10.1183/23120541.00052-2018 Published 4 February 2019
  • Open Access

    Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: results of a 5-year follow-up cohort study

    William W. Siljan, Jan C. Holter, Annika E. Michelsen, Ståle H. Nymo, Trine Lauritzen, Kjersti Oppen, Einar Husebye, Thor Ueland, Tom E. Mollnes, Pål Aukrust, Lars Heggelund

    ERJ Open Res 5: 00014-2019; DOI: 10.1183/23120541.00014-2019 Published 10 March 2019
  • Open Access

    Soluble urokinase plasminogen activator receptor for the prediction of ventilator-associated pneumonia

    Pouline M. van Oort, Lieuwe D. Bos, Pedro Póvoa, Paula Ramirez, Antoni Torres, Antonio Artigas, Marcus J. Schultz, Ignacio Martin-Loeches

    ERJ Open Res 5: 00212-2018; DOI: 10.1183/23120541.00212-2018 Published 25 March 2019

• Lung cancer

  • Open Access

    Cancer gene mutations in congenital pulmonary airway malformation patients

    Jacob Shujui Hsu, Ruizhong Zhang, Fanny Yeung, Clara S.M. Tang, John K.L. Wong, Man-Ting So, Huimin Xia, Pak Sham, Paul K. Tam, Miaoxin Li, Kenneth K.Y. Wong, Maria-Mercè Garcia-Barcelo

    ERJ Open Res 5: 00196-2018; DOI: 10.1183/23120541.00196-2018 Published 4 February 2019
  • Open Access

    Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions

    Karlijn Hummelink, Mirte Muller, Theodora C. Linders, Vincent van der Noort, Petra M. Nederlof, Paul Baas, Sjaak Burgers, Egbert F. Smit, Gerrit A. Meijer, Michel M. van den Heuvel, Daan van den Broek, Kim Monkhorst

    ERJ Open Res 5: 00016-2019; DOI: 10.1183/23120541.00016-2019 Published 25 March 2019

• Paediatric pulmonology

  • Open Access

    Valved holding chamber drug delivery is dependent on breathing pattern and device design

    Péter Csonka, Lauri Lehtimäki

    ERJ Open Res 5: 00158-2018; DOI: 10.1183/23120541.00158-2018 Published 4 February 2019
  • Open Access

    Impact of a protocol-driven unified service for neonates with bronchopulmonary dysplasia

    Natalie Batey, Dushyant Batra, Jon Dorling, Jayesh Mahendra Bhatt

    ERJ Open Res 5: 00183-2018; DOI: 10.1183/23120541.00183-2018 Published 25 March 2019

• COPD

  • Open Access

    Patients' perspectives on COPD: findings from a social media listening study

    Nigel S. Cook, Konstantinos Kostikas, Jean-Bernard Gruenberger, Bhavik Shah, Purnima Pathak, Vinay Preet Kaur, Alaknanda Mudumby, Rajat Sharma, Florian S. Gutzwiller

    ERJ Open Res 5: 00128-2018; DOI: 10.1183/23120541.00128-2018 Published 10 February 2019
  • Open Access

    Tiotropium discontinuation in patients with early-stage COPD: a prospective observational cohort study

    Chenglong Li, Yumin Zhou, Sha Liu, Mengning Zheng, Jinzhen Zheng, Huanhuan Peng, Zhishan Deng, Nanshan Zhong, Pixin Ran

    ERJ Open Res 5: 00175-2018; DOI: 10.1183/23120541.00175-2018 Published 18 February 2019
  • Open Access

    Impact of pre-enrolment medication use on clinical outcomes in SUMMIT

    Jørgen Vestbo, Mark Dransfield, Julie A. Anderson, Robert D. Brook, Peter M.A. Calverley, Bartolome R. Celli, Nicholas J. Cowans, Courtney Crim, Fernando Martinez, David E. Newby, Julie Yates, Peter Lange

    ERJ Open Res 5: 00203-2018; DOI: 10.1183/23120541.00203-2018 Published 25 February 2019
  • Open Access

    Drivers of year-to-year variation in exacerbation frequency of COPD: analysis of the AERIS cohort

    Tom M.A. Wilkinson, Emmanuel Aris, Simon C. Bourne, Stuart C. Clarke, Mathieu Peeters, Thierry G. Pascal, Laura Taddei, Andrew C. Tuck, Viktoriya L. Kim, Kristoffer K. Ostridge, Karl J. Staples, Nicholas P. Williams, Anthony P. Williams, Stephen A. Wootton, Jeanne-Marie Devaster

    ERJ Open Res 5: 00248-2018; DOI: 10.1183/23120541.00248-2018 Published 25 February 2019
  • Open Access

    Treatment response in COPD: does FEV₁ say it all? A post hoc analysis of the CRYSTAL study

    Konstantinos Kostikas, Timm Greulich, Alexander J. Mackay, Nadine S. Lossi, Maryam Aalamian-Mattheis, Xavier Nunez, Veronica A. Pagano, Francesco Patalano, Andreas Clemens, Claus F. Vogelmeier

    ERJ Open Res 5: 00243-2018; DOI: 10.1183/23120541.00243-2018 Published 25 February 2019
  • Open Access

    Diagnosis and management of α₁-antitrypsin deficiency in Europe: an expert survey

    Ildikó Horváth, Maria Canotilho, Jan Chlumský, Joanna Chorostowska-Wynimko, Luciano Corda, Eric Derom, Joachim H. Ficker, Meinhard Kneussl, Marc Miravitlles, Maria Sucena, Gabriel Thabut, Alice M. Turner, Emily van ’t Wout, N. Gerard McElvaney

    ERJ Open Res 5: 00171-2018; DOI: 10.1183/23120541.00171-2018 Published 10 March 2019

• Pulmonary vascular diseases

  • Open Access

    Everyday life experiences of spouses of patients who suffer from pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension

    Bodil Ivarsson, Trygve Sjöberg, Roger Hesselstrand, Göran Rådegran, Barbro Kjellström

    ERJ Open Res 5: 00218-2018; DOI: 10.1183/23120541.00218-2018 Published 25 February 2019

• Surgery

  • Open Access

    Dysregulated alveolar function and complications in smokers following oesophagectomy

    Sebastian T. Lugg, Kerrie A. Alridge, Phillip A. Howells, Dhruv Parekh, Aaron Scott, Rahul Y. Mahida, Daniel Park, Olga Tucker, Fang Gao, Gavin D. Perkins, David R. Thickett, Rachel C.A. Dancer

    ERJ Open Res 5: 00089-2018; DOI: 10.1183/23120541.00089-2018 Published 3 March 2019

• Interstitial lung diseases

  • Open Access

    Combined pulmonary fibrosis and emphysema characteristics in a Greek cohort

    Foteini Malli, Despoina Papakosta, Katerina Antoniou, Maria Dimadi, Vlassis Polychronopoulos, Katerina Malagari, Anastasia Oikonomou, Demosthenes E. Bouros, Zoe Daniil

    ERJ Open Res 5: 00014-2018; DOI: 10.1183/23120541.00014-2018 Published 18 March 2019
  • Open Access

    Incidence of autoimmune pulmonary alveolar proteinosis estimated using Poisson distribution

    Nobutaka Kitamura, Shinya Ohkouchi, Ryushi Tazawa, Haruyuki Ishii, Toshinori Takada, Takuro Sakagami, Takahiro Tanaka, Koh Nakata

    ERJ Open Res 5: 00190-2018; DOI: 10.1183/23120541.00190-2018 Published 18 March 2019

• Bronchiectasis

  • Open Access

    Personalised anti-inflammatory therapy for bronchiectasis and cystic fibrosis: selecting patients for controlled trials of neutrophil elastase inhibition

    Holly R. Keir, Christopher J. Fong, Megan L. Crichton, Philip Barth, Eric Chevalier, Gill Brady, Gwen Kennedy, Johann Zimmermann, Piet L.B. Bruijnzeel, Alison J. Dicker, James D. Chalmers

    ERJ Open Res 5: 00252-2018; DOI: 10.1183/23120541.00252-2018 Published 25 March 2019