Extract
Chronic obstructive pulmonary disease (COPD) is characterised by chronic airflow limitation and inflammation of the airways and lung parenchyma. COPD is associated with many comorbidities, especially cardiovascular disease (CVD), which share similar risk factors with COPD [1].
Abstract
Circulating MFAP4 is a relevant biomarker to identify COPD patients at risk of death and cardiovascular comorbidity after smoking cessation http://ow.ly/6vnL30o8t1g
Footnotes
Conflict of interest: S.L. Johansson has nothing to disclose.
Conflict of interest: H. Wulf-Johansson has nothing to disclose.
Conflict of interest: A. Schlosser is an inventor of US Patent No. 9,988,442 and EP17199552.5 owned by University of Southern Denmark.
Conflict of interest: I.L. Titlestad has nothing to disclose.
Conflict of interest: B. Miller is an employee and shareholder of GSK.
Conflict of interest: R. Tal-Singer is an employee and shareholder of GSK.
Conflict of interest: U. Holmskov is an inventor of US Patent No. 9,988,442 and EP17199552.5 owned by University of Southern Denmark.
Conflict of interest: J. Vestbo reports consultancy fees for COPD Phase 2 and 3 programmes and payment for lectures including service in speaker bureaus from GlaxoSmithKline, Chiesi Pharmaceuticals, Boehringer-Ingelheim, Novartis and AstraZeneca, and an unconditional grant for biomarker research at Manchester University Hospital NHS Foundation Trust from Boehringer Ingelheim, outside the submitted work.
Conflict of interest: G.L. Sørensen is an inventor of US Patent No. 9,988,442 and EP17199552.5 owned by University of Southern Denmark.
Support statement: The study was sponsored by the Danish Strategic Research Council. J. Vestbo is supported by the NIHR Manchester Biomedical Research Centre. The ECLIPSE study (SCO104960, NCT00292552) was funded by GSK. Funding information for this article has been deposited with the Crossref Funder Registry.
- Received January 21, 2019.
- Accepted February 24, 2019.
- Copyright ©ERS 2019
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