Novel mouse model of indwelling pleural catheter in mice with malignant pleural effusion

a) The mouse indwelling pleural catheter. The catheter is composed of polyurethane tubing and a syringe accessible port, with syringe adapter. b) Mouse with the intrapleural catheter tunnelled through subcutaneous tissue, with a 22G syringe-accessible port on the distal end of the catheter. The port is sutured to skin. c) Pleural fluid drained from mice. The scatterplot shows the mean (and standard error of mean) volume of pleural fluid drained from 11 mice. Eight mice were excluded from the analysis because of technical issues.