Respiratory follow-up pre- and post-engineering controls or cessation of added diacetyl at four microwave popcorn facilities

James E. Lockey; Timothy J. Hilbert; Grace LeMasters; Kari K. Dunning; Roy T. McKay; Linda S. Levin; Carol H. Rice

doi:10.1183/23120541.00042-2019

Tables

TABLE 1

Relationship between job category and lung function for those beginning their employment pre-2003 (cohort 1) by sex and racial group

Variable	Non-Asian males (n=302)		Asian males (n=47)		Non-Asian females (n=181)
Variable	Estimated change in % predicted FEV₁ (p-value)	Estimated change in % predicted FVC (p-value)	Estimated change in % predicted FEV₁ (p-value)	Estimated change in % predicted FVC (p-value)	Estimated change in % predicted FEV₁ (p-value)	Estimated change in % predicted FVC (p-value)
Pack-years of smoking	−0.30 (<0.01)	−0.13 (<0.01)	−0.13 (0.27)	−0.03 (0.76)	−0.31 (<0.01)	−0.16 (0.05)
Current smoker^#	−0.37 (0.56)	−0.08 (0.88)	−0.91 (0.70)	2.9 (0.21)	−0.90 (0.32)	0.15 (0.86)
BMI at first PFT	−0.38 (<0.01)	−0.62 (<0.01)	−0.66 (0.12)	−1.13 (<0.01)	−0.14 (0.35)	−0.38 (<0.01)
BMI change since first PFT	−0.45 (<0.01)	−0.43 (<0.01)	−0.39 (0.36)	−0.38 (0.35)	−0.2 (0.01)	−0.27 (<0.01)
Time since first PFT	−0.57 (<0.01)	−0.55 (<0.01)	−0.39 (0.51)	0.75 (0.19)	−0.30 (0.02)	−0.23 (0.04)
Mixer	−7.92 (<0.01)	−1.78 (0.46)	−13.7 (<0.01)	−9.94 (0.02)	4.13 (0.44)	−0.70 (0.89)
Intermittent mixer	2.74 (0.10)	2.63 (0.07)	6.19 (0.15)	6.70 (0.12)	2.47 (0.65)	2.03 (0.69)
QA	2.05 (0.79)	4.06 (0.55)	NA	NA	−1.38 (0.70)	−2.12 (0.52)
Interaction mixer×time since first PFT^¶	0.02 (0.96)	−0.16 (0.64)	0.68 (0.62)	0.72 (0.59)	0.00 (0.99)	0.40 (0.43)
Interaction intermittent mixer×time since first PFT^¶	0.41 (0.06)	0.27 (0.17)	0.88 (0.34)	−0.12 (0.90)	−0.77 (0.12)	−0.61 (0.18)
Interaction QA×time since first PFT^¶	1.3 (0.29)	1.3 (0.26)	NA	NA	−0.71 (0.06)	−0.75 (0.04)

Non-Asian males: mixers (n=27), intermittent mixers (n=111), quality assurance operators (QA) (n=3), other (n=161); Asian males: mixers (n=7), intermittent mixers (n=6), QA (n=0), other (n=34); non-Asian females: mixers (n=8), intermittent mixers (n=8), QA (n=20), other (n=145). FEV₁: forced expiratory volume in 1 s; FVC: forced vital capacity; BMI: body mass index; PFT: pulmonary function test; NA: not applicable.^#: compared with never- and ex-smokers. ^¶: compared to “others” defined as employees without employment as pre-2003 mixer, pre-2003 intermittent mixer (maintenance and supervisors) or pre-2003 QA operator.