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Respiratory follow-up pre- and post-engineering controls or cessation of added diacetyl at four microwave popcorn facilities

James E. Lockey, Timothy J. Hilbert, Grace LeMasters, Kari K. Dunning, Roy T. McKay, Linda S. Levin, Carol H. Rice
ERJ Open Research 2019 5: 00042-2019; DOI: 10.1183/23120541.00042-2019
James E. Lockey
1University of Cincinnati College of Medicine, Depts of Environmental Health and Internal Medicine (Pulmonary Division), Cincinnati, OH, USA
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  • For correspondence: james.lockey@uc.edu
Timothy J. Hilbert
2University of Cincinnati College of Medicine, Dept of Environmental Health, Cincinnati, OH, USA
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Grace LeMasters
2University of Cincinnati College of Medicine, Dept of Environmental Health, Cincinnati, OH, USA
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Kari K. Dunning
2University of Cincinnati College of Medicine, Dept of Environmental Health, Cincinnati, OH, USA
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Roy T. McKay
2University of Cincinnati College of Medicine, Dept of Environmental Health, Cincinnati, OH, USA
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Linda S. Levin
2University of Cincinnati College of Medicine, Dept of Environmental Health, Cincinnati, OH, USA
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Carol H. Rice
2University of Cincinnati College of Medicine, Dept of Environmental Health, Cincinnati, OH, USA
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Tables

  • TABLE 1

    Relationship between job category and lung function for those beginning their employment pre-2003 (cohort 1) by sex and racial group

    VariableNon-Asian males (n=302)Asian males (n=47)Non-Asian females (n=181)
    Estimated change in % predicted FEV1 (p-value)Estimated change in % predicted FVC (p-value)Estimated change in % predicted FEV1 (p-value)Estimated change in % predicted FVC (p-value)Estimated change in % predicted FEV1 (p-value)Estimated change in % predicted FVC (p-value)
    Pack-years of smoking−0.30 (<0.01)−0.13 (<0.01)−0.13 (0.27)−0.03 (0.76)−0.31 (<0.01)−0.16 (0.05)
    Current smoker#−0.37 (0.56)−0.08 (0.88)−0.91 (0.70)2.9 (0.21)−0.90 (0.32)0.15 (0.86)
    BMI at first PFT−0.38 (<0.01)−0.62 (<0.01)−0.66 (0.12)−1.13 (<0.01)−0.14 (0.35)−0.38 (<0.01)
    BMI change since first PFT−0.45 (<0.01)−0.43 (<0.01)−0.39 (0.36)−0.38 (0.35)−0.2 (0.01)−0.27 (<0.01)
    Time since first PFT−0.57 (<0.01)−0.55 (<0.01)−0.39 (0.51)0.75 (0.19)−0.30 (0.02)−0.23 (0.04)
    Mixer−7.92 (<0.01)−1.78 (0.46)−13.7 (<0.01)−9.94 (0.02)4.13 (0.44)−0.70 (0.89)
    Intermittent mixer2.74 (0.10)2.63 (0.07)6.19 (0.15)6.70 (0.12)2.47 (0.65)2.03 (0.69)
    QA2.05 (0.79)4.06 (0.55)NANA−1.38 (0.70)−2.12 (0.52)
    Interaction mixer×time since first PFT¶0.02 (0.96)−0.16 (0.64)0.68 (0.62)0.72 (0.59)0.00 (0.99)0.40 (0.43)
    Interaction intermittent mixer×time since first PFT¶0.41 (0.06)0.27 (0.17)0.88 (0.34)−0.12 (0.90)−0.77 (0.12)−0.61 (0.18)
    Interaction QA×time since first PFT¶1.3 (0.29)1.3 (0.26)NANA−0.71 (0.06)−0.75 (0.04)

    Non-Asian males: mixers (n=27), intermittent mixers (n=111), quality assurance operators (QA) (n=3), other (n=161); Asian males: mixers (n=7), intermittent mixers (n=6), QA (n=0), other (n=34); non-Asian females: mixers (n=8), intermittent mixers (n=8), QA (n=20), other (n=145). FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; BMI: body mass index; PFT: pulmonary function test; NA: not applicable.#: compared with never- and ex-smokers. ¶: compared to “others” defined as employees without employment as pre-2003 mixer, pre-2003 intermittent mixer (maintenance and supervisors) or pre-2003 QA operator.

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    Respiratory follow-up pre- and post-engineering controls or cessation of added diacetyl at four microwave popcorn facilities
    James E. Lockey, Timothy J. Hilbert, Grace LeMasters, Kari K. Dunning, Roy T. McKay, Linda S. Levin, Carol H. Rice
    ERJ Open Research Jul 2019, 5 (3) 00042-2019; DOI: 10.1183/23120541.00042-2019

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    Respiratory follow-up pre- and post-engineering controls or cessation of added diacetyl at four microwave popcorn facilities
    James E. Lockey, Timothy J. Hilbert, Grace LeMasters, Kari K. Dunning, Roy T. McKay, Linda S. Levin, Carol H. Rice
    ERJ Open Research Jul 2019, 5 (3) 00042-2019; DOI: 10.1183/23120541.00042-2019
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