ERJ Open Research: 5 (4)

01 October 2019; volume 5, issue 4

Study protocols

Open Access
A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol
Caroline Wright, Simon P. Hart, Victoria Allgar, Anne English, Flavia Swan, Judith Dyson, Gerry Richardson, Maureen Twiddy, Judith Cohen, Jamilla Hussain, Miriam Johnson, Ian Hargreaves, Michael G. Crooks

ERJ Open Res 5: 00186-2019; DOI: 10.1183/23120541.00186-2019 Published 21 October 2019
Open Access
Clinical effectiveness of once-daily fluticasone furoate/umeclidinium/vilanterol in usual practice: the COPD INTREPID study design
Sally Worsley, Neil Snowise, David M.G. Halpin, Dawn Midwinter, Afisi S. Ismaila, Elaine Irving, Leah Sansbury, Maggie Tabberer, David Leather, Chris Compton

ERJ Open Res 5: 00061-2019; DOI: 10.1183/23120541.00061-2019 Published 4 November 2019

Original articles

Tuberculosis
- Open Access
  Comparison of the QuantiFERON-TB and tuberculin skin test for detection of latent tuberculosis infection in cancer patients in a developing country
  Javier Leonardo Galindo, Adriana Catalina Galeano, David Alfonso Suarez-Zamora, Ana Milena Callejas, Mónica Patricia Caicedo-Verástegui, Darío Londoño, Luis Gerardo García-Herreros, Aylen Vanessa Ospina-Serrano, Alfredo Saavedra, Plutarco Garcíaherreros, Diana María Palacios, Margarita Baldión
  
  ERJ Open Res 5: 00258-2018; DOI: 10.1183/23120541.00258-2018 Published 15 October 2019
- Open Access
  Time to diagnosis of tuberculosis is greater in older patients: a retrospective cohort review
  Aula Abbara, Simon M. Collin, Onn M. Kon, Kevin Buell, Adam Sullivan, Jessica Barrett, Tumena Corrah, Alastair McGregor, Trevor Hansel, Laurence John, Robert N. Davidson
  
  ERJ Open Res 5: 00228-2018; DOI: 10.1183/23120541.00228-2018 Published 4 November 2019
- Open Access
  EBUS-TBNA in the rapid microbiological diagnosis of drug-resistant mediastinal tuberculous lymphadenopathy
  Prashant N. Chhajed, Preyas J. Vaidya, Neha P. Mandovra, Vinod B. Chavhan, Tejashree T. Lele, Rekha Nair, Jörg D. Leuppi, Avinandan Saha
  
  ERJ Open Res 5: 00008-2019; DOI: 10.1183/23120541.00008-2019 Published 15 November 2019
- Open Access
  Trends and risk factors for death and excess all-cause mortality among notified tuberculosis patients in the UK: an analysis of surveillance data
  Debora Pedrazzoli, Katharina Kranzer, H. Lucy Thomas, Maeve K. Lalor
  
  ERJ Open Res 5: 00125-2019; DOI: 10.1183/23120541.00125-2019 Published 16 December 2019
Methamphetamines and pulmonary disease
- Open Access
  Methamphetamine use association with pulmonary diseases: a retrospective investigation of hospital discharges in California from 2005 to 2011
  Halley Tsai, Justin Lee, Haley Hedlin, Roham T. Zamanian, Vinicio A. de Jesus Perez
  
  ERJ Open Res 5: 00017-2019; DOI: 10.1183/23120541.00017-2019 Published 15 October 2019
Bronchiolitis obliterans syndrome
- Open Access
  Lung clearance index in detection of post-transplant bronchiolitis obliterans syndrome
  Madeleine Driskel, Alex Horsley, Laurice Fretwell, Nigel Clayton, Mohamed Al-Aloul
  
  ERJ Open Res 5: 00164-2019; DOI: 10.1183/23120541.00164-2019 Published 15 October 2019
- Open Access
  A randomised single-centre trial of inhaled liposomal cyclosporine for bronchiolitis obliterans syndrome post-lung transplantation
  Aldo Iacono, Marniker Wijesinha, Keshava Rajagopal, Natalia Murdock, Irina Timofte, Bartley Griffith, Michael Terrin
  
  ERJ Open Res 5: 00167-2019; DOI: 10.1183/23120541.00167-2019 Published 30 October 2019
Lung imaging
- Open Access
  Performance of transbronchial cryobiopsy in eccentrically and adjacently orientated radial endobronchial ultrasound lesions
  Sze Shyang Kho, Swee Kim Chan, Mei Ching Yong, Siew Teck Tie
  
  ERJ Open Res 5: 00135-2019; DOI: 10.1183/23120541.00135-2019 Published 21 October 2019
Interstitial lung disease
- Open Access
  Diagnostic yield and safety of transbronchial cryobiopsy in sarcoidosis
  Maria Jacob, Hélder Novais Bastos, Patrícia Caetano Mota, Natália Melo, Rui Cunha, José Miguel Pereira, Susana Guimarães, Conceição Souto Moura, António Morais
  
  ERJ Open Res 5: 00203-2019; DOI: 10.1183/23120541.00203-2019 Published 21 October 2019
- Open Access
  Incidence, comorbidity and survival rate of hypersensitivity pneumonitis: a national population-based study
  Anne Hald Rittig, Ole Hilberg, Rikke Ibsen, Anders Løkke
  
  ERJ Open Res 5: 00259-2018; DOI: 10.1183/23120541.00259-2018 Published 21 October 2019
- Open Access
  Gaps in care of patients living with pulmonary fibrosis: a joint patient and expert statement on the results of a Europe-wide survey
  Catharina C. Moor, Marlies S. Wijsenbeek, Elisabetta Balestro, Davide Biondini, Benjamin Bondue, Vincent Cottin, Ron Flewett, Liam Galvin, Steve Jones, Maria Molina-Molina, Lurdes Planas-Cerezales, Antje Prasse, Helmut Prosch, Anne-Marie Russell, Michel Viegas, Guenther Wanke, Wim Wuyts, Michael Kreuter, Francesco Bonella
  
  ERJ Open Res 5: 00124-2019; DOI: 10.1183/23120541.00124-2019 Published 21 October 2019
- Open Access
  Results of the standard set for pulmonary sarcoidosis: feasibility and multicentre outcomes
  Nynke A. Kampstra, Paul B. van der Nat, Lea M. Dijksman, Frouke T. van Beek, Daniel A. Culver, Robert P. Baughman, Elisabetta A. Renzoni, Wim Wuyts, Vasilis Kouranos, Pieter Zanen, Marlies S. Wijsenbeek, Marinus J.C. Eijkemans, Douwe H. Biesma, Philip J. van der Wees, Jan C. Grutters
  
  ERJ Open Res 5: 00094-2019; DOI: 10.1183/23120541.00094-2019 Published 30 October 2019
- Open Access
  miR-200 family members reduce senescence and restore idiopathic pulmonary fibrosis type II alveolar epithelial cell transdifferentiation
  Silvia Moimas, Francesco Salton, Beata Kosmider, Nadja Ring, Maria C. Volpe, Karim Bahmed, Luca Braga, Michael Rehman, Simone Vodret, Maria Laura Graziani, Marla R. Wolfson, Nathaniel Marchetti, Thomas J. Rogers, Mauro Giacca, Gerard J. Criner, Serena Zacchigna, Marco Confalonieri
  
  ERJ Open Res 5: 00138-2019; DOI: 10.1183/23120541.00138-2019 Published 16 December 2019
Cystic fibrosis
- Open Access
  Variable agreement between wearable heart rate monitors during exercise in cystic fibrosis
  Madeline Gaynor, Abbey Sawyer, Sue Jenkins, Jamie Wood
  
  ERJ Open Res 5: 00006-2019; DOI: 10.1183/23120541.00006-2019 Published 30 October 2019
- Open Access
  Simultaneous sulfur hexafluoride and nitrogen multiple-breath washout (MBW) to examine inherent differences in MBW outcomes
  Katie J. Bayfield, Alex Horsley, Eric Alton, Samantha Irving, Andrew Bush, Jane C. Davies
  
  ERJ Open Res 5: 00234-2018; DOI: 10.1183/23120541.00234-2018 Published 4 November 2019
- Open Access
  Impact of Achromobacter xylosoxidans isolation on the respiratory function of adult patients with cystic fibrosis
  Macha Tetart, Frederic Wallet, Maeva Kyheng, Sylvie Leroy, Thierry Perez, Olivier Le Rouzic, Benoit Wallaert, Anne Prevotat
  
  ERJ Open Res 5: 00051-2019; DOI: 10.1183/23120541.00051-2019 Published 8 December 2019
Asthma
- Open Access
  Prevalence of oral corticosteroid use in the German severe asthma population
  Christian Taube, Peter Bramlage, Annette Hofer, Dörte Anderson
  
  ERJ Open Res 5: 00092-2019; DOI: 10.1183/23120541.00092-2019 Published 30 October 2019
- Open Access
  FASE-CPHG study: a panoramic snapshot of difficult-to-treat, severe asthma in French nonacademic hospitals
  Laurent Portel, Eric Parrat, Cécilia Nocent-Ejnaini, Gilles Mangiapan, Anne Prud'homme, Jean-Philippe Oster, Corinne Aperre de Vecchi, Cyril Maurer, Chantal Raherison, Didier Debieuvre
  
  ERJ Open Res 5: 00069-2019; DOI: 10.1183/23120541.00069-2019 Published 30 October 2019
- Open Access
  Real-life effectiveness of omalizumab in difficult-to-treat versus severe asthma: a national cohort study in Belgium
  Katia M.C. Verhamme, Catherine Lucet, Alain Van Meerhaeghe, Guy G.O. Brusselle, Marie-Laurence Lambert
  
  ERJ Open Res 5: 00253-2018; DOI: 10.1183/23120541.00253-2018 Published 25 November 2019
- Open Access
  Sex differences in health services and medication use among older adults with asthma
  Teresa To, Natasha Gray, Kandace Ryckman, Jingqin Zhu, Ivy Fong, Andrea Gershon
  
  ERJ Open Res 5: 00242-2019; DOI: 10.1183/23120541.00242-2019 Published 2 December 2019
- Open Access
  Efficacy of azithromycin in severe asthma from the AMAZES randomised trial
  Peter G. Gibson, Ian A. Yang, John W. Upham, Paul N. Reynolds, Sandra Hodge, Alan L. James, Christine Jenkins, Matthew J. Peters, Guy B. Marks, Melissa Baraket, Heather Powell, Jodie L. Simpson
  
  ERJ Open Res 5: 00056-2019; DOI: 10.1183/23120541.00056-2019 Published 23 December 2019
Bronchiectasis
- Open Access
  Recommendations for travelling with bronchiectasis: a joint ELF/EMBARC/ERN-Lung collaboration
  Michal Shteinberg, Barbara Crossley, Tal Lavie, Sima Nadler, Jeanette Boyd, Felix C. Ringshausen, Tim Aksamit, James D. Chalmers, Pieter Goeminne
  
  ERJ Open Res 5: 00113-2019; DOI: 10.1183/23120541.00113-2019 Published 30 October 2019
- Open Access
  Predictors of non-cystic fibrosis bronchiectasis in Indigenous adult residents of central Australia: results of a case–control study
  Lloyd Einsiedel, Hai Pham, Virginia Au, Saba Hatami, Kim Wilson, Tim Spelman, Hubertus Jersmann
  
  ERJ Open Res 5: 00001-2019; DOI: 10.1183/23120541.00001-2019 Published 2 December 2019
Lung transplantation
- Open Access
  Pregnancy after lung and heart–lung transplantation: a French multicentre retrospective study of 39 pregnancies
  Charlotte Bry, Dominique Hubert, Martine Reynaud-Gaubert, Claire Dromer, Hervé Mal, Antoine Roux, Véronique Boussaud, Johanna Claustre, Jérôme Le Pavec, Muriel Murris-Espin, Isabelle Danner-Boucher
  
  ERJ Open Res 5: 00254-2018; DOI: 10.1183/23120541.00254-2018 Published 30 October 2019
COPD
- Open Access
  Behavioural interventions targeting physical activity improve psychocognitive outcomes in COPD
  Kim L. Lavoie, Maria Sedeno, Alan Hamilton, Pei-Zhi Li, Dorothy De Sousa, Thierry Troosters, François Maltais, Jean Bourbeau
  
  ERJ Open Res 5: 00013-2019; DOI: 10.1183/23120541.00013-2019 Published 4 November 2019
- Open Access
  Isolating peripheral effects of endogenous opioids in modulating exertional breathlessness in people with moderate or severe COPD: a randomised controlled trial
  David C. Currow, Toby Hunt, Sandra Louw, Danny Eckert, Peter Allcroft, Tim H.M. To, Aine Greene, Malgorzata Krajnik, Don Mahler, Magnus Ekström
  
  ERJ Open Res 5: 00153-2019; DOI: 10.1183/23120541.00153-2019 Published 23 December 2019
Respiratory infections
- Open Access
  Changing epidemiology of nontuberculous mycobacterial lung disease over the last two decades in a region of the Basque country
  Sandra Pedrero, Eva Tabernero, Eunate Arana-Arri, Elena Urra, Maialen Larrea, Rafael Zalacain
  
  ERJ Open Res 5: 00110-2018; DOI: 10.1183/23120541.00110-2018 Published 4 November 2019
- Open Access
  Association of atypical antipsychotics and mortality for patients hospitalised with pneumonia
  Zachary Boivin, Mario F. Perez, Nkiruka C. Atuegwu, Mark Metersky, Carlos A. Alvarez, Antonio Anzueto, Eric M. Mortensen
  
  ERJ Open Res 5: 00223-2018; DOI: 10.1183/23120541.00223-2018 Published 4 November 2019
Pulmonary vascular disease
- Open Access
  Plasma receptor tyrosine kinase RET in pulmonary arterial hypertension diagnosis and differentiation
  Joanna Säleby, Habib Bouzina, Salaheldin Ahmed, Jakob Lundgren, Göran Rådegran
  
  ERJ Open Res 5: 00037-2019; DOI: 10.1183/23120541.00037-2019 Published 15 November 2019
Lung function
- Open Access
  Prognostic significance of pulmonary function tests in dyskeratosis congenita, a telomere biology disorder
  Neelam Giri, Sandhiya Ravichandran, Youjin Wang, Shahinaz M. Gadalla, Blanche P. Alter, Joseph Fontana, Sharon A. Savage
  
  ERJ Open Res 5: 00209-2019; DOI: 10.1183/23120541.00209-2019 Published 15 November 2019
- Open Access
  Comparison of oscillometry devices using active mechanical test loads
  Ronald J. Dandurand, Jean-Pierre Lavoie, Larry C. Lands, Zoltán Hantos, the Oscillometry Harmonisation Study Group
  
  ERJ Open Res 5: 00160-2019; DOI: 10.1183/23120541.00160-2019 Published 23 December 2019
Snus and infant birth size
- Open Access
  Snus in pregnancy and infant birth size: a mother–child birth cohort study
  Ina Kreyberg, Katarina Hilde, Karen Eline S. Bains, Kai-Håkon Carlsen, Berit Granum, Guttorm Haugen, Gunilla Hedlin, Christine M. Jonassen, Live S. Nordhagen, Björn Nordlund, Corina S. Rueegg, Katrine D. Sjøborg, Håvard O. Skjerven, Anne C. Staff, Riyas Vettukattil, Karin C. Lødrup Carlsen, the PreventADALL Study Group
  
  ERJ Open Res 5: 00255-2019; DOI: 10.1183/23120541.00255-2019 Published 2 December 2019
Cough
- Open Access
  Efficacy of two dosing schemes of a liquid containing ivy leaves dry extract EA 575 versus placebo in the treatment of acute bronchitis in adults
  Axel Schaefer, Fanny Ludwig, Bruno M. Giannetti, Michael Bulitta, Anja Wacker
  
  ERJ Open Res 5: 00019-2019; DOI: 10.1183/23120541.00019-2019 Published 8 December 2019
- Open Access
  Prevalence of chronic wet cough and protracted bacterial bronchitis in Aboriginal children
  Pamela Laird, James Totterdell, Roz Walker, Anne B. Chang, André Schultz
  
  ERJ Open Res 5: 00248-2019; DOI: 10.1183/23120541.00248-2019 Published 8 December 2019
Pulmonary rehabilitation
- Open Access
  Prevalence of comorbidities and impact on pulmonary rehabilitation outcomes
  Stacey J. Butler, Lok Sze Katrina Li, Lauren Ellerton, Andrea S. Gershon, Roger S. Goldstein, Dina Brooks
  
  ERJ Open Res 5: 00264-2019; DOI: 10.1183/23120541.00264-2019 Published 8 December 2019
Lung cancer
- Open Access
  Tumour growth rate as a tool for response evaluation during PD-1 treatment for non-small cell lung cancer: a retrospective analysis
  Deirdre M.H.J. ten Berge, Daniel P. Hurkmans, Ilse den Besten, Jeroen S. Kloover, Ron H.J. Mathijssen, Reno Debets, Egbert F. Smit, Joachim G.J.V. Aerts
  
  ERJ Open Res 5: 00179-2019; DOI: 10.1183/23120541.00179-2019 Published 16 December 2019
E-cigarettes
- Open Access
  Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries
  Kameshwar P. Singh, Gina Lawyer, Thivanka Muthumalage, Krishna P. Maremanda, Naushad Ahmad Khan, Samantha R. McDonough, Dongxia Ye, Scott McIntosh, Irfan Rahman
  
  ERJ Open Res 5: 00182-2019; DOI: 10.1183/23120541.00182-2019 Published 23 December 2019

Original research letters

Open Access
Occult malignancy underlying a case of “hyperacute” onset of severe pulmonary hypertension
Maria Rosaria Gioia, Uberto Maccari, Luca Marchetti, Enivarco Maglioni, Giuseppina Ciarleglio, Valentina Granese, Laura Salerno, Luigi Spagnoli, Ilenia Zanellato, Maria Raffaella Ambrosio, Andrea Bianco, Raffaele Scala

ERJ Open Res 5: 00157-2019; DOI: 10.1183/23120541.00157-2019 Published 15 October 2019
Open Access
Effect of facial skin cooling induced by a handheld fan on the cough reflex threshold and urge to cough induced by citric acid
Masashi Kanezaki, Satoru Ebihara

ERJ Open Res 5: 00089-2019; DOI: 10.1183/23120541.00089-2019 Published 15 October 2019
Open Access
Assessing small airways dysfunction in asthma, asthma remission and healthy controls using particles in exhaled air
Orestes A. Carpaij, Susan Muiser, Alex J. Bell, Huib A.M. Kerstjens, Craig J. Galban, Aleksa B. Fortuna, Salman Siddiqui, Anna-Carin Olin, Martijn C. Nawijn, Maarten van den Berge

ERJ Open Res 5: 00202-2019; DOI: 10.1183/23120541.00202-2019 Published 21 October 2019
Open Access
Occupational exposures and asthma–COPD overlap in a clinical cohort of adult-onset asthma
Minna Tommola, Pinja Ilmarinen, Leena E. Tuomisto, Lauri Lehtimäki, Hannu Kankaanranta

ERJ Open Res 5: 00191-2019; DOI: 10.1183/23120541.00191-2019 Published 21 October 2019
Open Access
De novo bronchiectasis in haematological malignancies: patient characteristics, risk factors and survival
Ricardo J. José, Jocelin Hall, Jeremy S. Brown

ERJ Open Res 5: 00166-2019; DOI: 10.1183/23120541.00166-2019 Published 4 November 2019
Open Access
Asthma and body mass definitions affect estimates of association: evidence from a community-based cross-sectional survey
Francisca de Castro Mendes, Inês Paciência, João Cavaleiro Rufo, Diana Silva, Pedro Cunha, Mariana Farraia, Luís Delgado, Pedro Moreira, André Moreira

ERJ Open Res 5: 00076-2019; DOI: 10.1183/23120541.00076-2019 Published 4 November 2019
Open Access
Cholinergic synapse pathway gene polymorphisms associated with allergen-induced late asthmatic responses
Ashwini Rajasekaran, Daniel He, Alice Yue, Amrit Singh, Casey P. Shannon, J. Mark FitzGerald, Louis-Philippe Boulet, Paul M. O'Byrne, Gail M. Gauvreau, Scott J. Tebbutt

ERJ Open Res 5: 00107-2019; DOI: 10.1183/23120541.00107-2019 Published 4 November 2019
Open Access
A systematic evaluation of the diagnostic criteria for COPD and exacerbations used in randomised controlled trials on the management of COPD exacerbations
Alexander G. Mathioudakis, Julie Janner, Mia Moberg, Pablo Alonso-Coello, Jørgen Vestbo

ERJ Open Res 5: 00136-2019; DOI: 10.1183/23120541.00136-2019 Published 15 November 2019
Open Access
The obesity paradox in pulmonary arterial hypertension: the Scottish perspective
Luke Lawson McLean, Katherine Pellino, Melanie Brewis, Andrew Peacock, Martin Johnson, Alistair Colin Church

ERJ Open Res 5: 00241-2019; DOI: 10.1183/23120541.00241-2019 Published 25 November 2019
Open Access
Rapid and sustained airway control in metastatic malignant melanoma: a case report
Sarah Cullivan, John Bruzzi, Teresa McHale, Ramadan Shatwan, Paul Donnellan, David P. Breen

ERJ Open Res 5: 00050-2019; DOI: 10.1183/23120541.00050-2019 Published 2 December 2019
Open Access
Suppression of F_ENO with observed inhaled corticosteroid therapy in severe asthma: is it a useful test in clinical practice?
Shoaib Faruqi, Sean Zhou, Joanne Thompson, Terry Robinson, Karen Watkins, Helena Cummings, Nicola Jackson, Anoop Prakash, Michael Crooks

ERJ Open Res 5: 00123-2019; DOI: 10.1183/23120541.00123-2019 Published 25 November 2019
Open Access
Serum levels of L1-ORF1p and airflow limitation
Stefano Guerra, Monica M. Vasquez, Pasano Bojang, Irma N. Ramos, Duane L. Sherrill, Fernando D. Martinez, Marilyn Halonen, Kenneth S. Ramos

ERJ Open Res 5: 00247-2018; DOI: 10.1183/23120541.00247-2018 Published 25 November 2019
Open Access
Factors predicting progression of exercise training loads in people with interstitial lung disease
Atsuhito Nakazawa, Leona M. Dowman, Narelle S. Cox, Christine F. McDonald, Catherine J. Hill, Annemarie L. Lee, Anne E. Holland

ERJ Open Res 5: 00245-2018; DOI: 10.1183/23120541.00245-2018 Published 8 December 2019
Open Access
Understanding the mechanism of bronchial thermoplasty using airway volume assessed by computed tomography
David Langton, Peter B. Noble, Frank Thien, Graham M. Donovan

ERJ Open Res 5: 00272-2019; DOI: 10.1183/23120541.00272-2019 Published 23 December 2019

Correspondence

Open Access
SAPS3-CNIV score to predict hospital mortality following noninvasive ventilation: methodology insights
Jun Duan, Bushra Mina, Antonio M. Esquinas

ERJ Open Res 5: 00143-2019; DOI: 10.1183/23120541.00143-2019 Published 23 December 2019

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Table of Contents

Study protocols

Original articles

Tuberculosis

Methamphetamines and pulmonary disease

Bronchiolitis obliterans syndrome

Lung imaging

Interstitial lung disease

Cystic fibrosis

Asthma

Bronchiectasis

Lung transplantation

COPD

Respiratory infections

Pulmonary vascular disease

Lung function

Snus and infant birth size

Cough

Pulmonary rehabilitation

Lung cancer

E-cigarettes

Original research letters

Correspondence

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