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Table of Contents

01 October 2019; volume 5, issue 4

Study protocols

  • Open Access
    A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol
    Caroline Wright, Simon P. Hart, Victoria Allgar, Anne English, Flavia Swan, Judith Dyson, Gerry Richardson, Maureen Twiddy, Judith Cohen, Jamilla Hussain, Miriam Johnson, Ian Hargreaves, Michael G. Crooks
    ERJ Open Res 5: 00186-2019; DOI: 10.1183/23120541.00186-2019 Published 21 October 2019
  • Open Access
    Clinical effectiveness of once-daily fluticasone furoate/umeclidinium/vilanterol in usual practice: the COPD INTREPID study design
    Sally Worsley, Neil Snowise, David M.G. Halpin, Dawn Midwinter, Afisi S. Ismaila, Elaine Irving, Leah Sansbury, Maggie Tabberer, David Leather, Chris Compton
    ERJ Open Res 5: 00061-2019; DOI: 10.1183/23120541.00061-2019 Published 4 November 2019

Original articles

  • Tuberculosis

    • Open Access
      Comparison of the QuantiFERON-TB and tuberculin skin test for detection of latent tuberculosis infection in cancer patients in a developing country
      Javier Leonardo Galindo, Adriana Catalina Galeano, David Alfonso Suarez-Zamora, Ana Milena Callejas, Mónica Patricia Caicedo-Verástegui, Darío Londoño, Luis Gerardo García-Herreros, Aylen Vanessa Ospina-Serrano, Alfredo Saavedra, Plutarco Garcíaherreros, Diana María Palacios, Margarita Baldión
      ERJ Open Res 5: 00258-2018; DOI: 10.1183/23120541.00258-2018 Published 15 October 2019
    • Open Access
      Time to diagnosis of tuberculosis is greater in older patients: a retrospective cohort review
      Aula Abbara, Simon M. Collin, Onn M. Kon, Kevin Buell, Adam Sullivan, Jessica Barrett, Tumena Corrah, Alastair McGregor, Trevor Hansel, Laurence John, Robert N. Davidson
      ERJ Open Res 5: 00228-2018; DOI: 10.1183/23120541.00228-2018 Published 4 November 2019
    • Open Access
      EBUS-TBNA in the rapid microbiological diagnosis of drug-resistant mediastinal tuberculous lymphadenopathy
      Prashant N. Chhajed, Preyas J. Vaidya, Neha P. Mandovra, Vinod B. Chavhan, Tejashree T. Lele, Rekha Nair, Jörg D. Leuppi, Avinandan Saha
      ERJ Open Res 5: 00008-2019; DOI: 10.1183/23120541.00008-2019 Published 15 November 2019
    • Open Access
      Trends and risk factors for death and excess all-cause mortality among notified tuberculosis patients in the UK: an analysis of surveillance data
      Debora Pedrazzoli, Katharina Kranzer, H. Lucy Thomas, Maeve K. Lalor
      ERJ Open Res 5: 00125-2019; DOI: 10.1183/23120541.00125-2019 Published 16 December 2019
  • Methamphetamines and pulmonary disease

    • Open Access
      Methamphetamine use association with pulmonary diseases: a retrospective investigation of hospital discharges in California from 2005 to 2011
      Halley Tsai, Justin Lee, Haley Hedlin, Roham T. Zamanian, Vinicio A. de Jesus Perez
      ERJ Open Res 5: 00017-2019; DOI: 10.1183/23120541.00017-2019 Published 15 October 2019
  • Bronchiolitis obliterans syndrome

    • Open Access
      Lung clearance index in detection of post-transplant bronchiolitis obliterans syndrome
      Madeleine Driskel, Alex Horsley, Laurice Fretwell, Nigel Clayton, Mohamed Al-Aloul
      ERJ Open Res 5: 00164-2019; DOI: 10.1183/23120541.00164-2019 Published 15 October 2019
    • Open Access
      A randomised single-centre trial of inhaled liposomal cyclosporine for bronchiolitis obliterans syndrome post-lung transplantation
      Aldo Iacono, Marniker Wijesinha, Keshava Rajagopal, Natalia Murdock, Irina Timofte, Bartley Griffith, Michael Terrin
      ERJ Open Res 5: 00167-2019; DOI: 10.1183/23120541.00167-2019 Published 30 October 2019
  • Lung imaging

    • Open Access
      Performance of transbronchial cryobiopsy in eccentrically and adjacently orientated radial endobronchial ultrasound lesions
      Sze Shyang Kho, Swee Kim Chan, Mei Ching Yong, Siew Teck Tie
      ERJ Open Res 5: 00135-2019; DOI: 10.1183/23120541.00135-2019 Published 21 October 2019
  • Interstitial lung disease

    • Open Access
      Diagnostic yield and safety of transbronchial cryobiopsy in sarcoidosis
      Maria Jacob, Hélder Novais Bastos, Patrícia Caetano Mota, Natália Melo, Rui Cunha, José Miguel Pereira, Susana Guimarães, Conceição Souto Moura, António Morais
      ERJ Open Res 5: 00203-2019; DOI: 10.1183/23120541.00203-2019 Published 21 October 2019
    • Open Access
      Incidence, comorbidity and survival rate of hypersensitivity pneumonitis: a national population-based study
      Anne Hald Rittig, Ole Hilberg, Rikke Ibsen, Anders Løkke
      ERJ Open Res 5: 00259-2018; DOI: 10.1183/23120541.00259-2018 Published 21 October 2019
    • Open Access
      Gaps in care of patients living with pulmonary fibrosis: a joint patient and expert statement on the results of a Europe-wide survey
      Catharina C. Moor, Marlies S. Wijsenbeek, Elisabetta Balestro, Davide Biondini, Benjamin Bondue, Vincent Cottin, Ron Flewett, Liam Galvin, Steve Jones, Maria Molina-Molina, Lurdes Planas-Cerezales, Antje Prasse, Helmut Prosch, Anne-Marie Russell, Michel Viegas, Guenther Wanke, Wim Wuyts, Michael Kreuter, Francesco Bonella
      ERJ Open Res 5: 00124-2019; DOI: 10.1183/23120541.00124-2019 Published 21 October 2019
    • Open Access
      Results of the standard set for pulmonary sarcoidosis: feasibility and multicentre outcomes
      Nynke A. Kampstra, Paul B. van der Nat, Lea M. Dijksman, Frouke T. van Beek, Daniel A. Culver, Robert P. Baughman, Elisabetta A. Renzoni, Wim Wuyts, Vasilis Kouranos, Pieter Zanen, Marlies S. Wijsenbeek, Marinus J.C. Eijkemans, Douwe H. Biesma, Philip J. van der Wees, Jan C. Grutters
      ERJ Open Res 5: 00094-2019; DOI: 10.1183/23120541.00094-2019 Published 30 October 2019
    • Open Access
      miR-200 family members reduce senescence and restore idiopathic pulmonary fibrosis type II alveolar epithelial cell transdifferentiation
      Silvia Moimas, Francesco Salton, Beata Kosmider, Nadja Ring, Maria C. Volpe, Karim Bahmed, Luca Braga, Michael Rehman, Simone Vodret, Maria Laura Graziani, Marla R. Wolfson, Nathaniel Marchetti, Thomas J. Rogers, Mauro Giacca, Gerard J. Criner, Serena Zacchigna, Marco Confalonieri
      ERJ Open Res 5: 00138-2019; DOI: 10.1183/23120541.00138-2019 Published 16 December 2019
  • Cystic fibrosis

    • Open Access
      Variable agreement between wearable heart rate monitors during exercise in cystic fibrosis
      Madeline Gaynor, Abbey Sawyer, Sue Jenkins, Jamie Wood
      ERJ Open Res 5: 00006-2019; DOI: 10.1183/23120541.00006-2019 Published 30 October 2019
    • Open Access
      Simultaneous sulfur hexafluoride and nitrogen multiple-breath washout (MBW) to examine inherent differences in MBW outcomes
      Katie J. Bayfield, Alex Horsley, Eric Alton, Samantha Irving, Andrew Bush, Jane C. Davies
      ERJ Open Res 5: 00234-2018; DOI: 10.1183/23120541.00234-2018 Published 4 November 2019
    • Open Access
      Impact of Achromobacter xylosoxidans isolation on the respiratory function of adult patients with cystic fibrosis
      Macha Tetart, Frederic Wallet, Maeva Kyheng, Sylvie Leroy, Thierry Perez, Olivier Le Rouzic, Benoit Wallaert, Anne Prevotat
      ERJ Open Res 5: 00051-2019; DOI: 10.1183/23120541.00051-2019 Published 8 December 2019
  • Asthma

    • Open Access
      Prevalence of oral corticosteroid use in the German severe asthma population
      Christian Taube, Peter Bramlage, Annette Hofer, Dörte Anderson
      ERJ Open Res 5: 00092-2019; DOI: 10.1183/23120541.00092-2019 Published 30 October 2019
    • Open Access
      FASE-CPHG study: a panoramic snapshot of difficult-to-treat, severe asthma in French nonacademic hospitals
      Laurent Portel, Eric Parrat, Cécilia Nocent-Ejnaini, Gilles Mangiapan, Anne Prud'homme, Jean-Philippe Oster, Corinne Aperre de Vecchi, Cyril Maurer, Chantal Raherison, Didier Debieuvre
      ERJ Open Res 5: 00069-2019; DOI: 10.1183/23120541.00069-2019 Published 30 October 2019
    • Open Access
      Real-life effectiveness of omalizumab in difficult-to-treat versus severe asthma: a national cohort study in Belgium
      Katia M.C. Verhamme, Catherine Lucet, Alain Van Meerhaeghe, Guy G.O. Brusselle, Marie-Laurence Lambert
      ERJ Open Res 5: 00253-2018; DOI: 10.1183/23120541.00253-2018 Published 25 November 2019
    • Open Access
      Sex differences in health services and medication use among older adults with asthma
      Teresa To, Natasha Gray, Kandace Ryckman, Jingqin Zhu, Ivy Fong, Andrea Gershon
      ERJ Open Res 5: 00242-2019; DOI: 10.1183/23120541.00242-2019 Published 2 December 2019
    • Open Access
      Efficacy of azithromycin in severe asthma from the AMAZES randomised trial
      Peter G. Gibson, Ian A. Yang, John W. Upham, Paul N. Reynolds, Sandra Hodge, Alan L. James, Christine Jenkins, Matthew J. Peters, Guy B. Marks, Melissa Baraket, Heather Powell, Jodie L. Simpson
      ERJ Open Res 5: 00056-2019; DOI: 10.1183/23120541.00056-2019 Published 23 December 2019
  • Bronchiectasis

    • Open Access
      Recommendations for travelling with bronchiectasis: a joint ELF/EMBARC/ERN-Lung collaboration
      Michal Shteinberg, Barbara Crossley, Tal Lavie, Sima Nadler, Jeanette Boyd, Felix C. Ringshausen, Tim Aksamit, James D. Chalmers, Pieter Goeminne
      ERJ Open Res 5: 00113-2019; DOI: 10.1183/23120541.00113-2019 Published 30 October 2019
    • Open Access
      Predictors of non-cystic fibrosis bronchiectasis in Indigenous adult residents of central Australia: results of a case–control study
      Lloyd Einsiedel, Hai Pham, Virginia Au, Saba Hatami, Kim Wilson, Tim Spelman, Hubertus Jersmann
      ERJ Open Res 5: 00001-2019; DOI: 10.1183/23120541.00001-2019 Published 2 December 2019
  • Lung transplantation

    • Open Access
      Pregnancy after lung and heart–lung transplantation: a French multicentre retrospective study of 39 pregnancies
      Charlotte Bry, Dominique Hubert, Martine Reynaud-Gaubert, Claire Dromer, Hervé Mal, Antoine Roux, Véronique Boussaud, Johanna Claustre, Jérôme Le Pavec, Muriel Murris-Espin, Isabelle Danner-Boucher
      ERJ Open Res 5: 00254-2018; DOI: 10.1183/23120541.00254-2018 Published 30 October 2019
  • COPD

    • Open Access
      Behavioural interventions targeting physical activity improve psychocognitive outcomes in COPD
      Kim L. Lavoie, Maria Sedeno, Alan Hamilton, Pei-Zhi Li, Dorothy De Sousa, Thierry Troosters, François Maltais, Jean Bourbeau
      ERJ Open Res 5: 00013-2019; DOI: 10.1183/23120541.00013-2019 Published 4 November 2019
    • Open Access
      Isolating peripheral effects of endogenous opioids in modulating exertional breathlessness in people with moderate or severe COPD: a randomised controlled trial
      David C. Currow, Toby Hunt, Sandra Louw, Danny Eckert, Peter Allcroft, Tim H.M. To, Aine Greene, Malgorzata Krajnik, Don Mahler, Magnus Ekström
      ERJ Open Res 5: 00153-2019; DOI: 10.1183/23120541.00153-2019 Published 23 December 2019
  • Respiratory infections

    • Open Access
      Changing epidemiology of nontuberculous mycobacterial lung disease over the last two decades in a region of the Basque country
      Sandra Pedrero, Eva Tabernero, Eunate Arana-Arri, Elena Urra, Maialen Larrea, Rafael Zalacain
      ERJ Open Res 5: 00110-2018; DOI: 10.1183/23120541.00110-2018 Published 4 November 2019
    • Open Access
      Association of atypical antipsychotics and mortality for patients hospitalised with pneumonia
      Zachary Boivin, Mario F. Perez, Nkiruka C. Atuegwu, Mark Metersky, Carlos A. Alvarez, Antonio Anzueto, Eric M. Mortensen
      ERJ Open Res 5: 00223-2018; DOI: 10.1183/23120541.00223-2018 Published 4 November 2019
  • Pulmonary vascular disease

    • Open Access
      Plasma receptor tyrosine kinase RET in pulmonary arterial hypertension diagnosis and differentiation
      Joanna Säleby, Habib Bouzina, Salaheldin Ahmed, Jakob Lundgren, Göran Rådegran
      ERJ Open Res 5: 00037-2019; DOI: 10.1183/23120541.00037-2019 Published 15 November 2019
  • Lung function

    • Open Access
      Prognostic significance of pulmonary function tests in dyskeratosis congenita, a telomere biology disorder
      Neelam Giri, Sandhiya Ravichandran, Youjin Wang, Shahinaz M. Gadalla, Blanche P. Alter, Joseph Fontana, Sharon A. Savage
      ERJ Open Res 5: 00209-2019; DOI: 10.1183/23120541.00209-2019 Published 15 November 2019
    • Open Access
      Comparison of oscillometry devices using active mechanical test loads
      Ronald J. Dandurand, Jean-Pierre Lavoie, Larry C. Lands, Zoltán Hantos, the Oscillometry Harmonisation Study Group
      ERJ Open Res 5: 00160-2019; DOI: 10.1183/23120541.00160-2019 Published 23 December 2019
  • Snus and infant birth size

    • Open Access
      Snus in pregnancy and infant birth size: a mother–child birth cohort study
      Ina Kreyberg, Katarina Hilde, Karen Eline S. Bains, Kai-Håkon Carlsen, Berit Granum, Guttorm Haugen, Gunilla Hedlin, Christine M. Jonassen, Live S. Nordhagen, Björn Nordlund, Corina S. Rueegg, Katrine D. Sjøborg, Håvard O. Skjerven, Anne C. Staff, Riyas Vettukattil, Karin C. Lødrup Carlsen, the PreventADALL Study Group
      ERJ Open Res 5: 00255-2019; DOI: 10.1183/23120541.00255-2019 Published 2 December 2019
  • Cough

    • Open Access
      Efficacy of two dosing schemes of a liquid containing ivy leaves dry extract EA 575 versus placebo in the treatment of acute bronchitis in adults
      Axel Schaefer, Fanny Ludwig, Bruno M. Giannetti, Michael Bulitta, Anja Wacker
      ERJ Open Res 5: 00019-2019; DOI: 10.1183/23120541.00019-2019 Published 8 December 2019
    • Open Access
      Prevalence of chronic wet cough and protracted bacterial bronchitis in Aboriginal children
      Pamela Laird, James Totterdell, Roz Walker, Anne B. Chang, André Schultz
      ERJ Open Res 5: 00248-2019; DOI: 10.1183/23120541.00248-2019 Published 8 December 2019
  • Pulmonary rehabilitation

    • Open Access
      Prevalence of comorbidities and impact on pulmonary rehabilitation outcomes
      Stacey J. Butler, Lok Sze Katrina Li, Lauren Ellerton, Andrea S. Gershon, Roger S. Goldstein, Dina Brooks
      ERJ Open Res 5: 00264-2019; DOI: 10.1183/23120541.00264-2019 Published 8 December 2019
  • Lung cancer

    • Open Access
      Tumour growth rate as a tool for response evaluation during PD-1 treatment for non-small cell lung cancer: a retrospective analysis
      Deirdre M.H.J. ten Berge, Daniel P. Hurkmans, Ilse den Besten, Jeroen S. Kloover, Ron H.J. Mathijssen, Reno Debets, Egbert F. Smit, Joachim G.J.V. Aerts
      ERJ Open Res 5: 00179-2019; DOI: 10.1183/23120541.00179-2019 Published 16 December 2019
  • E-cigarettes

    • Open Access
      Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries
      Kameshwar P. Singh, Gina Lawyer, Thivanka Muthumalage, Krishna P. Maremanda, Naushad Ahmad Khan, Samantha R. McDonough, Dongxia Ye, Scott McIntosh, Irfan Rahman
      ERJ Open Res 5: 00182-2019; DOI: 10.1183/23120541.00182-2019 Published 23 December 2019

Original research letters

  • Open Access
    Occult malignancy underlying a case of “hyperacute” onset of severe pulmonary hypertension
    Maria Rosaria Gioia, Uberto Maccari, Luca Marchetti, Enivarco Maglioni, Giuseppina Ciarleglio, Valentina Granese, Laura Salerno, Luigi Spagnoli, Ilenia Zanellato, Maria Raffaella Ambrosio, Andrea Bianco, Raffaele Scala
    ERJ Open Res 5: 00157-2019; DOI: 10.1183/23120541.00157-2019 Published 15 October 2019
  • Open Access
    Effect of facial skin cooling induced by a handheld fan on the cough reflex threshold and urge to cough induced by citric acid
    Masashi Kanezaki, Satoru Ebihara
    ERJ Open Res 5: 00089-2019; DOI: 10.1183/23120541.00089-2019 Published 15 October 2019
  • Open Access
    Assessing small airways dysfunction in asthma, asthma remission and healthy controls using particles in exhaled air
    Orestes A. Carpaij, Susan Muiser, Alex J. Bell, Huib A.M. Kerstjens, Craig J. Galban, Aleksa B. Fortuna, Salman Siddiqui, Anna-Carin Olin, Martijn C. Nawijn, Maarten van den Berge
    ERJ Open Res 5: 00202-2019; DOI: 10.1183/23120541.00202-2019 Published 21 October 2019
  • Open Access
    Occupational exposures and asthma–COPD overlap in a clinical cohort of adult-onset asthma
    Minna Tommola, Pinja Ilmarinen, Leena E. Tuomisto, Lauri Lehtimäki, Hannu Kankaanranta
    ERJ Open Res 5: 00191-2019; DOI: 10.1183/23120541.00191-2019 Published 21 October 2019
  • Open Access
    De novo bronchiectasis in haematological malignancies: patient characteristics, risk factors and survival
    Ricardo J. José, Jocelin Hall, Jeremy S. Brown
    ERJ Open Res 5: 00166-2019; DOI: 10.1183/23120541.00166-2019 Published 4 November 2019
  • Open Access
    Asthma and body mass definitions affect estimates of association: evidence from a community-based cross-sectional survey
    Francisca de Castro Mendes, Inês Paciência, João Cavaleiro Rufo, Diana Silva, Pedro Cunha, Mariana Farraia, Luís Delgado, Pedro Moreira, André Moreira
    ERJ Open Res 5: 00076-2019; DOI: 10.1183/23120541.00076-2019 Published 4 November 2019
  • Open Access
    Cholinergic synapse pathway gene polymorphisms associated with allergen-induced late asthmatic responses
    Ashwini Rajasekaran, Daniel He, Alice Yue, Amrit Singh, Casey P. Shannon, J. Mark FitzGerald, Louis-Philippe Boulet, Paul M. O'Byrne, Gail M. Gauvreau, Scott J. Tebbutt
    ERJ Open Res 5: 00107-2019; DOI: 10.1183/23120541.00107-2019 Published 4 November 2019
  • Open Access
    A systematic evaluation of the diagnostic criteria for COPD and exacerbations used in randomised controlled trials on the management of COPD exacerbations
    Alexander G. Mathioudakis, Julie Janner, Mia Moberg, Pablo Alonso-Coello, Jørgen Vestbo
    ERJ Open Res 5: 00136-2019; DOI: 10.1183/23120541.00136-2019 Published 15 November 2019
  • Open Access
    The obesity paradox in pulmonary arterial hypertension: the Scottish perspective
    Luke Lawson McLean, Katherine Pellino, Melanie Brewis, Andrew Peacock, Martin Johnson, Alistair Colin Church
    ERJ Open Res 5: 00241-2019; DOI: 10.1183/23120541.00241-2019 Published 25 November 2019
  • Open Access
    Rapid and sustained airway control in metastatic malignant melanoma: a case report
    Sarah Cullivan, John Bruzzi, Teresa McHale, Ramadan Shatwan, Paul Donnellan, David P. Breen
    ERJ Open Res 5: 00050-2019; DOI: 10.1183/23120541.00050-2019 Published 2 December 2019
  • Open Access
    Suppression of FENO with observed inhaled corticosteroid therapy in severe asthma: is it a useful test in clinical practice?
    Shoaib Faruqi, Sean Zhou, Joanne Thompson, Terry Robinson, Karen Watkins, Helena Cummings, Nicola Jackson, Anoop Prakash, Michael Crooks
    ERJ Open Res 5: 00123-2019; DOI: 10.1183/23120541.00123-2019 Published 25 November 2019
  • Open Access
    Serum levels of L1-ORF1p and airflow limitation
    Stefano Guerra, Monica M. Vasquez, Pasano Bojang, Irma N. Ramos, Duane L. Sherrill, Fernando D. Martinez, Marilyn Halonen, Kenneth S. Ramos
    ERJ Open Res 5: 00247-2018; DOI: 10.1183/23120541.00247-2018 Published 25 November 2019
  • Open Access
    Factors predicting progression of exercise training loads in people with interstitial lung disease
    Atsuhito Nakazawa, Leona M. Dowman, Narelle S. Cox, Christine F. McDonald, Catherine J. Hill, Annemarie L. Lee, Anne E. Holland
    ERJ Open Res 5: 00245-2018; DOI: 10.1183/23120541.00245-2018 Published 8 December 2019
  • Open Access
    Understanding the mechanism of bronchial thermoplasty using airway volume assessed by computed tomography
    David Langton, Peter B. Noble, Frank Thien, Graham M. Donovan
    ERJ Open Res 5: 00272-2019; DOI: 10.1183/23120541.00272-2019 Published 23 December 2019

Correspondence

  • Open Access
    SAPS3-CNIV score to predict hospital mortality following noninvasive ventilation: methodology insights
    Jun Duan, Bushra Mina, Antonio M. Esquinas
    ERJ Open Res 5: 00143-2019; DOI: 10.1183/23120541.00143-2019 Published 23 December 2019
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  • Study protocols
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    • Tuberculosis
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    • Asthma
    • Bronchiectasis
    • Lung transplantation
    • COPD
    • Respiratory infections
    • Pulmonary vascular disease
    • Lung function
    • Snus and infant birth size
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