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International guidelines on stage III N2 nonsmall cell lung cancer: surgery or radiotherapy?

Paul Martin Putora, Pawel Leskow, Fiona McDonald, Tim Batchelor, Matthiew Evison
ERJ Open Research 2020 6: 00159-2019; DOI: 10.1183/23120541.00159-2019
Paul Martin Putora
1Dept of Radiation Oncology, Kantonsspital St Gallen, St Gallen, Switzerland
2Dept of Radiation Oncology, University of Bern, Bern, Switzerland
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Pawel Leskow
3Dept of Thoracic Surgery, Kantonsspital St Gallen, St Gallen, Switzerland
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  • For correspondence: leskowpj@yahoo.de
Fiona McDonald
4Dept of Radiotherapy, The Royal Marsden NHS Foundation Trust, London, UK
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Tim Batchelor
5Dept of Thoracic Surgery, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
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Matthiew Evison
6Manchester Thoracic Oncology Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK
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  • FIGURE 1
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    FIGURE 1

    Example of the simplified decision tree representing the 2010 British Thoracic Society guideline. Pot.: potentially; LN: lymph node; RT: radiotherapy; S: surgery.

  • FIGURE 2
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    FIGURE 2

    Demonstration of all combinations of simplified criteria. Pot.: potentially; LN: lymph node; RT: radiotherapy; NP: no preference; S: surgery.

  • FIGURE 3
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    FIGURE 3

    Demonstration of the majority recommendations for each parameter combination. Pot.: potentially; LN: lymph node; RT: radiotherapy; NP: no preference; no consensus: a majority preference among the three options was not identified (four recommended surgery, two RT and four declared NP).

Tables

  • Figures
  • TABLE 1

    The use of simplified decision criteria per analysed guideline

    CriterionACCPBTSESMONICENCCNSEOMGermanChineseIrishAustralian
    Resectability••••••••••
    Lymph node volume•••••••
    Lymph node extent••••••

    ACCP: American College of Chest Physicians; BTS: British Thoracic Society; ESMO: European Society for Medical Oncology; NICE: National Institute for Health and Care Excellence; NCCN: National Comprehensive Cancer Network; SEOM: Spanish Society of Medical Oncology.

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    Vol 6 Issue 1 Table of Contents
    ERJ Open Research: 6 (1)
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    International guidelines on stage III N2 nonsmall cell lung cancer: surgery or radiotherapy?
    Paul Martin Putora, Pawel Leskow, Fiona McDonald, Tim Batchelor, Matthiew Evison
    ERJ Open Research Jan 2020, 6 (1) 00159-2019; DOI: 10.1183/23120541.00159-2019

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    International guidelines on stage III N2 nonsmall cell lung cancer: surgery or radiotherapy?
    Paul Martin Putora, Pawel Leskow, Fiona McDonald, Tim Batchelor, Matthiew Evison
    ERJ Open Research Jan 2020, 6 (1) 00159-2019; DOI: 10.1183/23120541.00159-2019
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