Tables
- TABLE 1
Characteristics of subjects and maternal folic acid supplementation, China, 1993–1995
Characteristics Folic acid users Non-users p-value Subjects 4542 4548 Age at child birth years 24.8±2.5 25.9±3.5 <0.001 Only child 4104 (90.5) 3545 (78.0) <0.001 Education Senior high school or more 1025 (24.5) 1214 (28.6) <0.001 Junior high school 2325 (55.6) 2012 (47.4) Primary school or less 829 (19.8) 1022 (24.1) Occupation Farmer 1579 (34.8) 1585 (34.9) 0.001 Factory worker 1771 (39.0) 1615 (35.5) Other or unknown 1192 (26.2) 1348 (29.6) Sex of infant Male 2382 (52.4) 2390 (52.6) 0.919 Female 2160 (47.6) 2158 (47.4) Data are presented as n, mean±sd or n (%), unless otherwise stated. Values for some characteristics may not be equal to total numbers in each group because of missing values.
- TABLE 2
Rate of allergic symptoms, asthma and hospitalisation due to asthma among offspring by maternal folic acid supplementation, China, 2000–2001
Folic acid p-value Total Yes No Subjects 4542 4548 9090 Allergic symptoms 70 (1.54) 93 (2.04) 0.070 163 (1.79) Asthma 42 (0.92) 40 (0.88) 0.820 82 (0.90) Hospitalisation due to asthma 11 (0.24) 16 (0.35) 0.337 27 (0.30) Data are presented as n or n (%), unless otherwise stated.
- TABLE 3
Compliance of maternal folic acid supplementation and risk for allergic symptoms, asthma and hospitalisation due to asthma in offspring, 2000–2001 n (%)
Folic acid Compliance# Periconception Preconception Postconception p Value Not compliant (340) Compliant (3354) p Value Subjects 2360 229 1101 340 3354 Allergic symptoms 28 (1.19) 5 (2.18) 18 (1.63) 0.384 3 (0.88) 48 (1.43) 0.443 Asthma 15 (0.64) 1 (0.44) 10 (0.91) 0.765 4 (1.18) 22 (0.66) 0.522 Hospitalisation due to asthma 4 (0.17) 2 (0.87) 10 (0.91) 0.479 0 (0) 4 (0.12) 0.565 Data are presented as n or n (%), unless otherwise stated. Values for some characteristics may not be equal to total numbers in each group because of missing values. #: Compliance was calculated as actual consumed pills divided by expected pills, compliant refers to compliance >80% and not compliant refers to compliance <80%.
- TABLE 4
Odds ratio of allergic symptoms, asthma and hospitalisation due to asthma among offspring by maternal folic acid supplementation, China, 2000–2001
Disease Unadjusted odds ratio (95% CI) Adjusted odds ratio (95% CI)# Allergic symptoms 0.75 (0.55–1.03) 0.80 (0.58–1.11) Asthma 1.05 (0.68–1.63) 1.04 (0.67–1.61) Hospitalisation due to asthma 0.69 (0.32–1.48) 0.79 (0.35–1.77) #: Adjusted by age, only-child, education and occupation.
Supplementary Materials
Supplementary Material
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Supplementary material 00250-2019.SUPPLEMENT
