Extract
Does it matter if a patient presenting with an exacerbation of COPD (ECOPD) is found to have consolidation on imaging? In the 2010 European COPD Audit, which included 14 111 patients from 384 hospitals in 13 countries with a primary discharge diagnosis of ECOPD, ∼20% had concomitant consolidation on admission chest radiography [1]. Crucially, the presence of consolidation was associated with increased 90-day mortality in this cohort (adjusted OR 1.36, 95% CI 1.2–1.55) [1]. Similar findings were seen in the large 2014 UK National COPD Audit, which found that ECOPD patients with consolidation experienced increased in-hospital mortality (6.7% versus 3.6%, p<0.001) and increased 90-day mortality (15.9% versus 10.8%, p<0.001) compared to patients without consolidation [2].
Abstract
It is vital that clinicians identify radiological consolidation in hospitalised COPD patients, as this confers an increased mortality risk, has important implications for risk stratification and influences management http://bit.ly/2q2vH2J
Footnotes
Conflict of interest: S.P. Trethewey has nothing to disclose.
Conflict of interest: J.R. Hurst reports support to attend meetings, and payments to himself and to University College London for educational activity and advisory work from pharmaceutical companies that make medicines to treat COPD, outside the submitted work.
Conflict of interest: A.M. Turner reports a research grant for a related systematic review from Grifols Biotherapeutics, research grants for studies in AATD from the Alpha 1 Foundation, personal fees for consultancy work from CSL Behring, and a grant for work in AATD liver disease and expenses to present trial data from Arrowhead Inc., outside the submitted work.
- Received October 16, 2019.
- Accepted November 20, 2019.
- Copyright ©ERS 2020
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