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Idiopathic pulmonary fibrosis: airway volume measurement identifies progressive disease on computed tomography scans

Thomas McLellan, Peter M. George, Paul Ford, Jan De Backer, Cedric Van Holsbeke, Benjamin Mignot, Nicholas J. Screaton, Alessandro Ruggiero, Muhunthan Thillai
ERJ Open Research 2020 6: 00290-2019; DOI: 10.1183/23120541.00290-2019
Thomas McLellan
1Royal Papworth Hospital, Cambridge, UK
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Peter M. George
2Royal Brompton Hospital, London, UK
3National Heart and Lung Institute, Imperial College London, London, UK
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Paul Ford
4Galapagos NV, Mechelen, Belgium
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Jan De Backer
5Fluidda NV, Antwerp, Belgium
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Cedric Van Holsbeke
5Fluidda NV, Antwerp, Belgium
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  • ORCID record for Cedric Van Holsbeke
Benjamin Mignot
5Fluidda NV, Antwerp, Belgium
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Nicholas J. Screaton
1Royal Papworth Hospital, Cambridge, UK
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Alessandro Ruggiero
1Royal Papworth Hospital, Cambridge, UK
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Muhunthan Thillai
1Royal Papworth Hospital, Cambridge, UK
6Dept of Medicine, University of Cambridge, Cambridge, UK
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  • For correspondence: muhunthan.thillai@nhs.net
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    FIGURE 1

    a) Specific airway volume change between computed tomography scans in an example patient. b) Median change in specific airway volume in the stable and progressive groups. The error bars represent the interquartile range and the bars themselves the median change. c) Correlation between absolute decline in forced vital capacity (FVC) (% predicted) with change in total specific airway volume.

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ERJ Open Research: 6 (1)
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Idiopathic pulmonary fibrosis: airway volume measurement identifies progressive disease on computed tomography scans
Thomas McLellan, Peter M. George, Paul Ford, Jan De Backer, Cedric Van Holsbeke, Benjamin Mignot, Nicholas J. Screaton, Alessandro Ruggiero, Muhunthan Thillai
ERJ Open Research Jan 2020, 6 (1) 00290-2019; DOI: 10.1183/23120541.00290-2019

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Idiopathic pulmonary fibrosis: airway volume measurement identifies progressive disease on computed tomography scans
Thomas McLellan, Peter M. George, Paul Ford, Jan De Backer, Cedric Van Holsbeke, Benjamin Mignot, Nicholas J. Screaton, Alessandro Ruggiero, Muhunthan Thillai
ERJ Open Research Jan 2020, 6 (1) 00290-2019; DOI: 10.1183/23120541.00290-2019
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