Tables
- TABLE 1
Risk of COPD in relation to overweight status at childhood and at young adult age
Childhood/young adult overweight status Cases of COPD HR (95% CI) Base model Normal weight/normal weight (n=33 514) 585 Ref. Overweight/normal weight (n=1368) 23 1.00 (0.66–1.51) Normal weight/overweight (n=1799) 47 1.72 (1.28–2.32) Overweight/overweight (n=989) 17 1.08 (0.67–1.75) Model adjusted for education level Normal weight/normal weight (n=32 523) 585 Ref. Overweight/normal weight (n=1334) 23 1.13 (0.75–1.72) Normal weight/overweight (n=1753) 47 1.52 (1.12–2.04) Overweight/overweight (n=961) 17 1.02 (0.63–1.65) Model adjusted for birthweight Normal weight/normal weight (n=31 714) 542 Ref. Overweight/normal weight (n=1292) 21 1.05 (0.68–1.63) Normal weight/overweight (n=1713) 42 1.67 (1.22–2.29) Overweight/overweight (n=941) 16 1.12 (0.68–1.84) Subcohort with Sweden as country of birth Normal weight/normal weight (n=27 979) 496 Ref. Overweight/normal weight (n=1138) 20 1.03 (0.66–1.61) Normal weight/overweight (n=1469) 40 1.72 (1.25–2.37) Overweight/overweight (n=821) 12 0.92 (0.52–1.63) Hazard Ratios (HRs) for COPD were calculated using Cox proportional hazards regression. All models were adjusted for birth year and country of birth. Base model: entire cohort, n=37 670). Model adjusted for maximal education level: n=36 571; categorised as low (n=6647, 17.6%), medium (n=16 213, 43.0%) or high (n=13 711, 36.4%). Model adjusted for birthweight: n=35 660. Subcohort of subjects born in Sweden and with parents born in Sweden: n=31 407. Normal weight/normal weight: not overweight at 8 or 20 years of age; overweight/normal weight: overweight at 8 but not at 20 years of age; normal weight/overweight: overweight at 20 but not at 8 years of age; overweight/overweight: overweight both at 8 and 20 years of age. Childhood overweight at 8 years of age was defined as body mass index (BMI) ≥17.9 kg·m−2 while young adult overweight at 20 years of age was defined as BMI ≥25 kg·m−2.
