Tables
- TABLE 1
Baseline characteristics, patient-reported quality of life outcome comparisons, and LASSO predictor models of Chronic Respiratory Questionnaire (CRQ) domains
Parameter IPF Non-IPF p-value# Subjects n 53 114 Age years 71 (68–76) 68 (61–75) 0.006 Female sex 12 (23%) 56 (49%) 0.001 FVC % pred 71 (61–82) 68 (55–85) 0.642 DLCO % pred 46 (38–59) 50 (39–63) 0.214 Ever-smoker status 29 (55%) 60 (53%) 0.674 UIP radiological pattern on CT 47 (89%) 25 (22%) <0.0001 Reported symptom duration months 24 (10–53) 18 (8–42) 0.215 6MWT distance m 363 (297–385); (n=22) 347 (268–469); (n=34) 0.687 mMRC dyspnoea scale (0–4) 2 (1–3) 3 (1–3) 0.147 PANAS Positive Score 34 (28–37) 33 (27–38) 0.776 PANAS Negative Score 12 (11–17) 15 (12–20) 0.043 PANAS ratio >2.9 23 (44%) 30 (28%) 0.042 SMAS-30 Taking Initiatives subscore (0–100) 70 (60–84) 68 (56–84) 0.508 SMAS-30 Investment behaviour subscore (0–100) 68 (56–78) 64 (52–80) 0.797 SMAS-30 Self-efficacy subscore (0–100) 92 (84–100) 92 (82–100) 0.539 SMAS-30 Total (0–100) 70 (59–80) 68 (59–80) 0.802 CRQ Dyspnoea 5.8 (4.1–6.6) 5.2 (3.4–6.2) 0.165 CRQ Fatigue 4.5 (3.5–5.3) 4.0 (3.0–5.0) 0.068 CRQ Emotional subscale 5.3 (4.5–6.0) 5.0 (4.1–5.9) 0.104 CRQ Mastery 5.5 (4.5–6.3) 5.3 (4.0–6.3) 0.179 CRQ Emotional Function (1–7) 5 (4.5–6) 5 (4.1–5.9) 0.104 CRQ Physical score 5.3 (3.9–5.7) 4.7 (3.2–5.5) 0.057 Data are presented as median (interquartile range) or n (%), unless otherwise stated. IPF: idiopathic pulmonary fibrosis; FVC: forced vital capacity; DLCO: diffusion capacity for carbon monoxide; UIP: usual interstitial pneumonia; CT: computed tomography; 6MWT: 6-min walk test; mMRC: modified Medical Research Council; PANAS: positive and negative affect survey; SMAS-30: self-management assessment survey 30. #: comparison between IPF and non-IPF subjects.