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Proteomic profiling of peripheral blood and bronchoalveolar lavage fluid in interstitial lung diseases: an explorative study

Sebastian Majewski, Xingwu Zhou, Joanna Miłkowska-Dymanowska, Adam J. Białas, Wojciech J. Piotrowski, Andrei Malinovschi
ERJ Open Research 2021 7: 00489-2020; DOI: 10.1183/23120541.00489-2020
Sebastian Majewski
1Dept of Pneumology and Allergy, Medical University of Lodz, Lodz, Poland
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  • ORCID record for Sebastian Majewski
Xingwu Zhou
2Dept of Medical Sciences: Clinical Physiology, Uppsala University, Uppsala, Sweden
3Dept of Medical Sciences: Respiratory Medicine, Sleep and Allergy, Uppsala University, Uppsala, Sweden
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Joanna Miłkowska-Dymanowska
1Dept of Pneumology and Allergy, Medical University of Lodz, Lodz, Poland
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Adam J. Białas
4Dept of Pathobiology of Respiratory Diseases, Medical University of Lodz, Lodz, Poland
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Wojciech J. Piotrowski
1Dept of Pneumology and Allergy, Medical University of Lodz, Lodz, Poland
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Andrei Malinovschi
2Dept of Medical Sciences: Clinical Physiology, Uppsala University, Uppsala, Sweden
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  • ORCID record for Andrei Malinovschi
  • For correspondence: andrei.malinovschi@medsci.uu.se
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    FIGURE 1

    Differences in the expression levels of the 92 investigated proteins between the groups with idiopathic pulmonary fibrosis (IPF) and sarcoidosis expressed as regression coefficient (circle) and 95% confidence interval (line) in bronchoalveolar lavage fluid (BALF) (figure 2 displays the same data in serum). Significant differences (false discovery rate-corrected p-values <0.05) are plotted in red. If the confidence interval is on the right side of the dotted line (0) this means that subjects with IPF had higher levels of that protein than subjects with sarcoidosis. The list of the proteins can be found at https://www.olink.com/products/inflammation/

  • FIGURE 2
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    FIGURE 2

    Differences in the expression levels of the 92 investigated proteins between the groups with idiopathic pulmonary fibrosis (IPF) and sarcoidosis expressed as regression coefficient (circle) and 95% confidence interval (line) in serum. Significant differences (false discovery rate-corrected p-values <0.05) are plotted in red. If the confidence interval is on the right side of the dotted line (0) this means that subjects with IPF had higher levels of that protein than subjects with sarcoidosis. The list of the proteins can be found at https://www.olink.com/products/inflammation/

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Vol 7 Issue 1 Table of Contents
ERJ Open Research: 7 (1)
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Proteomic profiling of peripheral blood and bronchoalveolar lavage fluid in interstitial lung diseases: an explorative study
Sebastian Majewski, Xingwu Zhou, Joanna Miłkowska-Dymanowska, Adam J. Białas, Wojciech J. Piotrowski, Andrei Malinovschi
ERJ Open Research Jan 2021, 7 (1) 00489-2020; DOI: 10.1183/23120541.00489-2020

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Proteomic profiling of peripheral blood and bronchoalveolar lavage fluid in interstitial lung diseases: an explorative study
Sebastian Majewski, Xingwu Zhou, Joanna Miłkowska-Dymanowska, Adam J. Białas, Wojciech J. Piotrowski, Andrei Malinovschi
ERJ Open Research Jan 2021, 7 (1) 00489-2020; DOI: 10.1183/23120541.00489-2020
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