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Table of Contents

01 April 2021; volume 7, issue 2

Editorials

  • Open Access
    COVID-19 controversy: when to intubate?
    Alyn H Morice
    ERJ Open Res 7: 00185-2021; DOI: 10.1183/23120541.00185-2021 Published 6 April 2021
  • Open Access
    The benefits of pulmonary rehabilitation in patients with COVID-19
    Zhen-feng He, Nan-shan Zhong, Wei-jie Guan
    ERJ Open Res 7: 00212-2021; DOI: 10.1183/23120541.00212-2021 Published 31 May 2021
  • Open Access
    Lung volume reduction in real clinical practice
    Jorine E. Hartman, Dirk-Jan Slebos
    ERJ Open Res 7: 00258-2021; DOI: 10.1183/23120541.00258-2021 Published 7 June 2021

Reviews

  • Open Access
    Targeted therapy in eosinophilic chronic obstructive pulmonary disease
    Mathieu Fieldes, Chloé Bourguignon, Said Assou, Amel Nasri, Aurélie Fort, Isabelle Vachier, John De Vos, Engi Ahmed, Arnaud Bourdin
    ERJ Open Res 7: 00437-2020; DOI: 10.1183/23120541.00437-2020 Published 12 April 2021
  • Open Access
    SHARP: enabling generation of real-world evidence on a pan-European scale to improve the lives of individuals with severe asthma
    Job J.M.H. van Bragt, Susanne Hansen, Ratko Djukanovic, Elisabeth H.D. Bel, Anneke ten Brinke, Scott S. Wagers, Anke H. Maitland-van der Zee, Celeste Porsbjerg
    ERJ Open Res 7: 00064-2021; DOI: 10.1183/23120541.00064-2021 Published 19 April 2021
  • Open Access
    Nontuberculous mycobacterial pulmonary disease: an integrated approach beyond antibiotics
    Paola Faverio, Federica De Giacomi, Bruno Dino Bodini, Anna Stainer, Alessia Fumagalli, Francesco Bini, Fabrizio Luppi, Stefano Aliberti
    ERJ Open Res 7: 00574-2020; DOI: 10.1183/23120541.00574-2020 Published 24 May 2021
  • Open Access
    Safety data in randomised real-world evidence studies: Salford Lung Study learnings
    Catherine Harvey, Ashley Woodcock, Jørgen Vestbo, Courtney Crim, Lucy Frith, Nawar Diar Bakerly, John P. New, Claire Williams, Hanaa Elkhenini, Nasir Majeed, Glenn Cardwell, Susan Collier, Loretta Jacques, Joanne Fletcher
    ERJ Open Res 7: 00966-2020; DOI: 10.1183/23120541.00966-2020 Published 31 May 2021
  • Open Access
    Identification and treatment of T2-low asthma in the era of biologics
    Chris Kyriakopoulos, Athena Gogali, Konstantinos Bartziokas, Konstantinos Kostikas
    ERJ Open Res 7: 00309-2020; DOI: 10.1183/23120541.00309-2020 Published 7 June 2021
  • Open Access
    Endothelial dysfunction in COPD: a systematic review and meta-analysis of studies using different functional assessment methods
    Marieta P. Theodorakopoulou, Maria Eleni Alexandrou, Dimitra Rafailia Bakaloudi, Georgia Pitsiou, Ioannis Stanopoulos, Theodoros Kontakiotis, Afroditi K. Boutou
    ERJ Open Res 7: 00983-2020; DOI: 10.1183/23120541.00983-2020 Published 28 June 2021

Congress Highlights

  • Open Access
    ERS International Congress 2020: highlights from the Respiratory Infections assembly
    Stefan Frent, Cristina Calarasu, Kseniia Suska, Kateryna Gashynova, Holly Keir
    ERJ Open Res 7: 00091-2021; DOI: 10.1183/23120541.00091-2021 Published 19 April 2021
  • Open Access
    ERS International Congress 2020: highlights from the Clinical Techniques, Imaging and Endoscopy assembly
    Pia Iben Pietersen, Bibi Klap, Nicole Hersch, Christian B. Laursen, Simon Walsh, Jouke Annema, Daniela Gompelmann
    ERJ Open Res 7: 00118-2021; DOI: 10.1183/23120541.00118-2021 Published 31 May 2021

Study protocols

  • Open Access
    BronchUK: protocol for an observational cohort study and biobank in bronchiectasis
    Anthony De Soyza, Philip Mawson, Adam T. Hill, Stuart Elborn, Judy M. Bradley, Charles S. Haworth, R. Andres Floto, Robert Wilson, Michael R. Loebinger, Mary Carroll, Megan Crichton, James D. Chalmers, Anita Sullivan, Jeremy Brown, John R. Hurst, Jamie Duckers, Martin Kelly, John Steer, Tim Gatheral, Paul P. Walker, Craig Winstanley, Alistair McGuire, David Denning, Richard McNally
    ERJ Open Res 7: 00775-2020; DOI: 10.1183/23120541.00775-2020 Published 19 April 2021
  • Open Access
    Design and rationale of a randomised, double-blind trial of the efficacy and safety of pirfenidone in patients with fibrotic hypersensitivity pneumonitis
    Evans R. Fernández Pérez, James L. Crooks, Jeffrey J. Swigris, Joshua J. Solomon, Michael P. Mohning, Tristan J. Huie, Matthew Koslow, David A. Lynch, Steve D. Groshong, Kaitlin Fier
    ERJ Open Res 7: 00054-2021; DOI: 10.1183/23120541.00054-2021 Published 7 June 2021
  • Open Access
    Study design of a randomised, placebo-controlled trial of nintedanib in children and adolescents with fibrosing interstitial lung disease
    Robin Deterding, Matthias Griese, Gail Deutsch, David Warburton, Emily M. DeBoer, Steven Cunningham, Annick Clement, Nicolaus Schwerk, Kevin R. Flaherty, Kevin K. Brown, Florian Voss, Ulrike Schmid, Rozsa Schlenker-Herceg, Daniela Verri, Mihaela Dumistracel, Marilisa Schiwek, Susanne Stowasser, Kay Tetzlaff, Emmanuelle Clerisme-Beaty, Lisa R. Young
    ERJ Open Res 7: 00805-2020; DOI: 10.1183/23120541.00805-2020 Published 21 June 2021

Original articles

  • COVID-19

    • Open Access
      A randomised trial of Mycobacterium w in critically ill patients with COVID-19: ARMY-1
      Inderpaul Singh Sehgal, Randeep Guleria, Sarman Singh, Mohammad Sabah Siddiqui, Ritesh Agarwal
      ERJ Open Res 7: 00059-2021; DOI: 10.1183/23120541.00059-2021 Published 12 April 2021
    • Open Access
      Nicotine upregulates ACE2 expression and increases competence for SARS-CoV-2 in human pneumocytes
      Fabrizio Maggi, Alfredo Rosellini, Pietro Giorgio Spezia, Daniele Focosi, Lisa Macera, Michele Lai, Mauro Pistello, Antonio de Iure, Carlo Tomino, Stefano Bonassi, Patrizia Russo
      ERJ Open Res 7: 00713-2020; DOI: 10.1183/23120541.00713-2020 Published 12 April 2021
    • Open Access
      Recovery from COVID-19: a sprint or marathon? 6-month follow-up data from online long COVID-19 support group members
      Anouk W. Vaes, Yvonne M.J. Goërtz, Maarten Van Herck, Felipe V.C. Machado, Roy Meys, Jeannet M. Delbressine, Sarah Houben-Wilke, Swetlana Gaffron, Dieter Maier, Chris Burtin, Rein Posthuma, Nicole P.H. van Loon, Frits M.E. Franssen, Bita Hajian, Sami O. Simons, Job F.M. van Boven, Frederikus A. Klok, Bart Spaetgens, Claire M.H. Pinxt, Limmie Y.L. Liu, Geertjan Wesseling, Yvonne Spies, Herman Vijlbrief, Alex J. van ’t Hul, Daisy J.A. Janssen, Martijn A. Spruit
      ERJ Open Res 7: 00141-2021; DOI: 10.1183/23120541.00141-2021 Published 24 May 2021
    • Open Access
      Benefits of pulmonary rehabilitation in COVID-19: a prospective observational cohort study
      Rainer Gloeckl, Daniela Leitl, Inga Jarosch, Tessa Schneeberger, Christoph Nell, Nikola Stenzel, Claus F. Vogelmeier, Klaus Kenn, Andreas R. Koczulla
      ERJ Open Res 7: 00108-2021; DOI: 10.1183/23120541.00108-2021 Published 31 May 2021
    • Open Access
      The protective effect of SARS-CoV-2 antibodies in Scottish healthcare workers
      Hani Abo-Leyah, Stephanie Gallant, Diane Cassidy, Yan Hui Giam, Justin Killick, Beth Marshall, Gordon Hay, Caroline Snowdon, Eleanor J. Hothersall, Thomas Pembridge, Rachel Strachan, Natalie Gallant, Benjamin J. Parcell, Jacob George, Elizabeth Furrie, James D. Chalmers
      ERJ Open Res 7: 00080-2021; DOI: 10.1183/23120541.00080-2021 Published 7 June 2021
  • Critical care

    • Open Access
      Critical care outcomes in patients with pre-existing pulmonary hypertension: insights from the ASPIRE registry
      Kris Bauchmuller, Robin Condliffe, Jennifer Southern, Catherine Billings, Athanasios Charalampopoulos, Charlie A. Elliot, Abdul Hameed, David G. Kiely, Ian Sabroe, A.A. Roger Thompson, Ajay Raithatha, Gary H. Mills
      ERJ Open Res 7: 00046-2021; DOI: 10.1183/23120541.00046-2021 Published 6 April 2021
  • Noninvasive ventilation

    • Open Access
      REINVENT: ERS International survey on REstrictive thoracic diseases IN long term home noninvasive VENTilation
      Paola Pierucci, Claudia Crimi, Annalisa Carlucci, Giovanna E. Carpagnano, Jean-Paul Janssens, Manel Lujan, Alberto Noto, Peter J. Wijkstra, Wolfram Windisch, Raffaele Scala
      ERJ Open Res 7: 00911-2020; DOI: 10.1183/23120541.00911-2020 Published 19 April 2021
  • COPD

    • Open Access
      Dyspnoea and symptom burden in mild–moderate COPD: the Canadian Cohort Obstructive Lung Disease Study
      Mathew Cherian, Dennis Jensen, Wan C. Tan, Sara Mursleen, Emma C. Goodall, Gilbert A. Nadeau, Amnah M. Awan, Darcy D. Marciniuk, Brandie L. Walker, Shawn D. Aaron, Denis E. O'Donnell, Kenneth R. Chapman, François Maltais, Paul Hernandez, Don D. Sin, Andrea Benedetti, Jean Bourbeau
      ERJ Open Res 7: 00960-2020; DOI: 10.1183/23120541.00960-2020 Published 19 April 2021
    • Open Access
      Energy expenditure and physical activity in COPD by doubly labelled water method and an accelerometer
      Hideaki Sato, Hidetoshi Nakamura, Yuki Nishida, Toru Shirahata, Sanehiro Yogi, Tomoe Akagami, Machika Soma, Kaiji Inoue, Mamoru Niitsu, Tomohiko Mio, Tatsuyuki Miyashita, Makoto Nagata, Satoshi Nakae, Yosuke Yamada, Shigeho Tanaka, Fuminori Katsukawa
      ERJ Open Res 7: 00407-2020; DOI: 10.1183/23120541.00407-2020 Published 4 May 2021
    • Open Access
      Pleiotropic associations of heterozygosity for the SERPINA1 Z allele in the UK Biobank
      Katherine A. Fawcett, Kijoung Song, Guoqing Qian, Aliki-Eleni Farmaki, Richard Packer, Catherine John, Nick Shrine, Raquel Granell, Sue Ring, Nicholas J. Timpson, Laura M. Yerges-Armstrong, Richard Eastell, Louise V. Wain, Robert A. Scott, Martin D. Tobin, Ian P. Hall
      ERJ Open Res 7: 00049-2021; DOI: 10.1183/23120541.00049-2021 Published 10 May 2021
    • Open Access
      Airflow limitation and tongue microbiota in community-dwelling elderly individuals
      Toru Takeshita, Koichiro Matsumoto, Michiko Furuta, Satoru Fukuyama, Kenji Takeuchi, Hiroaki Ogata, Mikari Asakawa, Shinya Kageyama, Jun Hata, Toshiharu Ninomiya, Hiromasa Inoue, Yoshihisa Yamashita
      ERJ Open Res 7: 00616-2020; DOI: 10.1183/23120541.00616-2020 Published 24 May 2021
    • Open Access
      Treatable traits in an English cohort: prevalence and predictors of future decline in lung function and quality of life in COPD
      Muhammad Rehan Sarwar, Vanessa Marie McDonald, Michael John Abramson, Eldho Paul, Johnson George
      ERJ Open Res 7: 00934-2020; DOI: 10.1183/23120541.00934-2020 Published 31 May 2021
    • Open Access
      Lung volume reduction in emphysema: a pragmatic prospective cohort study
      Christophe Dooms, Astrid Blondeel, Laurens J. Ceulemans, Johan Coolen, Stephanie Everaerts, Heleen Demeyer, Thierry Troosters, Geert Verleden, Dirk Van Raemdonck, Wim Janssens
      ERJ Open Res 7: 00877-2020; DOI: 10.1183/23120541.00877-2020 Published 31 May 2021
    • Open Access
      Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial–mesenchymal transition
      Mathew Suji Eapen, Wenying Lu, Tillie L. Hackett, Gurpreet Kaur Singhera, Malik Q. Mahmood, Ashutosh Hardikar, Chris Ward, Eugene Haydn Walters, Sukhwinder Singh Sohal
      ERJ Open Res 7: 00876-2020; DOI: 10.1183/23120541.00876-2020 Published 7 June 2021
    • Open Access
      INTREPID: single- versus multiple-inhaler triple therapy for COPD in usual clinical practice
      David M.G. Halpin, Sally Worsley, Afisi S. Ismaila, Kai-Michael Beeh, Dawn Midwinter, Janwillem W.H. Kocks, Elaine Irving, Jose M. Marin, Neil Martin, Maggie Tabberer, Neil G. Snowise, Chris Compton
      ERJ Open Res 7: 00950-2020; DOI: 10.1183/23120541.00950-2020 Published 7 June 2021
    • Open Access
      Swallowing dysfunction in patients hospitalised due to a COPD exacerbation
      Margareta Gonzalez Lindh, Christer Janson, Monica Blom Johansson, Mimmi Jonsson, Emma Mälberg, Elina Allansson, Cecilia Holm, Margareta Jennische, Hirsch Koyi
      ERJ Open Res 7: 00173-2021; DOI: 10.1183/23120541.00173-2021 Published 7 June 2021
    • Open Access
      Effect of β-blockers on the risk of COPD exacerbations according to indication of use: the Rotterdam Study
      Leila Karimi, Lies Lahousse, Phebe De Nocker, Bruno H. Stricker, Guy G. Brusselle, Katia M.C. Verhamme
      ERJ Open Res 7: 00624-2020; DOI: 10.1183/23120541.00624-2020 Published 28 June 2021
  • Asthma

    • Open Access
      Asthma in South African adolescents: a time trend and risk factor analysis over two decades
      Cynthia B. Baard, Zoe Franckling-Smith, Jacinta Munro, Lesley Workman, Heather J. Zar
      ERJ Open Res 7: 00576-2020; DOI: 10.1183/23120541.00576-2020 Published 6 April 2021
    • Open Access
      Patients' experiences of asthma exacerbation and management: a qualitative study of severe asthma
      Woo-Jung Song, Ha-Kyeong Won, Suh Young Lee, Han-Ki Park, You Sook Cho, Kian Fan Chung, Liam G. Heaney, Woo Joung Joung
      ERJ Open Res 7: 00528-2020; DOI: 10.1183/23120541.00528-2020 Published 6 April 2021
    • Open Access
      “It's like being on a roller coaster”: the burden of caring for people with severe asthma
      Eleanor C. Majellano, Vanessa L. Clark, Juliet M. Foster, Peter G. Gibson, Vanessa M. McDonald
      ERJ Open Res 7: 00812-2020; DOI: 10.1183/23120541.00812-2020 Published 12 April 2021
    • Open Access
      Comparison of inhalation technique with the Diskus and Autohaler in asthmatic children at home
      Annelies van der Kolk, Natasja Lammers, Marjolein Brusse-Keizer, Job van der Palen, Joyce Faber, Reina Spenkelink-Visser, Bernard J. Thio
      ERJ Open Res 7: 00215-2019; DOI: 10.1183/23120541.00215-2019 Published 19 April 2021
    • You have accessRestricted access
      Anxiety disorders and asthma among adolescents in Uganda: role of early-life exposures
      Harriet Mpairwe, Richard Stephen Mpango, Wilber Sembajjwe, Emily L. Webb, Alison M. Elliott, Neil Pearce, Eugene Kinyanda
      ERJ Open Res 7: 00749-2020; DOI: 10.1183/23120541.00749-2020 Published 19 April 2021
    • Open Access
      Lung function improvements following inhaled indacaterol/glycopyrronium/mometasone furoate are independent of dosing time in asthma patients: a randomised trial
      Jutta Beier, Henrik Watz, Zuzana Diamant, Jens M. Hohlfeld, Dave Singh, Pascale Pinot, Ieuan Jones, Hanns-Christian Tillmann
      ERJ Open Res 7: 00425-2020; DOI: 10.1183/23120541.00425-2020 Published 19 April 2021
    • Open Access
      COL4A3 expression in asthmatic epithelium depends on intronic methylation and ZNF263 binding
      Sai Sneha Priya Nemani, Cornelis Joseph Vermeulen, Martin Pech, Alen Faiz, Brian George G. Oliver, Maarten van den Berge, Janette Kay Burgess, Matthias V. Kopp, Markus Weckmann
      ERJ Open Res 7: 00802-2020; DOI: 10.1183/23120541.00802-2020 Published 7 June 2021
    • Open Access
      Acute and durable effect of inhaled hypertonic saline on mucociliary clearance in adult asthma
      William D. Bennett, Allison Burbank, Martha Almond, Jihong Wu, Agathe Ceppe, Michelle Hernandez, Richard C. Boucher, David B. Peden
      ERJ Open Res 7: 00062-2021; DOI: 10.1183/23120541.00062-2021 Published 7 June 2021
  • Asthma and allergy

    • Open Access
      Contributions of asthma, rhinitis and IgE to exhaled nitric oxide in adolescents
      Bess M. Flashner, Sheryl L. Rifas-Shiman, Emily Oken, Carlos A. Camargo, Thomas A.E. Platts-Mills, Lisa Workman, Augusto A. Litonjua, Diane R. Gold, Mary B. Rice
      ERJ Open Res 7: 00945-2020; DOI: 10.1183/23120541.00945-2020 Published 19 April 2021
  • Allergy

    • Open Access
      Effect of fexofenadine hydrochloride on allergic rhinitis aggravated by air pollutants
      Anne K. Ellis, Margarita Murrieta-Aguttes, Sandy Furey, Pascaline Picard, Christopher Carlsten
      ERJ Open Res 7: 00806-2020; DOI: 10.1183/23120541.00806-2020 Published 6 April 2021
    • You have accessRestricted access
      Nasal upregulation of CST1 in dog-sensitised children with severe allergic airway disease
      Ulrika Käck, Elisabet Einarsdottir, Marianne van Hage, Anna Asarnoj, Anna James, Anna Nopp, Kaarel Krjutškov, Shintaro Katayama, Juha Kere, Gunnar Lilja, Cilla Söderhäll, Jon R. Konradsen
      ERJ Open Res 7: 00917-2020; DOI: 10.1183/23120541.00917-2020 Published 19 April 2021
  • Altitude

    • Open Access
      Pulmonary haemodynamic response to exercise in highlanders versus lowlanders
      Silvia Ulrich, Stéphanie Saxer, Michael Furian, Patrick R. Bader, Paula Appenzeller, Philipp M. Scheiwiller, Maamed Mademilov, Ulan Sheraliev, Felix Tanner, Talantbek M. Sooronbaev, Konrad E. Bloch, Mona Lichtblau
      ERJ Open Res 7: 00937-2020; DOI: 10.1183/23120541.00937-2020 Published 6 April 2021
  • Dyspnoea

    • Open Access
      Validity and reliability of the Multidimensional Dyspnoea Profile in older adults
      Eralda Hegendörfer, Alexander Doukhopelnikoff, Jean-Marie Degryse
      ERJ Open Res 7: 00606-2020; DOI: 10.1183/23120541.00606-2020 Published 12 April 2021
    • Open Access
      A common model for the breathlessness experience across cardiorespiratory disease
      Sarah L. Finnegan, Kyle T.S. Pattinson, Josefin Sundh, Magnus Sköld, Christer Janson, Anders Blomberg, Jacob Sandberg, Magnus Ekström
      ERJ Open Res 7: 00818-2020; DOI: 10.1183/23120541.00818-2020 Published 28 June 2021
  • Lung function

    • Open Access
      The differing physiology of nitrogen and tracer gas multiple-breath washout techniques
      Dominic Sandhu, Grant A.D. Ritchie, Peter A. Robbins
      ERJ Open Res 7: 00858-2020; DOI: 10.1183/23120541.00858-2020 Published 19 April 2021
    • Open Access
      Classifying signals from a wearable accelerometer device to measure respiratory rate
      Gordon B. Drummond, Darius Fischer, Margaret Lees, Andrew Bates, Janek Mann, D.K. Arvind
      ERJ Open Res 7: 00681-2020; DOI: 10.1183/23120541.00681-2020 Published 26 April 2021
    • Open Access
      Reference equations for tidal breathing parameters using structured light plethysmography
      Shayan Motamedi-Fakhr, Richard Iles, Nicki Barker, John Alexander, Brendan G. Cooper
      ERJ Open Res 7: 00050-2021; DOI: 10.1183/23120541.00050-2021 Published 7 June 2021
  • Cystic fibrosis

    • Open Access
      Cystic fibrosis airway microbiota associated with outcomes of nontuberculous mycobacterial infection
      Lindsay J. Caverly, Madsen Zimbric, Michelle Azar, Kristopher Opron, John J. LiPuma
      ERJ Open Res 7: 00578-2020; DOI: 10.1183/23120541.00578-2020 Published 19 April 2021
    • Open Access
      Lumacaftor/ivacaftor changes the lung microbiome and metabolome in cystic fibrosis patients
      Anne H. Neerincx, Katrine Whiteson, Joann L. Phan, Paul Brinkman, Mahmoud I. Abdel-Aziz, Els J.M. Weersink, Josje Altenburg, Christof J. Majoor, Anke H. Maitland-van der Zee, Lieuwe D.J. Bos
      ERJ Open Res 7: 00731-2020; DOI: 10.1183/23120541.00731-2020 Published 19 April 2021
    • Open Access
      Achromobacter xylosoxidans airway infection is associated with lung disease severity in children with cystic fibrosis
      Charlotte Marsac, Laura Berdah, Guillaume Thouvenin, Isabelle Sermet-Gaudelus, Harriet Corvol
      ERJ Open Res 7: 00076-2021; DOI: 10.1183/23120541.00076-2021 Published 31 May 2021
  • Pulmonary vascular disease

    • Open Access
      Rapid prediction of adverse outcomes for acute normotensive pulmonary embolism: derivation of the Calgary Acute Pulmonary Embolism score
      Kevin Solverson, Christopher Humphreys, Zhiying Liang, Graeme Prosperi-Porta, James E. Andruchow, Paul Boiteau, Andre Ferland, Eric Herget, Doug Helmersen, Jason Weatherald
      ERJ Open Res 7: 00879-2020; DOI: 10.1183/23120541.00879-2020 Published 19 April 2021
    • Open Access
      Prognostic value of right atrial dilation in patients with pulmonary embolism
      Markus H. Lerchbaumer, Matthias Ebner, Christian O. Ritter, Laura Steimke, Nina I.J. Rogge, Carmen Sentler, Aaron Thielmann, Lukas Hobohm, Karsten Keller, Joachim Lotz, Gerd Hasenfuß, Rolf Wachter, Bernd Hamm, Stavros V. Konstantinides, Galit Aviram, Mareike Lankeit
      ERJ Open Res 7: 00414-2020; DOI: 10.1183/23120541.00414-2020 Published 24 May 2021
    • Open Access
      Predicting mortality during long-term follow-up in pulmonary arterial hypertension
      David Kylhammar, Clara Hjalmarsson, Roger Hesselstrand, Kjell Jansson, Mohammad Kavianipour, Barbro Kjellström, Magnus Nisell, Stefan Söderberg, Göran Rådegran
      ERJ Open Res 7: 00837-2020; DOI: 10.1183/23120541.00837-2020 Published 31 May 2021
    • Open Access
      The isobaric pulmonary arterial compliance in pulmonary hypertension
      Denis Chemla, Emmanuelle Berthelot, Jason Weatherald, Edmund M. T. Lau, Laurent Savale, Antoine Beurnier, David Montani, Olivier Sitbon, Pierre Attal, David Boulate, Patrick Assayag, Marc Humbert, Philippe Hervé
      ERJ Open Res 7: 00941-2020; DOI: 10.1183/23120541.00941-2020 Published 31 May 2021
  • Sleep

    • Open Access
      Sleep apnoea and incident malignancy in type 2 diabetes
      Sarah Driendl, Michael Arzt, Claudia S. Zimmermann, Bettina Jung, Tobias Pukrop, Carsten A. Böger, Sebastian Haferkamp, Florian Zeman, Iris M. Heid, Stefan Stadler
      ERJ Open Res 7: 00036-2021; DOI: 10.1183/23120541.00036-2021 Published 4 May 2021
    • Open Access
      Participation in physical activity is associated with reduced nocturnal hypoxaemia in males
      David Stevens, Sarah Appleton, Yohannes Melaku, Sean Martin, Robert Adams, Gary Wittert
      ERJ Open Res 7: 00852-2020; DOI: 10.1183/23120541.00852-2020 Published 24 May 2021
  • Cough

    • Open Access
      Prevalence, incidence and characteristics of chronic cough among adults from the Canadian Longitudinal Study on Aging
      Imran Satia, Alexandra J. Mayhew, Nazmul Sohel, Om Kurmi, Kieran J. Killian, Paul M. O'Byrne, Parminder Raina
      ERJ Open Res 7: 00160-2021; DOI: 10.1183/23120541.00160-2021 Published 4 May 2021
  • Interstitial lung disease

    • Open Access
      Idiopathic pulmonary fibrosis cluster analysis highlights diagnostic delay and cardiovascular comorbidity association with outcome
      Jaume Bordas-Martínez, Ricard Gavaldà, Jessica G. Shull, Vanesa Vicens-Zygmunt, Lurdes Planas-Cerezales, Guadalupe Bermudo-Peloche, Salud Santos, Neus Salord, Carmen Monasterio, Maria Molina-Molina, Guillermo Suarez-Cuartin
      ERJ Open Res 7: 00897-2020; DOI: 10.1183/23120541.00897-2020 Published 10 May 2021
    • You have accessRestricted access
      Type 2 diabetes risk in sarcoidosis patients untreated and treated with corticosteroids
      Joshua P. Entrop, Susanna Kullberg, Johan Grunewald, Anders Eklund, Kerstin Brismar, Elizabeth V. Arkema
      ERJ Open Res 7: 00028-2021; DOI: 10.1183/23120541.00028-2021 Published 24 May 2021
    • You have accessRestricted access
      The Living with Pulmonary Fibrosis questionnaire in progressive fibrosing interstitial lung disease
      Jeffrey Swigris, Katelyn Cutts, Natalia Male, Michael Baldwin, Klaus B. Rohr, Donald M. Bushnell
      ERJ Open Res 7: 00145-2020; DOI: 10.1183/23120541.00145-2020 Published 24 May 2021
    • Open Access
      Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease
      Aernoud A. van Batenburg, Karin M. Kazemier, Matthijs F.M. van Oosterhout, Joanne J. van der Vis, Jan C. Grutters, Roel Goldschmeding, Coline H.M. van Moorsel
      ERJ Open Res 7: 00691-2020; DOI: 10.1183/23120541.00691-2020 Published 31 May 2021
    • Open Access
      Transition of patients with interstitial lung disease from paediatric to adult care
      Václav Koucký, Petr Pohunek, Martina Vašáková, Andrew Bush
      ERJ Open Res 7: 00964-2020; DOI: 10.1183/23120541.00964-2020 Published 7 June 2021
    • Open Access
      Spectrum of childhood interstitial and diffuse lung diseases at a tertiary hospital in Egypt
      Salma G. Abdelhady, Eman M. Fouda, Malak A. Shaheen, Faten A. Ghazal, Ahmed M. Mostafa, Ahmed M. Osman, Andrew G. Nicholson, Heba M. Hamza
      ERJ Open Res 7: 00880-2020; DOI: 10.1183/23120541.00880-2020 Published 7 June 2021
    • Open Access
      Anti-HSP47 siRNA lipid nanoparticle ND-L02-s0201 reverses interstitial pulmonary fibrosis in preclinical rat models
      Yun Liu, Jian Liu, Alistair Quimbo, Fengcheng Xia, Jiping Yao, Jean-Pierre Clamme, Sonya Zabludoff, Jun Zhang, Wenbin Ying
      ERJ Open Res 7: 00733-2020; DOI: 10.1183/23120541.00733-2020 Published 7 June 2021
    • Open Access
      Endobronchial autologous bone marrow–mesenchymal stromal cells in idiopathic pulmonary fibrosis: a phase I trial
      Arantza Campo, José María González-Ruiz, Enrique Andreu, Ana B. Alcaide, María M. Ocón, Juan De-Torres, Jesús Pueyo, Rosa Cordovilla, Eva Villaron, Fermín Sanchez-Guijo, Miguel Barrueco, Jorge Nuñez-Córdoba, Felipe Prósper, Javier J. Zulueta
      ERJ Open Res 7: 00773-2020; DOI: 10.1183/23120541.00773-2020 Published 28 June 2021
    • Open Access
      Body mass index and in-hospital mortality in patients with acute exacerbation of idiopathic pulmonary fibrosis
      Nobuyasu Awano, Taisuke Jo, Hideo Yasunaga, Minoru Inomata, Naoyuki Kuse, Mari Tone, Kojiro Morita, Hiroki Matsui, Kiyohide Fushimi, Takahide Nagase, Takehiro Izumo
      ERJ Open Res 7: 00037-2021; DOI: 10.1183/23120541.00037-2021 Published 28 June 2021
  • Respiratory infections

    • Open Access
      Influence of age, sex and respiratory viruses on the rates of emergency department visits and hospitalisations with respiratory tract infections, asthma and COPD
      Imran Satia, Adil Adatia, Ruth P. Cusack, Justina M. Greene, Paul M. O'Byrne, Kieran J. Killian, Neil Johnston
      ERJ Open Res 7: 00053-2021; DOI: 10.1183/23120541.00053-2021 Published 24 May 2021
    • Open Access
      Microbial and clinical factors are related to recurrence of symptoms after childhood lower respiratory tract infection
      Emma M. de Koff, Wing Ho Man, Marlies A. van Houten, Arine M. Vlieger, Mei Ling J.N. Chu, Elisabeth A.M. Sanders, Debby Bogaert
      ERJ Open Res 7: 00939-2020; DOI: 10.1183/23120541.00939-2020 Published 28 June 2021
  • Lung cancer

    • Open Access
      Excess mortality and undertreatment in elderly lung cancer patients: treatment nihilism in the modern era?
      Jonathan Pham, Matthew Conron, Gavin Wright, Paul Mitchell, David Ball, Jennifer Philip, Margaret Brand, John Zalcberg, Rob G. Stirling
      ERJ Open Res 7: 00393-2020; DOI: 10.1183/23120541.00393-2020 Published 24 May 2021
  • Bronchiectasis

    • Open Access
      Home-based pulmonary rehabilitation in people with bronchiectasis: a randomised controlled trial
      Anderson José, Anne E. Holland, Jessyca P.R. Selman, Cristiane Oliveira de Camargo, Diogo Simões Fonseca, Rodrigo A. Athanazio, Samia Z. Rached, Alberto Cukier, Rafael Stelmach, Simone Dal Corso
      ERJ Open Res 7: 00021-2021; DOI: 10.1183/23120541.00021-2021 Published 31 May 2021
  • Bronchoscopy

    • Open Access
      A randomised study of comfort during bronchoscopy comparing conscious sedation and anaesthetist-controlled general anaesthesia, including the utility of bispectral index monitoring
      Thomas R. Skinner, Joseph Churton, Timothy P. Edwards, Farzad Bashirzadeh, Christopher Zappala, Justin T. Hundloe, Hau Tan, Andrew J. Pattison, Maryann Todman, Gunter F. Hartel, David I. Fielding
      ERJ Open Res 7: 00895-2020; DOI: 10.1183/23120541.00895-2020 Published 31 May 2021
  • Paediatric pulmonology

    • Open Access
      Phagocyte extracellular traps in children with neutrophilic airway inflammation
      Paul T. King, Lovisa Dousha, Nadeene Clarke, Jennifer Schaefer, Rosemary Carzino, Roleen Sharma, Ken L. Wan, Aveena Anantharajah, Kim O'Sullivan, Zhong X. Lu, Stephen R. Holdsworth, Sarath Ranganathan, Philip G. Bardin, David S. Armstrong
      ERJ Open Res 7: 00883-2020; DOI: 10.1183/23120541.00883-2020 Published 21 June 2021
  • EILO

    • Open Access
      Characteristics and impact of exercise-induced laryngeal obstruction: an international perspective
      Emil S. Walsted, Bamidele Famokunwa, Louise Andersen, Sune L. Rubak, Frederik Buchvald, Lars Pedersen, James Dodd, Vibeke Backer, Kim G. Nielsen, Andrew Getzin, James H. Hull
      ERJ Open Res 7: 00195-2021; DOI: 10.1183/23120541.00195-2021 Published 28 June 2021

Original research letters

  • Open Access
    Pneumatocoeles after bronchoscopic lung volume reduction with valves
    Francois Lestelle, Romane Fumat, Alain Didier, Samia Collot, Thomas Egenod, Guillaume Faviez, Christophe Hermant, Gavin Plat, Nicolas Guibert
    ERJ Open Res 7: 00747-2020; DOI: 10.1183/23120541.00747-2020 Published 6 April 2021
  • Open Access
    Analysis of pathological changes in the epithelium in COVID-19 patient airways
    Wenguang Yin, Weitao Cao, Guangde Zhou, Lifei Wang, Jing Sun, Airu Zhu, Zhongfang Wang, Yumin Zhou, Xiaoqing Liu, Yimin Li, Nanshan Zhong, Jincun Zhao, Lei Liu, Pixin Ran
    ERJ Open Res 7: 00690-2020; DOI: 10.1183/23120541.00690-2020 Published 6 April 2021
  • Open Access
    High-dose glucocorticoid treatment of near-fatal bocavirus lung infection results in rapid recovery
    Matthias Obenaus, Oliver Schildgen, Dirk Schürmann, Ann-Christin von Brünneck, Martin Janz, Ulrich Keller, Bernhard Gebauer, Johannes Schilling, Stefan Schwartz, Benedikt Weissbrich, Thomas Schneider, Jörg Hofmann, Stephan Mathas
    ERJ Open Res 7: 00060-2021; DOI: 10.1183/23120541.00060-2021 Published 12 April 2021
  • Open Access
    Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
    Merel Jacobs, Lies Lahousse, Hannelore P. Van Eeckhoutte, Sara R.A. Wijnant, Joris R. Delanghe, Guy G. Brusselle, Ken R. Bracke
    ERJ Open Res 7: 00940-2020; DOI: 10.1183/23120541.00940-2020 Published 19 April 2021
  • Open Access
    Home parasternal electromyography tracks patient-reported and physiological measures of recovery from severe COPD exacerbation
    Rebecca Francesca D'Cruz, Eui-Sik Suh, Georgios Kaltsakas, Amy Dewar, Neeraj Mukesh Shah, Rita Priori, Abdel Douiri, Louise Rose, Nicholas Hart, Patrick Brian Murphy
    ERJ Open Res 7: 00709-2020; DOI: 10.1183/23120541.00709-2020 Published 26 April 2021
  • Open Access
    Detection of Cutibacterium acnes in granulomas of patients with either hypersensitivity pneumonitis or vasculitis reveals that its presence is not unique for sarcoidosis
    Els Beijer, Kees Seldenrijk, Bob Meek, Jan Damen, Marian J.R. Quanjel, Jan C. Grutters, Marcel Veltkamp
    ERJ Open Res 7: 00930-2020; DOI: 10.1183/23120541.00930-2020 Published 4 May 2021
  • Open Access
    Home-based pulmonary rehabilitation: an implementation study using the RE-AIM framework
    Janet Bondarenko, Chloe Babic, Angela T. Burge, Anne E. Holland
    ERJ Open Res 7: 00469-2020; DOI: 10.1183/23120541.00469-2020 Published 10 May 2021
  • Open Access
    Sputum production in chronic cough increases the probability of asthma: a cross-sectional questionnaire study
    Heikki O. Koskela, Anne M. Lätti
    ERJ Open Res 7: 00086-2021; DOI: 10.1183/23120541.00086-2021 Published 24 May 2021
  • Open Access
    Would it have happened without Christmas? Thoracic emphysema and allergic bronchopulmonary aspergillosis in a juvenile cystic fibrosis patient with the G551D mutation receiving ivacaftor
    Jochen G. Mainz, Nina Erdmann, Franziska Duckstein, Carlos Zagoya
    ERJ Open Res 7: 00758-2020; DOI: 10.1183/23120541.00758-2020 Published 24 May 2021
  • Open Access
    Airway smooth muscle cells from severe asthma patients with fixed airflow obstruction are responsive to steroid and bronchodilator treatment in vitro
    Sandra Rutting, Dia Xenaki, Karosham D. Reddy, Melissa Baraket, David G. Chapman, Gregory G. King, Brian G. Oliver, Katrina O. Tonga
    ERJ Open Res 7: 00117-2021; DOI: 10.1183/23120541.00117-2021 Published 31 May 2021
  • Open Access
    A review of physiotherapy practice for people with bronchiectasis
    Annemarie L. Lee, Susy Baenziger, Amanda Louey, Sophie Jennings, Peter Solin, Ryan Hoy
    ERJ Open Res 7: 00569-2020; DOI: 10.1183/23120541.00569-2020 Published 7 June 2021
  • Open Access
    Nasal airway epithelial repair after very preterm birth
    Jessica Hillas, Denby J. Evans, Sherlynn Ang, Thomas Iosifidis, Luke W. Garratt, Naomi Hemy, Elizabeth Kicic-Starcevich, Shannon J. Simpson, Anthony Kicic
    ERJ Open Res 7: 00913-2020; DOI: 10.1183/23120541.00913-2020 Published 7 June 2021
  • Open Access
    Comparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?
    Benedikt Ditz, Jeunard G. Boekhoudt, Hananeh Aliee, Fabian J. Theis, Martijn Nawijn, Corry-Anke Brandsma, Pieter S. Hiemstra, Wim Timens, Gaik W. Tew, Michele A. Grimbaldeston, Margaret Neighbors, Victor Guryev, Maarten van den Berge, Alen Faiz
    ERJ Open Res 7: 00104-2021; DOI: 10.1183/23120541.00104-2021 Published 21 June 2021
  • Open Access
    Pattern of cancer patient referral and organisational model of an interventional pulmonology programme during the COVID-19 pandemic
    Rocco Trisolini, Daniele Magnini, Vanina Livi, Fausto Leoncini, Lucia M. Porro, Maria C. Flore, Daniela Paioli, Giovanni Sotgiu
    ERJ Open Res 7: 00152-2021; DOI: 10.1183/23120541.00152-2021 Published 21 June 2021
  • Open Access
    Microparticles in COVID-19 as a link between lung injury extension and thrombosis
    Olivier Morel, Benjamin Marchandot, Laurence Jesel, Laurent Sattler, Antonin Trimaille, Anais Curtiaud, Mickael Ohana, Samira Fafi-Kremer, Valerie Schini-Kerth, Lelia Grunebaum, Jean-Marie Freyssinet
    ERJ Open Res 7: 00954-2020; DOI: 10.1183/23120541.00954-2020 Published 21 June 2021
  • Open Access
    Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products
    Alen Faiz, Senani N.H. Rathnayake, Nick H.T. ten Hacken, Victor Guryev, Maarten van den Berge, Simon D. Pouwels
    ERJ Open Res 7: 00947-2020; DOI: 10.1183/23120541.00947-2020 Published 28 June 2021

Correspondence

  • Open Access
    Confocal laser endomicroscopy to guide sampling of a pure ground-glass opacity
    Thibault Viatgé, Thomas Villeneuve, Dominique D'Aure, Julien Mazières, Gavin Plat, Christophe Hermant, Nicolas Guibert
    ERJ Open Res 7: 00910-2020; DOI: 10.1183/23120541.00910-2020 Published 6 April 2021
  • Open Access
    Conservative management of COVID-19 associated hypoxaemia
    Wolfram Windisch, Stefan Kluge, Martin Bachmann, Carl-Peter Criée, Steffen Weber-Carstens, Michael Westhoff, Christian Karagiannidis, Tobias Welte
    ERJ Open Res 7: 00113-2021; DOI: 10.1183/23120541.00113-2021 Published 6 April 2021
  • Open Access
    Conservative management of COVID-19 associated hypoxaemia
    Thomas Voshaar, Patrick Stais, Dieter Köhler, Dominic Dellweg
    ERJ Open Res 7: 00134-2021; DOI: 10.1183/23120541.00134-2021 Published 6 April 2021
  • Open Access
    Is it feasible to collect exhaled breath condensate in COVID-19 patients undergoing noninvasive ventilatory support?
    Paola Pierucci, Rosanna Vaschetto, Giovanna E. Carpagnano
    ERJ Open Res 7: 00071-2021; DOI: 10.1183/23120541.00071-2021 Published 24 May 2021
  • Open Access
    Conservative management of COVID-19 associated hypoxaemia
    Alexander Supady, Philipp M. Lepper, Hendrik Bracht, Onnen Moerer, Ralf M. Muellenbach, Guido Michels, Mascha O. Fiedler, Armin Kalenka, Matthias Kochanek, Haitham Mutlak, Guy Danziger, Sebastian Muenz, Dirk Lunz, Sabrina Hoersch, Dawid Staudacher, Tobias Wengenmayer, Viviane Zotzmann
    ERJ Open Res 7: 00204-2021; DOI: 10.1183/23120541.00204-2021 Published 21 June 2021
  • Open Access
    Conservative management of COVID-19 associated hypoxaemia
    Thomas Voshaar, Patrick Stais, Dieter Köhler, Dominic Dellweg
    ERJ Open Res 7: 00292-2021; DOI: 10.1183/23120541.00292-2021 Published 21 June 2021

Author correction

  • Open Access
    “Expression of endocannabinoid system components in human airway epithelial cells: impact of sex and chronic respiratory disease status”. Matthew F. Fantauzzi, Jennifer A. Aguiar, Benjamin J-M. Tremblay, Michael J. Mansfield, Toyoshi Yanagihara, Abiram Chandiramohan, Spencer Revill, Min Hyung Ryu, Chris Carlsten, Kjetil Ask, Martin Stämpfli, Andrew C. Doxey and Jeremy A. Hirota. ERJ Open Res 2020; 6: 00128-2020.
    ERJ Open Res 7: 50128-2020; DOI: 10.1183/23120541.50128-2020 Published 31 May 2021

Erratum

  • Open Access
    “Lung volume reduction in emphysema: a pragmatic prospective cohort study”. Christophe Dooms, Astrid Blondeel, Laurens J. Ceulemans, Johan Coolen, Stephanie Everaerts, Heleen Demeyer, Thierry Troosters Geert Verleden, Dirk Van Raemdonck and Wim Janssens. ERJ Open Res 2021; 7: 00877-2020
    ERJ Open Res 7: 50877-2020; DOI: 10.1183/23120541.50877-2020 Published 21 June 2021
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ERJ Open Research: 7 (2)
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  • Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome?
  • IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette
  • A potential harmful effect of dexamethasone in non-severe COVID-19: results from the COPPER-pilot study
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