Figures
- FIGURE 1
Presence of Cutibacterium acnes in tissue and granulomas of patients with hypersensitivity pneumonitis (HP) and (eosinophilic) granulomatosis with polyangiitis ((E)GPA). a) Characteristics of all included patients and percentage of patients with presence of C. acnes in tissue or in tissue and granulomas. The sarcoidosis group was previously described [6]. No significant difference was observed between the three groups regarding C. acnes in tissue or C. acnes in granulomas (p=0.210 and p=0.460, respectively). Data are presented as n (%) unless otherwise stated. b) Haematoxylin and eosin stain (HE) stain of lung tissue from an HP patient. The black arrows show granulomas. Scale bar=100 μm. c) Positive PAB immunohistochemistry (red) in the granulomas corresponding to (b). Scale bar=100 μm. d) Higher-magnification image corresponding to the square in picture (c). Scale bar=50 μm. e) Area of positive PAB immunohistochemistry outside granulomas. Scale bar=50 μm. f) HE stain of lung tissue from an EGPA patient, with an immature granuloma indicated by the circle. Scale bar=50 μm. g) Positive PAB immunohistochemistry in the granuloma corresponding to (f). Scale bar=50 μm. h) Higher-magnification image corresponding to the square in (g). Scale bar=50 μm. i) Area of positive PAB immunohistochemistry outside granulomas. Scale bar=50 μm. ns: nonsignificant; NA: not applicable.
