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Prevalence of asymptomatic bronchiectasis and associations among the health screening population in South Korea

Soo Han Kim, Young Ju Jung, Myung-Su Ko, Sei Won Lee, Jae Seung Lee, Yeon-Mok Oh
ERJ Open Research 2021 7: 00188-2021; DOI: 10.1183/23120541.00188-2021
Soo Han Kim
1Dept of Internal Medicine, Biomedical Research Institute, Pusan National University Hospital, Seo-gu, Busan, Korea
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Young Ju Jung
2Dept of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Centre, Songpa-gu, Seoul, Korea
3Health Screening and Promotion Centre, Asan Medical Centre, Songpa-gu, Seoul, Korea
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Myung-Su Ko
3Health Screening and Promotion Centre, Asan Medical Centre, Songpa-gu, Seoul, Korea
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Sei Won Lee
2Dept of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Centre, Songpa-gu, Seoul, Korea
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Jae Seung Lee
2Dept of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Centre, Songpa-gu, Seoul, Korea
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Yeon-Mok Oh
2Dept of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Centre, Songpa-gu, Seoul, Korea
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  • For correspondence: ymoh55@amc.seoul.kr
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  • FIGURE 1
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    FIGURE 1

    Flow chart of the study population. CT: computed tomography.

  • FIGURE 2
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    FIGURE 2

    Frequency of comorbidities among non-bronchiectasis, asymptomatic bronchiectasis and symptomatic bronchiectasis. *p<0.05, **p<0.01. PVD: peripheral vascular disease; CVD: cerebrovascular disease; GERD: gastro-oesophageal reflux disease; IBD: inflammatory bowel disease.

  • FIGURE 3
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    FIGURE 3

    Prevalence of bronchiectasis based on age group and sex in South Korea during 2016–2017.

  • FIGURE 4
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    FIGURE 4

    Factors related to asymptomatic bronchiectasis. BMI: body mass index; CRP: C-reactive protein; CVD: cerebrovascular disease; FEV1: forced expiratory volume in 1 s; GERD: gastro-oesophageal reflux disease; Hx: history; IBD: inflammatory bowel disease; PVD: peripheral vascular disease.

Tables

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  • TABLE 1

    Baseline characteristics of non-bronchiectasis, asymptomatic bronchiectasis and symptomatic bronchiectasis

    Non-bronchiectasis (A)Asymptomatic bronchiectasis (B)Symptomatic bronchiectasis (C)p-value
    A versus B versus CA versus BB versus CA versus C
    Subjects n16 143566439
    Female sex5555 (34.4)221 (39.0)199 (45.3)<0.0010.0230.045<0.001
    Age years58.19±8.5864.24±7.4062.64±7.71<0.001<0.0010.402<0.001
    BMI (n=16 136/566/439)0.5800.6050.2490.410
     Underweight (BMI <18.5 kg·m−2)462 (2.9)14 (2.5)16 (3.6)
     Normal weight (BMI ≥18.5 and  <25 kg·m−2)10 926 (67.7)394 (69.6)286 (65.1)
     Overweight or obesity (BMI  ≥25 kg·m−2)4748 (29.4)158 (27.9)137 (31.2)
    Smoking history (n=16 090/563/437)<0.001<0.0010.3220.002
    Never smoker7523 (46.8)301 (53.5)242 (55.4)
    Former smoker5371 (33.4)184 (32.7)125 (28.6)
    Current smoker3196 (19.9)78 (13.9)70 (16.0)
    PFT: FEV1 % predicted (n=15 747/553/430)92.06±11.1890.42±12.0785.63±14.69<0.0010.002<0.0010.001
    Laboratory test
     Haemoglobin g·dL−1 (n=16 140/  566/439)14.61±1.4114.44±1.4214.38±1.44<0.0010.0060.537<0.001
     CRP mg·dL−1 (n=14 618/517/403)0.11±0.160.11±0.150.16±0.25<0.0010.363<0.001<0.001

    Continuous variables are presented as mean±sd; categorical variables are presented as number (%). BMI: body mass index; CRP: C-reactive protein; FEV1: forced expiratory volume in 1 s; PFT: pulmonary function test.

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      Supplementary material 00188-2021.supplement

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    Prevalence of asymptomatic bronchiectasis and associations among the health screening population in South Korea
    Soo Han Kim, Young Ju Jung, Myung-Su Ko, Sei Won Lee, Jae Seung Lee, Yeon-Mok Oh
    ERJ Open Research Jul 2021, 7 (3) 00188-2021; DOI: 10.1183/23120541.00188-2021

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    Prevalence of asymptomatic bronchiectasis and associations among the health screening population in South Korea
    Soo Han Kim, Young Ju Jung, Myung-Su Ko, Sei Won Lee, Jae Seung Lee, Yeon-Mok Oh
    ERJ Open Research Jul 2021, 7 (3) 00188-2021; DOI: 10.1183/23120541.00188-2021
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