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Adaptive study design to assess effect of TRPV4 inhibition in patients with chronic cough

Valerie J. Ludbrook, Kate E. Hanrott, James L. Kreindler, Joanna E. Marks-Konczalik, Nick P. Bird, Debbie A. Hewens, Misba Beerahee, David J. Behm, Alyn Morice, Lorcan McGarvey, Sean M. Parker, Surinder S. Birring, Jaclyn Smith
ERJ Open Research 2021 7: 00269-2021; DOI: 10.1183/23120541.00269-2021
Valerie J. Ludbrook
1GlaxoSmithKline, Stevenage, UK
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  • For correspondence: Valerie.J.Ludbrook@GSK.com
Kate E. Hanrott
1GlaxoSmithKline, Stevenage, UK
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James L. Kreindler
2GlaxoSmithKline, Upper Providence, USA
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Joanna E. Marks-Konczalik
1GlaxoSmithKline, Stevenage, UK
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Nick P. Bird
1GlaxoSmithKline, Stevenage, UK
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Debbie A. Hewens
1GlaxoSmithKline, Stevenage, UK
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Misba Beerahee
1GlaxoSmithKline, Stevenage, UK
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David J. Behm
2GlaxoSmithKline, Upper Providence, USA
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Alyn Morice
3Hull York Medical School, Cottingham, UK
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  • ORCID record for Alyn Morice
Lorcan McGarvey
4Queens University, Belfast, UK
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Sean M. Parker
5North Tyneside General Hospital, North Shields, UK
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Surinder S. Birring
6Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK
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Jaclyn Smith
7Division of Infection Immunity and Respiratory Medicine, University of Manchester and Manchester University NHS Foundation Trust, Manchester, UK
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Article Information

vol. 7 no. 3
DOI 
https://doi.org/10.1183/23120541.00269-2021

Published By 
European Respiratory Society
Online ISSN 
2312-0541
History 
  • Received April 19, 2021
  • Accepted June 4, 2021
  • Published online August 2, 2021.

Article Versions

  • previous version (June 17, 2021 - 07:22).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright ©The authors 2021 This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org

Author Information

  1. Valerie J. Ludbrook1⇑,
  2. Kate E. Hanrott1,
  3. James L. Kreindler2,
  4. Joanna E. Marks-Konczalik1†,
  5. Nick P. Bird1,
  6. Debbie A. Hewens1,
  7. Misba Beerahee1,
  8. David J. Behm2,
  9. Alyn Morice3,
  10. Lorcan McGarvey4,
  11. Sean M. Parker5,
  12. Surinder S. Birring6 and
  13. Jaclyn Smith7
  1. 1GlaxoSmithKline, Stevenage, UK
  2. 2GlaxoSmithKline, Upper Providence, USA
  3. 3Hull York Medical School, Cottingham, UK
  4. 4Queens University, Belfast, UK
  5. 5North Tyneside General Hospital, North Shields, UK
  6. 6Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK
  7. 7Division of Infection Immunity and Respiratory Medicine, University of Manchester and Manchester University NHS Foundation Trust, Manchester, UK
  1. Corresponding author: Valerie Ludbrook (Valerie.J.Ludbrook{at}GSK.com)
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Funding

  • US Federal Government funds from the Department of Health and Human Services (Office of the Assistant Secretary for Preparedness and Response; Biomedical Advanced Research and Development Authority)

    HHSO100201700009C
  • GlaxoSmithKline

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Vol 7 Issue 3 Table of Contents
ERJ Open Research: 7 (3)
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Adaptive study design to assess effect of TRPV4 inhibition in patients with chronic cough
Valerie J. Ludbrook, Kate E. Hanrott, James L. Kreindler, Joanna E. Marks-Konczalik, Nick P. Bird, Debbie A. Hewens, Misba Beerahee, David J. Behm, Alyn Morice, Lorcan McGarvey, Sean M. Parker, Surinder S. Birring, Jaclyn Smith
ERJ Open Research Jul 2021, 7 (3) 00269-2021; DOI: 10.1183/23120541.00269-2021

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Adaptive study design to assess effect of TRPV4 inhibition in patients with chronic cough
Valerie J. Ludbrook, Kate E. Hanrott, James L. Kreindler, Joanna E. Marks-Konczalik, Nick P. Bird, Debbie A. Hewens, Misba Beerahee, David J. Behm, Alyn Morice, Lorcan McGarvey, Sean M. Parker, Surinder S. Birring, Jaclyn Smith
ERJ Open Research Jul 2021, 7 (3) 00269-2021; DOI: 10.1183/23120541.00269-2021
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