Abstract
Background: Obstructive Sleep Apnea (OSA) has an increasing prevalence and is associated with changes leading to cardiac remodeling.
Objective: To correlate the severity of OSA with left and right 2d-echocardiographic changes.
Methods: This is a retrospective study which included patients somnographically diagnosed with OSA with sleep polysomnogram and 2d-echocardiogram done in the institution. Parameters such as AHI, ejection fraction (EF), left ventricular mass index (LVMi), relative wall thickness (RWT), ratio of mitral inflow velocity and lateral annulus velocity (E/e’).and Tricuspid Annulus Peak Systolic Excursion (TAPSE) were correlated using Analysis of Variance and Fisher Exact Test.
Results: 52 patients with OSA were included with a mean age of 49.2 + 11.7 years and mostly males (84.62%). The study population had EF of 62.6 + 3.8% for mild, 62.3 + 3.8% for moderate, and 64.1 + 3.4% for severe OSA (p= 0.2781), LVMi were 96.7 + 23.1 g/m2 for mild, 100.4 + 22.7 g/m2 for moderate and 95.6 + 23.6 g/m2 for severe OSA (p= 0.8680), RWT were 0.424 + 0.05 cm for mild, 0.451 + 0.4 cm for moderate and 0.433 + 0.07 cm for severe OSA (p= 0.6352), E/e’ were 8.4 + 4.4 cm/s for mild, 5.9 + 2.3 cm/s for moderate and 6.7 + 2.7 cm/s for severe OSA (p= 0.1533) and TAPSE were 20.0 + 2.7 mm for mild, 20.4 + 1.9 mm for moderate and 21.3 + 2.9 mm for severe OSA (p= 0.3577).
Conclusion: Patients with OSA regardless of severity have left ventricular concentric remodeling, adequate left ventricular function, preserved right ventricular systolic function and normal estimated pulmonary capillary wedge pressure.
Footnotes
Cite this article as ERJ Open Research 2021; 7: Suppl. 7, 2.
This is an ERS Lung Science Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021
