Abstract
Objective: To investigate the impact of different EPAP levels in NIV on elderly OSAHS patients.
Methods: A comparative study, all patients were diagnosed with OSAHS, a total of 48 elderly patients were included (age: (71±8.4 yrs,BMI:28.3±7.4kg/m2). Depending on the level of EPAP , all subjects were randomly divided (1:1:1) into three groups: Narrow scale-EPAP group (EPAP min=8cmH2O, EPAPmax=10cmH2O), Wide scale-EPAP group (EPAP min=4cmH2O,EPAPmax=16 cmH2O) and fixed EPAP group (EPAP=8cmH2O), all patients underwent NIV, AVAPS-AE mode in both Narrow scale-EPAP group and Wide scale- EPAP group; AVAPS mode in the fixed EPAP group.
Results: There were significant differences in leakage among the “Fixed-scale EPAP” and “Wide-scale EPAP group” (18.2±4.4L/min VS.15.4±2.5 L/min, p=0.037), lower occurrence of intra-abdominal hypertension in Wide-scale EPAP group than in Fixed-scale EPAP group(p<0.05).There were no differences in lowest oxygen saturation(LSaO2) and improvement of Epworth Sleepiness Scale(ESS) and AHI among three groups. Compared with wide scale-EPAP group, higher occurrence of patient-ventilator asynchronization in fixed EPAP group: but there was no statistical differences(43.8% vs. 25.0%,X2=1.247,p=0.264).
Conclusions: For elderly OSAHS patients, a varying range of EPAP maybe more likely to improve their comfort during NIV ,rather than a fixed EPAP level. But, there were no significant differences in changes in improvement of LSaO2 ,ESS and AHI, our results need further study.
Footnotes
Cite this article as ERJ Open Research 2021; 7: Suppl. 7, 65.
This is an ERS Lung Science Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2021