Skip to main content

Main menu

  • Home
  • Current issue
  • Early View
  • Archive
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • COVID-19 submission information
    • Institutional open access agreements
    • Peer reviewer login
  • Alerts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • Early View
  • Archive
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • COVID-19 submission information
    • Institutional open access agreements
    • Peer reviewer login
  • Alerts
  • Subscriptions

Outcomes and survival following lung transplantation in non-cystic fibrosis bronchiectasis

Frederick Jung, Leonard Riley, Jorge Lascano
ERJ Open Research 2022 8: 00607-2021; DOI: 10.1183/23120541.00607-2021
Frederick Jung
Dept of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida College of Medicine, Gainesville, FL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Frederick Jung
  • For correspondence: Frederick.Jung@medicine.ufl.edu
Leonard Riley
Dept of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida College of Medicine, Gainesville, FL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Leonard Riley
Jorge Lascano
Dept of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida College of Medicine, Gainesville, FL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jorge Lascano
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Figures

  • Tables
  • FIGURE 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 1

    Kaplan–Meier survival curve of patients transplanted for non-cystic fibrosis bronchiectasis (solid red line) compared to lung transplant recipients for all other diseases combined (solid blue line) with 95% confidence intervals (dashed lines).

Tables

  • Figures
  • TABLE 1

    Baseline characteristics of NCFB listed and transplant recipients

    VariableListed patientsTransplanted patients
    Age years47 (37–55)47 (37–56)
    Sex, female431 (60)221 (54)
    BMI kg·m−221.8 (18.9–25.2)21.8 (18.8–25.1)
    FEV1 % predicted24 (19–31)24 (19–31)
    FVC % predicted41 (33–51)41 (33–51)
    Lung allocation score34.9 (32.8–37.6)36.9 (34.3–43.8)
    Waiting-list time days337 (110–808)254 (83–568)
    Waiting-list time post-LAS days (n=202)170 (54–450)119 (36–301)

    Data expressed as median (interquartile range) or n (%). NCFB: non-cystic fibrosis bronchiectasis; BMI: body mass index; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; LAS: lung allocation score.

    • TABLE 2

      Overall number depicting the type of transplant and the outcomes following lung transplantation in the cohort of 407 non-cystic fibrosis bronchiectasis patients

      Outcomen (%)
      Alive114 (28)
      Dead263 (65)
      Missing data16 (4)
      Retransplanted14 (3)
    • TABLE 3

      Summary of survival for lung transplant recipients in the post-LAS period for NCFB compared to an age- and sex-matched cohort

      GroupMedian (IQR) years1-year survival %5-year survival %10-year survival %
      NCFB6.0 (2.3–11.9)875316
      Matched cohort5.5 (2.3–13.2)845528

      LAS: lung allocation score; NCFB: non-cystic fibrosis bronchiectasis; IQR: interquartile range.

      • TABLE 4

        Aetiology of death for non-cystic fibrosis bronchiectasis lung transplantation recipients

        Aetiology of deathn (%)
        Graft failure64 (24)
        Infection59 (23)
        Respiratory failure49 (19)
        Unknown39 (15)
        Multiple organ failure14 (5)
        Cardiovascular12 (5)
        Malignancy11 (4)
        Cerebrovascular6 (2)
        Haemorrhage4 (2)
        Renal failure4 (2)
        Suicide1 (0.4)
      PreviousNext
      Back to top
      Vol 8 Issue 1 Table of Contents
      ERJ Open Research: 8 (1)
      • Table of Contents
      • Index by author
      Email

      Thank you for your interest in spreading the word on European Respiratory Society .

      NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

      Enter multiple addresses on separate lines or separate them with commas.
      Outcomes and survival following lung transplantation in non-cystic fibrosis bronchiectasis
      (Your Name) has sent you a message from European Respiratory Society
      (Your Name) thought you would like to see the European Respiratory Society web site.
      CAPTCHA
      This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
      Print
      Citation Tools
      Outcomes and survival following lung transplantation in non-cystic fibrosis bronchiectasis
      Frederick Jung, Leonard Riley, Jorge Lascano
      ERJ Open Research Jan 2022, 8 (1) 00607-2021; DOI: 10.1183/23120541.00607-2021

      Citation Manager Formats

      • BibTeX
      • Bookends
      • EasyBib
      • EndNote (tagged)
      • EndNote 8 (xml)
      • Medlars
      • Mendeley
      • Papers
      • RefWorks Tagged
      • Ref Manager
      • RIS
      • Zotero
      Share
      Outcomes and survival following lung transplantation in non-cystic fibrosis bronchiectasis
      Frederick Jung, Leonard Riley, Jorge Lascano
      ERJ Open Research Jan 2022, 8 (1) 00607-2021; DOI: 10.1183/23120541.00607-2021
      del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo
      Full Text (PDF)

      Jump To

      • Article
        • Abstract
        • Abstract
        • Introduction
        • Materials and methods
        • Results
        • Discussion
        • Footnotes
        • References
      • Figures & Data
      • Info & Metrics
      • PDF

      Subjects

      • CF and non-CF bronchiectasis
      • Tweet Widget
      • Facebook Like
      • Google Plus One

      More in this TOC Section

      Original research articles

      • Functional assay in CF organoids allows drug repurposing
      • Bacterial DNA amplifies neutrophilic inflammation in IL-17-exposed airways
      • PERSPIRE: a cohort study
      Show more Original research articles

      Bronchiectasis

      • Bronchiectasis, immunodeficiency and treatable traits
      • Bronchiectasis therapy comparative safety
      Show more Bronchiectasis

      Related Articles

      Navigate

      • Home
      • Current issue
      • Archive

      About ERJ Open Research

      • Editorial board
      • Journal information
      • Press
      • Permissions and reprints
      • Advertising

      The European Respiratory Society

      • Society home
      • myERS
      • Privacy policy
      • Accessibility

      ERS publications

      • European Respiratory Journal
      • ERJ Open Research
      • European Respiratory Review
      • Breathe
      • ERS books online
      • ERS Bookshop

      Help

      • Feedback

      For authors

      • Instructions for authors
      • Publication ethics and malpractice
      • Submit a manuscript

      For readers

      • Alerts
      • Subjects
      • RSS

      Subscriptions

      • Accessing the ERS publications

      Contact us

      European Respiratory Society
      442 Glossop Road
      Sheffield S10 2PX
      United Kingdom
      Tel: +44 114 2672860
      Email: journals@ersnet.org

      ISSN

      Online ISSN: 2312-0541

      Copyright © 2023 by the European Respiratory Society