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Chronic effects of occupational exposure to mineral fibres and recurrent chest infections in insulators

Subhabrata Moitra, Ali Farshchi Tabrizi, Linda Henderson, Fadi Khadour, Mohamed Osman, Lyle Melenka, Paige Lacy
ERJ Open Research 2022 8: 00095-2022; DOI: 10.1183/23120541.00095-2022
Subhabrata Moitra
1Alberta Respiratory Centre, Division of Pulmonary Medicine, Dept of Medicine, University of Alberta, Edmonton, AB, Canada
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Ali Farshchi Tabrizi
1Alberta Respiratory Centre, Division of Pulmonary Medicine, Dept of Medicine, University of Alberta, Edmonton, AB, Canada
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Linda Henderson
2Synergy Respiratory and Cardiac Care, Sherwood Park, AB, Canada
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Fadi Khadour
2Synergy Respiratory and Cardiac Care, Sherwood Park, AB, Canada
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Mohamed Osman
3Division of Rheumatology, Dept of Medicine, University of Alberta, Edmonton, AB, Canada
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Lyle Melenka
2Synergy Respiratory and Cardiac Care, Sherwood Park, AB, Canada
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Paige Lacy
1Alberta Respiratory Centre, Division of Pulmonary Medicine, Dept of Medicine, University of Alberta, Edmonton, AB, Canada
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  • For correspondence: placy@ualberta.ca
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Tables

  • TABLE 1

    Demographic, exposure and clinical characteristics of study participants

    Participants272
    Demographics
     Age, years#46.9±13.6
     Male248 (91)
     BMI, kg·m−2#29.6±6.0
     Ever smokers173 (64)
     Smoking pack-years3 (0–16.4)
     Caucasian ethnicity219 (81)
     Educational qualifications
      Grade school8 (3)
      High school36 (13)
      Trade school128 (47)
      College/university100 (37)
     Marital status
      Single/unmarried82 (30)
      Married/with a partner172 (63)
      Divorced/separated/widowed18 (7)
    Exposure history
     Childhood smoke exposure182 (67)
     Parental lung condition74 (27)
     Exposure to mineral fibres#259 (95)
     Use of PPE for mineral fibres#161 (59)
    Clinical profile
     Episodes of chest infection in the past 3 years¶,+2 (1–2)
    White blood cell profileBaselineFollow-up+
     Neutrophil %58±1059±10
     Eosinophil %3±23±2
     Lymphocyte %30±830±9
     Monocyte %8±28±2
     Lymphocyte/monocyte ratio§3.84±1.313.76±1.45
     Neutrophil/lymphocyte ratio§2.26±1.452.31±1.19

    Data are presented as mean±sd or median (interquartile range) for numerical variables, and n (%) for categorical variables. BMI: body mass index; PPE: personal protective equipment. #: data taken at the baseline visit; ¶: data taken at the follow-up visit; +: median interval between baseline and follow-up visit was 3.8 years; §: ratio of absolute count.

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    Chronic effects of occupational exposure to mineral fibres and recurrent chest infections in insulators
    Subhabrata Moitra, Ali Farshchi Tabrizi, Linda Henderson, Fadi Khadour, Mohamed Osman, Lyle Melenka, Paige Lacy
    ERJ Open Research Apr 2022, 8 (2) 00095-2022; DOI: 10.1183/23120541.00095-2022

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    Chronic effects of occupational exposure to mineral fibres and recurrent chest infections in insulators
    Subhabrata Moitra, Ali Farshchi Tabrizi, Linda Henderson, Fadi Khadour, Mohamed Osman, Lyle Melenka, Paige Lacy
    ERJ Open Research Apr 2022, 8 (2) 00095-2022; DOI: 10.1183/23120541.00095-2022
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