Dysglycaemia among tuberculosis patients without known diabetes in a low-endemic setting

Anja Jørgensen; Hans Johan Niklas Lorentsson; Franziska Grundtvig Huber; Sidse Graff Jensen; Karen Bjorn-Mortensen; Pernille Ravn

doi:10.1183/23120541.00629-2021

Tables

TABLE 1

Univariate and multivariate regression analyses for risk factors of having HbA1c ≥39 mmol·mol⁻¹ at the time of tuberculosis (TB) diagnosis

Risk factor	Crude analysis		Multivariate analysis^#
Risk factor	OR (95% CI)	p-value	OR (95% CI)	p-value
Age
≤40 years	1 (ref.)		1 (ref.)
>40 years	6.3 (2.2–22.8)	0.002	5.6 (1.9–20.9)	0.004
Sex
Female	1 (ref.)		1 (ref.)
Male	5.4 (2.0–17.2)	0.002	4.6 (1.7–14.9)	0.006
Substance use
No history of excessive alcohol intake	1 (ref.)		1 (ref.)
History of excessive alcohol intake	2.4 (1.0–5.6)	0.044	2.0 (1.0–5.1)	0.138
No history of smoking	1 (ref.)		1 (ref.)
Previous or current smoker	1.7 (0.7–4.4)	0.271	0.6 (0.2–1.9)	0.396
No history of drug use	1 (ref.)		1 (ref.)
History of drug use	1.0 (0.4–2.4)	0.994	1.1 (0.4–3.1)	0.862
Region of origin
Denmark	1 (ref.)		1 (ref.)
Greenland	1.9 (0.6–5.6)	0.243	3.6 (1.0–14.6)	0.056
Immigrant^¶	1.3 (0.6–3.2)	0.495	5.9 (1.7–24.2)	0.009
Disease presentation
Pulmonary TB	1 (ref.)		1 (ref.)
Extra-pulmonary TB	0.2 (0.0–1.1)	0.123	0.3 (0.0–1.7)	0.234
Disseminated TB⁺	7.5 (1.6–54.0)	0.017	10.6 (1.8–91.5)	0.013
No cavitations^§	1 (ref.)		1 (ref.)
Cavitations^§	4.8 (1.8–13.3)	0.002	5.3 (1.8–17.2)	0.003

^#: adjusted for age and sex, not including the measured risk factor; ^¶: all patients not born in Denmark or Greenland; ⁺: more than one TB location, including military TB; ^§: in patients with pulmonary TB.