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Bilateral endobronchial valves treatment for severe emphysema

Nicolas Guibert, Romane Fumat, Marion Dupuis, Matthieu Dusselier, Florent Favard, Valentin Heluain, Siham Mallah, Romain Barthes, Yannick Simonneau, Thomas Egenod
ERJ Open Research 2022 8: 00672-2021; DOI: 10.1183/23120541.00672-2021
Nicolas Guibert
1Pulmonology Dept, Larrey University Hospital, Toulouse, France
2Paul Sabatier Toulouse University III, Toulouse, France
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  • For correspondence: guibert.n@chu-toulouse.fr
Romane Fumat
1Pulmonology Dept, Larrey University Hospital, Toulouse, France
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Marion Dupuis
1Pulmonology Dept, Larrey University Hospital, Toulouse, France
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Matthieu Dusselier
3Pulmonology Dept, Dupuytren University Hospital, Limoges, France
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Florent Favard
3Pulmonology Dept, Dupuytren University Hospital, Limoges, France
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Valentin Heluain
1Pulmonology Dept, Larrey University Hospital, Toulouse, France
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Siham Mallah
1Pulmonology Dept, Larrey University Hospital, Toulouse, France
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Romain Barthes
1Pulmonology Dept, Larrey University Hospital, Toulouse, France
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Yannick Simonneau
3Pulmonology Dept, Dupuytren University Hospital, Limoges, France
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Thomas Egenod
3Pulmonology Dept, Dupuytren University Hospital, Limoges, France
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    FIGURE 1

    a) Main outcomes after each procedure and combined outcomes. b) Computed tomography scan and c) perfusion tomoscintigraphy showing the example of a patient with an extremely heterogeneous emphysema who experienced dramatic improvements after both interventions: forced expiratory volume in 1 s (FEV1) increase by 73% after a first right lower lobe EBV treatment (460 mL to 800 mL) and 74% more after a subsequent left lower lobe treatment (800 mL to 1380 mL), after an overall 2950 mL residual volume (RV) decrease (7840 to 4890 mL). d) Changes in the main parameters: RV, FEV1, 6-min walking distance (6MWD) and BODE (body mass index, obstruction (FEV1), dyspnoea (modified Medical Research Council dyspnoea score (mMRC)), exercise capacity (6MWD)) score (median) after the first procedure (T1) and after contralateral treatment (T2). TLVR: target lung volume reduction; NA: not applicable.

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Vol 8 Issue 2 Table of Contents
ERJ Open Research: 8 (2)
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Bilateral endobronchial valves treatment for severe emphysema
Nicolas Guibert, Romane Fumat, Marion Dupuis, Matthieu Dusselier, Florent Favard, Valentin Heluain, Siham Mallah, Romain Barthes, Yannick Simonneau, Thomas Egenod
ERJ Open Research Apr 2022, 8 (2) 00672-2021; DOI: 10.1183/23120541.00672-2021

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Bilateral endobronchial valves treatment for severe emphysema
Nicolas Guibert, Romane Fumat, Marion Dupuis, Matthieu Dusselier, Florent Favard, Valentin Heluain, Siham Mallah, Romain Barthes, Yannick Simonneau, Thomas Egenod
ERJ Open Research Apr 2022, 8 (2) 00672-2021; DOI: 10.1183/23120541.00672-2021
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