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Prevalence and burden of chronic cough in China: a national cross-sectional study

Kewu Huang, Xiaoying Gu, Ting Yang, Jianying Xu, Lan Yang, Jianping Zhao, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen, Yahong Chen, Tieying Sun, Guangliang Shan, Yingxiang Lin, Sinan Wu, Ruiying Wang, Zhihong Shi, Yongjian Xu, Xianwei Ye, Yuanlin Song, Qiuyue Wang, Yumin Zhou, Wen Li, Liren Ding, Chun Wan, Wanzhen Yao, Yanfei Guo, Fei Xiao, Yong Lu, Xiaoxia Peng, Dan Xiao, Xiaoning Bu, Hong Zhang, Xiaolei Zhang, Li An, Shu Zhang, Zhixin Cao, Qingyuan Zhan, Yuanhua Yang, Lirong Liang, Huaping Dai, Bin Cao, Jiang He, Kian Fan Chung, Chen Wang for the China Pulmonary Health (CPH) Study Group
ERJ Open Research 2022 8: 00075-2022; DOI: 10.1183/23120541.00075-2022
Kewu Huang
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Xiaoying Gu
3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
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Ting Yang
3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
6Dept of Respiratory Medicine, Capital Medical University, Beijing, China
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Jianying Xu
7Dept of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital, Taiyuan, China
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Lan Yang
8Dept of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
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Jianping Zhao
9Dept of Pulmonary and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Xiangyan Zhang
10Dept of Pulmonary and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China
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Chunxue Bai
11Dept of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China
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  • ORCID record for Chunxue Bai
Jian Kang
12Dept of Pulmonary and Critical Care Medicine, The First Hospital of China Medical University, Shenyang, China
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Pixin Ran
13State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
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Huahao Shen
14Dept of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
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Fuqiang Wen
15State Key Laboratory of Biotherapy of China and Dept of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China
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Yahong Chen
16Dept of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China
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Tieying Sun
17Dept of Respiratory and Critical Care Medicine, Beijing Hospital, Beijing, China
18National Center of Gerontology, Beijing Hospital, Beijing, China
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Guangliang Shan
19Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences; School of Basic Medicine, Peking Union Medical College, Beijing, China
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Yingxiang Lin
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Sinan Wu
3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
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Ruiying Wang
7Dept of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital, Taiyuan, China
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Zhihong Shi
8Dept of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
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Yongjian Xu
9Dept of Pulmonary and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Xianwei Ye
10Dept of Pulmonary and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China
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Yuanlin Song
11Dept of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China
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Qiuyue Wang
12Dept of Pulmonary and Critical Care Medicine, The First Hospital of China Medical University, Shenyang, China
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Yumin Zhou
13State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
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Wen Li
14Dept of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
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Liren Ding
14Dept of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
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Chun Wan
15State Key Laboratory of Biotherapy of China and Dept of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China
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Wanzhen Yao
16Dept of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China
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Yanfei Guo
17Dept of Respiratory and Critical Care Medicine, Beijing Hospital, Beijing, China
18National Center of Gerontology, Beijing Hospital, Beijing, China
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Fei Xiao
18National Center of Gerontology, Beijing Hospital, Beijing, China
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Yong Lu
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Xiaoxia Peng
20Center for Clinical Epidemiology and Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
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Dan Xiao
3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
21WHO Collaborating Center for Tobacco Cessation and Respiratory Diseases Prevention, Beijing, China
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Xiaoning Bu
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Hong Zhang
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Xiaolei Zhang
3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
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Li An
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Shu Zhang
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Zhixin Cao
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Qingyuan Zhan
3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
6Dept of Respiratory Medicine, Capital Medical University, Beijing, China
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Yuanhua Yang
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Lirong Liang
1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Beijing Institute of Respiratory Medicine, Beijing, China
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Huaping Dai
3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
6Dept of Respiratory Medicine, Capital Medical University, Beijing, China
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Bin Cao
3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
6Dept of Respiratory Medicine, Capital Medical University, Beijing, China
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Jiang He
22Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
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Kian Fan Chung
23National Heart & Lung Institute, Imperial College London, and Royal Brompton & Harefield NHS Trust, London, UK
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Chen Wang
3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
6Dept of Respiratory Medicine, Capital Medical University, Beijing, China
21WHO Collaborating Center for Tobacco Cessation and Respiratory Diseases Prevention, Beijing, China
24Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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  • For correspondence: wangchen@pumc.edu.cn
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Article Information

vol. 8 no. 3
DOI 
https://doi.org/10.1183/23120541.00075-2022

Published By 
European Respiratory Society
Online ISSN 
2312-0541
History 
  • Received February 9, 2022
  • Accepted March 16, 2022
  • Published online July 25, 2022.

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  • previous version (April 21, 2022 - 08:27).
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Copyright ©The authors 2022 This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org

Author Information

  1. Kewu Huang1,2,
  2. Xiaoying Gu3,4,5,
  3. Ting Yang3,4,5,6,
  4. Jianying Xu7,
  5. Lan Yang8,
  6. Jianping Zhao9,
  7. Xiangyan Zhang10,
  8. Chunxue Bai11,
  9. Jian Kang12,
  10. Pixin Ran13,
  11. Huahao Shen14,
  12. Fuqiang Wen15,
  13. Yahong Chen16,
  14. Tieying Sun17,18,
  15. Guangliang Shan19,
  16. Yingxiang Lin1,2,
  17. Sinan Wu3,4,5,
  18. Ruiying Wang7,
  19. Zhihong Shi8,
  20. Yongjian Xu9,
  21. Xianwei Ye10,
  22. Yuanlin Song11,
  23. Qiuyue Wang12,
  24. Yumin Zhou13,
  25. Wen Li14,
  26. Liren Ding14,
  27. Chun Wan15,
  28. Wanzhen Yao16,
  29. Yanfei Guo17,18,
  30. Fei Xiao18,
  31. Yong Lu1,2,
  32. Xiaoxia Peng20,
  33. Dan Xiao3,4,5,21,
  34. Xiaoning Bu1,2,
  35. Hong Zhang1,2,
  36. Xiaolei Zhang3,4,5,
  37. Li An1,2,
  38. Shu Zhang1,2,
  39. Zhixin Cao1,2,
  40. Qingyuan Zhan3,4,5,6,
  41. Yuanhua Yang1,2,
  42. Lirong Liang1,2,
  43. Huaping Dai3,4,5,6,
  44. Bin Cao3,4,5,6,
  45. Jiang He22,
  46. Kian Fan Chung23 and
  47. Chen Wang3,4,5,6,21,24⇑
  48. for the China Pulmonary Health (CPH) Study Group
  1. 1Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Dept of Pulmonary and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
  2. 2Beijing Institute of Respiratory Medicine, Beijing, China
  3. 3National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Beijing, China
  4. 4Dept of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China
  5. 5Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, China
  6. 6Dept of Respiratory Medicine, Capital Medical University, Beijing, China
  7. 7Dept of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital, Taiyuan, China
  8. 8Dept of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
  9. 9Dept of Pulmonary and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
  10. 10Dept of Pulmonary and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China
  11. 11Dept of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China
  12. 12Dept of Pulmonary and Critical Care Medicine, The First Hospital of China Medical University, Shenyang, China
  13. 13State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
  14. 14Dept of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
  15. 15State Key Laboratory of Biotherapy of China and Dept of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China
  16. 16Dept of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China
  17. 17Dept of Respiratory and Critical Care Medicine, Beijing Hospital, Beijing, China
  18. 18National Center of Gerontology, Beijing Hospital, Beijing, China
  19. 19Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences; School of Basic Medicine, Peking Union Medical College, Beijing, China
  20. 20Center for Clinical Epidemiology and Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
  21. 21WHO Collaborating Center for Tobacco Cessation and Respiratory Diseases Prevention, Beijing, China
  22. 22Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
  23. 23National Heart & Lung Institute, Imperial College London, and Royal Brompton & Harefield NHS Trust, London, UK
  24. 24Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  1. Corresponding author: Chen Wang (wangchen{at}pumc.edu.cn)
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Funding

  • Special Research Foundation for Public welfare of Health, Ministry of Health of China

    201002008
  • ‘Summit’ talent training program, Beijing Hospital Authority

    DFL20190301
  • National Key R&D Program of China, Ministry of Science and Technology of China

    2016YFC0901100; 2016YFC0901102
  • National Natural Science Foundation of China

    81870032

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Prevalence and burden of chronic cough in China: a national cross-sectional study
Kewu Huang, Xiaoying Gu, Ting Yang, Jianying Xu, Lan Yang, Jianping Zhao, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen, Yahong Chen, Tieying Sun, Guangliang Shan, Yingxiang Lin, Sinan Wu, Ruiying Wang, Zhihong Shi, Yongjian Xu, Xianwei Ye, Yuanlin Song, Qiuyue Wang, Yumin Zhou, Wen Li, Liren Ding, Chun Wan, Wanzhen Yao, Yanfei Guo, Fei Xiao, Yong Lu, Xiaoxia Peng, Dan Xiao, Xiaoning Bu, Hong Zhang, Xiaolei Zhang, Li An, Shu Zhang, Zhixin Cao, Qingyuan Zhan, Yuanhua Yang, Lirong Liang, Huaping Dai, Bin Cao, Jiang He, Kian Fan Chung, Chen Wang
ERJ Open Research Jul 2022, 8 (3) 00075-2022; DOI: 10.1183/23120541.00075-2022

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Prevalence and burden of chronic cough in China: a national cross-sectional study
Kewu Huang, Xiaoying Gu, Ting Yang, Jianying Xu, Lan Yang, Jianping Zhao, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen, Yahong Chen, Tieying Sun, Guangliang Shan, Yingxiang Lin, Sinan Wu, Ruiying Wang, Zhihong Shi, Yongjian Xu, Xianwei Ye, Yuanlin Song, Qiuyue Wang, Yumin Zhou, Wen Li, Liren Ding, Chun Wan, Wanzhen Yao, Yanfei Guo, Fei Xiao, Yong Lu, Xiaoxia Peng, Dan Xiao, Xiaoning Bu, Hong Zhang, Xiaolei Zhang, Li An, Shu Zhang, Zhixin Cao, Qingyuan Zhan, Yuanhua Yang, Lirong Liang, Huaping Dai, Bin Cao, Jiang He, Kian Fan Chung, Chen Wang
ERJ Open Research Jul 2022, 8 (3) 00075-2022; DOI: 10.1183/23120541.00075-2022
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