BMI (kg·m−2) (n=62; NA=2) | | | | | | | | | |
Median (25th–75th centiles) | 24.25 | 22.2 | 25.1 | 26.55 | 22.82 | 22.0 | 25.8 | 24.8 | 22.8 |
| (21.8–26.7) | (20.9–28.7) | (23.7–25.6) | (24.3–28.3) | (19.9–25.8) | (21.1–25.4) | (21.9–26.5) | (23.1–28.4) | (21.0–26.5) |
Smoking history (n=58; NA=6) | | | | | | | | | |
No | 46 (79) | 6 (67) | 3 (50) | 8 (80) | 11 (85) | 10 (100) | 8 (80) | 17 (68) | 29 (88) |
Yes | 12 (21) | 3 (33) | 3 (50) | 2 (20) | 2 (15) | 0 (0) | 2 (20) | 8 (32) | 4 (12) |
Comorbidities, n |
(n=64; NA=0) | | | | | | | | | |
Median (25th–75th centiles) | 3.0 | 3.0 | 3.0 | 2.0 | 3.0 | 2.0 | 3.0 | 2.0 | 3.0 |
| (2.0–3.0) | (2.0–3.0) | (2.3–3.0) | (1.8–3.0) | (2.0–4.0) | (1.0–3.0) | (2.0–3.8) | (2.0–3.0) | (2.0–3.0) |
Polyposis (n=62; NA=2) | | | | | | | | | |
No | 28 (45) | 4 (44) | 1 (17) | 6 (50) | 6 (46) | 5 (39) | 6 (67) | 11 (41) | 17 (49) |
Yes | 34 (55) | 5 (56) | 5 (83) | 6 (50) | 7 (54) | 8 (62) | 3 (33) | 16 (59) | 18 (51) |
Bronchiectasis |
(n=57; NA=7) | | | | | | | | | |
No | 53 (93) | 9 (100) | 6 (100) | 10 (100) | 10 (83) | 8 (80) | 10 (100) | 25 (100) | 28 (88) |
Yes | 4 (7) | 0 (0) | 0 (0) | 0 (0) | 2 (17) | 2 (20) | 0 (0) | 0 (0) | 4 (13) |
Rhinitis (n=58; NA=6) | | | | | | | | | |
No | 4 (7) | 0 (0) | 0 (0) | 2 (20) | 0 (0) | 1 (10) | 1 (10) | 2 (8) | 2 (6) |
Yes | 54 (93) | 9 (100) | 6 (100) | 8 (80) | 13 (100) | 9 (90) | 9 (90) | 23 (92) | 31 (94) |
Atopy (n=59; NA=5) | | | | | | | | | |
No | 9 (15) | 0 (0) | 1 (17) | 2 (18) | 0 (0) | 4 (40) | 2 (20) | 3 (12) | 6 (18) |
Yes | 50 (85) | 9 (100) | 5 (83) | 9 (82) | 13 (100) | 6 (60) | 8 (80) | 23 (89) | 27 (82) |
Autoimmune diseases |
(n=58; NA=6) | | | | | | | | | |
No | 55 (95) | 9 (100) | 6 (100) | 10 (100) | 12 (92) | 9 (90) | 9 (90) | 25 (100) | 30 (91) |
Yes | 3 (5) | 0 (0) | 0 (0) | 0 (0) | 1 (8) | 1 (10) | 1 (10) | 0 (0) | 3 (9) |
Interstitial lung disease |
(n=58; NA=6) | | | | | | | | | |
No | 56 (97) | 9 (100) | 6 (100) | 10 (100) | 12 (92) | 9 (90) | 10 (100) | 25 (100) | 31 (94) |
Yes | 2 (3) | 0 (0) | 0 (0) | 0 (0) | 1 (8) | 1 (10) | 0 (0) | 0 (0) | 2 (6) |
Dermatitis (n=58; NA=6) | | | | | | | | | |
No | 56 (97) | 9 (100) | 6 (100) | 10 (100) | 12 (92) | 10 (100) | 9 (90) | 25 (100) | 31 (94) |
Yes | 2 (3) | 0 (0) | 0 (0) | 0 (0) | 1 (8) | 0 (0) | 1 (10) | 0 (0) | 2 (6) |
GERD (n=58; NA=6) | | | | | | | | | |
No | 47 (81) | 8 (89) | 6 (100) | 9 (90) | 10 (77) | 9 (90) | 5 (50) | 23 (92) | 24 (73) |
Yes | 11 (19) | 1 (11) | 0 (0) | 1 (10) | 3 (23) | 1 (10) | 5 (50) | 2 (8) | 9 (27) |
Biological drugs (n=61; NA=3) | | | | | | | | | |
Mepolizumab | 26 (43) | 2 (22) | 2 (33) | 6 (55) | 2 (15) | 10 (83) | 4 (40) | 10 (39) | 16 (46) |
Omalizumab | 35 (57) | 7 (78) | 4 (67) | 5 (46) | 11 (85) | 2 (17) | 6 (60) | 16 (62) | 19 (54) |
OCS (mg) (n=64; NA=0) | | | | | | | | | |
Median (25th–75th centiles) | 2.5 | 0.0 | 2.5 | 5.0 | 5.0 | 0.0 | 2.5 | 5.0 | 0.0 |
| (0.0–7.2) | (0.0–5.0) | (0.0–5.0) | (3.8–12.5) | (0.0–5.0) | (0.0–5.0) | (0.0–10.0) | (0.0–10.0) | (0.0–6.3) |
Blood eosinophils (cells·mm−3) |
(n=61; NA=3) | | | | | | | | | |
Median (25th–75th centiles) | 570.0 | 500.0 | 420.0 | 400.0 | 720.0 | 880.0 | 340.0 | 435.0 | 650.0 |
| (300.0–860.0) | (430.0–680.0) | (282.5–760.0) | (272.5–707.5) | (600.0–960.0) | (345.0–1080.0) | (272.5–552.5) | (275.0–702.5) | (320.0–1000.0) |
FENO (ppb) (n=61; NA=3) | | | | | | | | | |
Median (25th–75th centiles) | 48.2 | 41.4 | 59.0 | 55.4 | 37.12 | 74.0 | 39.66 | 45.0 | 49.0 |
| (28.2–87.5) | (34.7–45.0) | (30.3–83.9) | (29.6–89.3) | (27.4–92.2) | (57.0–99.8) | (20.3–48.0) | (30.9–79.7) | (27.1–93.0) |
FEV1 t0 (n=63; NA=1) | | | | | | | | | |
Median (25th–75th centiles) | 70.0 | 69.0 | 76.0 | 77.0 | 85.0 | 64.5 | 64.0 | 73.5 | 68.0 |
| (59.5–83.5) | (62.0–76.0) | (66.0–81.8) | (66.0–80.0) | (68.0–93.0) | (44.5–76.8) | (59.8–81.5) | (62.8–80.5) | (56.0–87.0) |
FVC t0 (n=63; NA=1) | | | | | | | | | |
Median (25th–75th centiles) | 86.0 | 83.0 | 92.0 | 85.0 | 88.0 | 75.5 | 88.0 | 84.0 | 88.0 |
| (73.0–98.5) | (65.0–92.0) | (79.3–109.3) | (80.5–88.0) | (69.0–103.0) | (63.3–94.5) | (87.3–96.3) | (77.5–92.8) | (69.0–103.0) |
Tiffeanu t0 (n=62; NA=2) | | | | | | | | | |
Median (25th–75th centiles) | 87.5 | 83.0 | 83.0 | 91.0 | 97.0 | 82.0 | 78.5 | 87.0 | 87.5 |
| (77.3–97.0) | (81.0–91.0) | (74.3–88.0) | (84.0–97.5) | (88.0–101.0) | (73.0–89.0) | (75.5–90.0) | (80.2–94.5) | (77.0–98.2) |
ACT t0 (n=62; NA=2) | | | | | | | | | |
Median (25th–75th centiles) | 17.0 | 18.0 | 16.0 | 18.0 | 15.0 | 17.0 | 18.5 | 18.0 | 17.0 |
| (15.0–19.0) | (15.0–18.0) | (14.5–20.5) | (16.0–20.5) | (13.0–17.0) | (15.0–19.0) | (17.0–24.0) | (15.2–19.0) | (14.8–19.0) |