Subjects n | | 485 | 460 | |
Sex, female | | 303 (62.5) | 223 (48.5) | <0.001 |
Age at study entry years, mean±sd | | 37.7±11.4 | 43.3±11.2 | <0.001 |
Age at follow-up years, mean±sd | | 56.6±12.3 | 61.4±11.9 | <0.001 |
Overweight/obese at follow-up | | 283 (58.4) | 442 (96.1) | <0.001 |
Smoking habits at study entry | | | | |
Nonsmoker | | 238 (49.1) | 186 (40.4) | |
Ex-smoker | | 113 (23.3) | 158 (34.3) | |
Smoker | | 134 (27.6) | 116 (25.2) | 0.001 |
Smoking habits at follow-up | | | | |
Nonsmoker | | 251 (51.8) | 202 (43.9) | |
Ex-smoker | | 177 (36.5) | 209 (45.4) | |
Smoker | | 57 (11.8) | 49 (10.7) | 0.019 |
Mean pack-years at follow-up, mean±sd# | | 16.5±14.9 | 17.6±16.6 | 0.436 |
ICS use at study entry | | 54 (11.1) | 61 (13.3) | 0.318 |
ICS use at follow-up | | 204 (42.1) | 211 (45.9) | 0.238 |