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Pathological characteristics of mediastinal masses in Sri Lanka 2017–2021: a retrospective observational study

Yasith Mathangasinghe, Saman Pradeep, Udeshika Perera, Ramani Punchihewa
ERJ Open Research 2022 8: 00256-2022; DOI: 10.1183/23120541.00256-2022
Yasith Mathangasinghe
1Department of Anatomy Genetics and Biomedical Informatics, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
2Australian Regenerative Medicine Institute, Monash University, Clayton, VIC, Australia
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  • ORCID record for Yasith Mathangasinghe
  • For correspondence: yasith@anat.cmb.ac.lk
Saman Pradeep
3Department of Thoracic Surgery, National Hospital for Respiratory Diseases, Welisara, Sri Lanka
4Royal Papworth Hospital, Cambridge Biomedical Campus, Cambridge, UK
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Udeshika Perera
5Cambridge University Hospital (Addenbrooke's Hospital), Cambridge, UK
6Castle Street Hospital for Women, Colombo, Sri Lanka
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Ramani Punchihewa
7Department of Pathology, National Hospital for Respiratory Diseases, Welisara, Sri Lanka
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Tables

  • TABLE 1

    Frequencies of sex and age of 550 consecutive mediastinal masses encountered in a 5-year period (2017–2021) at the National Hospital for Respiratory Diseases (Welisara, Sri Lanka)

    SubjectsSexAge (years)
    MaleFemaleRangeMean±sd
    Thymic lesions1711007112–8349±17
     Cyst107312–6838±18
     Hyperplasia146812–5928±15
     Thymolipoma1103434
     Thymoma114575715–8253±14
     Thymic carcinoma (type C)1917217–8352±19
     Carcinoid tumour1312119–7146±14
    Lymphoma/leukaemia100455511–7533±13
     Non-Hodgkin lymphoma56332311–7535±15
     Hodgkin lymphoma40122813–5929±10
     Unclassified40430–3835±4
    Infectious/inflammatory diseases75354017–7846±15
     Tuberculosis1741317–5933±13
     Sarcoidosis35171817–7450±12
     Granulomatous inflammation unclassified1912717–7850±15
     Rosai–Dorfman disease20217–3325±11
     Sinus histiocytosis22063–6363±0
    Germ-cell tumours6750173–5928±11
     Seminoma1111018–4325±9
     Teratoma3720173–5929±12
     Malignant nonseminimatous tumours191905–5327±12
    Metastasis58382020–7556±11
    Benign connective tissue tumours3418161–7247±20
     Castleman disease22034–5745±16
     Lipoma1016969
     Angioma32125–7152±24
     Schwannoma2113823–7251±15
     Neurofibroma1015656
     Ganglioneuroma6151–6426±25
    Developmental cysts136719–6649±16
     Bronchogenic74319–5840±15
     Pleuro-pericardial21142–6453±16
     Unclassified41359–6663±3
    Sarcoma28111718–7342±16
    Other unclassified tumours4135–4424±16

    Data are presented as n, unless otherwise stated.

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    Pathological characteristics of mediastinal masses in Sri Lanka 2017–2021: a retrospective observational study
    Yasith Mathangasinghe, Saman Pradeep, Udeshika Perera, Ramani Punchihewa
    ERJ Open Research Oct 2022, 8 (4) 00256-2022; DOI: 10.1183/23120541.00256-2022

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    Pathological characteristics of mediastinal masses in Sri Lanka 2017–2021: a retrospective observational study
    Yasith Mathangasinghe, Saman Pradeep, Udeshika Perera, Ramani Punchihewa
    ERJ Open Research Oct 2022, 8 (4) 00256-2022; DOI: 10.1183/23120541.00256-2022
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