Abstract
The low adherence of children with bronchial asthma (BA) to long-term control treatment is partly associated with the patients’ fear of systemic effect of inhaled corticosteroids (ICS). The aim: to evaluate the physical development of children who have had background long-standing therapy of asthma by ICS. At the Regional children clinical hospital in Chernivtsi 50 school-aged patients with persistent BA have been examined. The assessment of physical development with the calculation of the body mass index (BMI) of patients has been done by a centile method. In the I group 21 patients under the long-term usage of low/medium doses of ICS were enrolled, the II group consisted of 29 patients who used high-dose ICS to control asthma. Patients of the II group have received high-dose ICS significantly longer (6.7±0.7 years) relatively to patients of the I group (4.2±0.7 years, P <0.05). In spite of the fact that short stature (growth with respect to age <10 percentile) has been registered in children who received high-dose ICS twice as frequently (10.3%) as patients of the I group (4.8%), this difference was statistically insignificant (P> 0.05). Although obesity (BMI> 25 kg/m2) has been registered three times more often in patients of II group (13.8%) than in the I group (4.8%; P> 0.05), the correlation analysis did not reveal statistically significant relationship between overweight (according to BMI) and the duration of high-dose ICS use (r=0.16; P=0.42). At that, prolonged backround therapy by low/medium or high-dose ICS had not had statistically significant influence on the physical development of the school-aged asthma patients.
Footnotes
Cite this article as ERJ Open Research 2022; 8: Suppl. 8, 148.
This article was presented at the 2022 ERS Lung Science Conference, in session “Poster Session 2”.
This is an ERS Lung Science Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2022