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Single cell transcriptomic dissection of virus induced immunopathology in interferon gamma receptor null mice

Lin Yang, Ilias Angelidis, Lukas Heumos, Mesha Ansari, Shuhong Zhou, Christoph Mayr, Lukas Simon, Maximilian Strunz, Fabian Theis, Heiko Adler, Herbert Schiller
ERJ Open Research 2022 8: 36; DOI: 10.1183/23120541.LSC-2022.36
Lin Yang
1Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany, Munich, Germany
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  • For correspondence: lin.yang@helmholtz-muenchen.de
Ilias Angelidis
1Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany, Munich, Germany
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Lukas Heumos
2Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany; School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany, Munich, Germany
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Mesha Ansari
3Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany, Munich, Germany
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Shuhong Zhou
1Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany, Munich, Germany
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Christoph Mayr
1Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany, Munich, Germany
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Lukas Simon
1Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany, Munich, Germany
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Maximilian Strunz
1Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany, Munich, Germany
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Fabian Theis
4Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany, Munich, Germany
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Heiko Adler
5Research Unit Lung Repair and Regeneration, Helmholtz Zentrum München, Munich, Germany; Member of the German Center for Lung Research (DZL), Munich, Germany
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Herbert Schiller
1Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany, Munich, Germany
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Article Information

vol. 8 no. suppl 8
DOI 
https://doi.org/10.1183/23120541.LSC-2022.36

Published By 
European Respiratory Society
Online ISSN 
2312-0541
History 
  • Published online May 9, 2022.

Copyright & Usage 
Copyright ©the authors 2022

Author Information

  1. Lin Yang1⇑,
  2. Ilias Angelidis1,
  3. Lukas Heumos2,
  4. Mesha Ansari3,
  5. Shuhong Zhou1,
  6. Christoph Mayr1,
  7. Lukas Simon1,
  8. Maximilian Strunz1,
  9. Fabian Theis4,
  10. Heiko Adler5 and
  11. Herbert Schiller1
  1. 1Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany, Munich, Germany
  2. 2Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany; School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany, Munich, Germany
  3. 3Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany; Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany, Munich, Germany
  4. 4Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany, Munich, Germany
  5. 5Research Unit Lung Repair and Regeneration, Helmholtz Zentrum München, Munich, Germany; Member of the German Center for Lung Research (DZL), Munich, Germany
  1. Lin Yang, Comprehensive Pneumology Center (CPC) / Institute for Lung Biology and Disease (ILBD); Member of the German Center for Lung Research (DZL), Helmholtz Zentrum München, Munich, Germany, Munich, Germany. E-mail: lin.yang{at}helmholtz-muenchen.de

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Single cell transcriptomic dissection of virus induced immunopathology in interferon gamma receptor null mice
Lin Yang, Ilias Angelidis, Lukas Heumos, Mesha Ansari, Shuhong Zhou, Christoph Mayr, Lukas Simon, Maximilian Strunz, Fabian Theis, Heiko Adler, Herbert Schiller
ERJ Open Research Mar 2022, 8 (suppl 8) 36; DOI: 10.1183/23120541.LSC-2022.36

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Single cell transcriptomic dissection of virus induced immunopathology in interferon gamma receptor null mice
Lin Yang, Ilias Angelidis, Lukas Heumos, Mesha Ansari, Shuhong Zhou, Christoph Mayr, Lukas Simon, Maximilian Strunz, Fabian Theis, Heiko Adler, Herbert Schiller
ERJ Open Research Mar 2022, 8 (suppl 8) 36; DOI: 10.1183/23120541.LSC-2022.36
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