Abstract
Aims/Objectives: The outcome of prolonged weaning in COPD-patients is still unclear.
Methods: A subgroup analysis of 2937 COPD-patients (median: age 69 years, 5 co-morbidities, 43% female) from the entire WeanNet cohort of specialized German weaning centers previously published (N=11424) was performed.
Results: Successful weaning without subsequent long-term non-invasive ventilation (NIV): N=900; 30.6%; successful weaning with subsequent long-term NIV: N=900; 30.6%; weaning failure with subsequent long-term invasive ventilation: N=780; 26.6%; and death: N=357; 12.2%. Most important predictors of mortality and weaning failure were advanced age and duration of mechanical ventilation in the transferring ICU. On discharge, the tracheostoma was closed in only 53% and 59% of patients with successful weaning not receiving and receiving long-term NIV. Unsuccessfully weaned patients were predominantly discharged home (20.5%) or to long-term care facilities (57.2%). Successfully weaned patients were predominantly discharged home (22.4%/35.9%: without/with NIV) and to rehabilitation (41.0%/43.1%: without/with NIV) (Fig.1).
Conclusion: COPD forms an important subgroup of prolonged weaning patients. Following transfer from the ICU to a specialized weaning center, weaning is successful more than 60%. Importantly, both tracheostomy status and initial destination following discharge are highly dependent on weaning outcome.
Footnotes
Cite this article as: ERJ Open Research 2022; 8: Suppl. 9, 3.
This article was presented at the 2022 ERS Respiratory Failure and Mechanical Ventilation Conference, in session “Poster Session 2”.
This is an ERS Respiratory Failure and Mechanical Ventilation Conference abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
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