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COVID-19 in patients with pulmonary alveolar proteinosis: a European multicentre study

Spyros A. Papiris, Ilaria Campo, Francesca Mariani, Maria Kallieri, Lykourgos Kolilekas, Andriana I. Papaioannou, Efsun Gonca Chousein, Erdogan Cetinkaya, Francesco Bonella, Raphael Borie, Maria Kokosi, Thomas Pickworth, Maria Molina-Molina, Mercè Gasa, Elżbieta Radzikowska, Justyna Fijolek, Stéphane Jouneau, Emmanuel Gomez, Cormac McCarthy, Elisabeth Bendstrup, Wojciech J. Piotrowski, Rishi Pabary, Alice Hadchouel, Nathalie Coolen-Allou, Tiago Alfaro, Carlos Robalo Cordeiro, Elvira-Markela Antonogiannaki, Ioannis P. Tomos, Despoina Papakosta, Theodoros Kontakiotis, Panagiota Panagiotou, Konstantinos Douros, Andrea Schams, Sara Lettieri, Vassiliki Papaevangelou, Christina Kanaka-Gantenbein, Anna Karakatsani, Stelios Loukides, Ulrich Costabel, Bruno Crestani, Cliff Morgan, Ryushi Tazawa, Andrew Bush, Matthias Griese, Effrosyni D. Manali
ERJ Open Research 2023 9: 00199-2022; DOI: 10.1183/23120541.00199-2022
Spyros A. Papiris
1General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Ilaria Campo
2Laboratorio di Biochimica e Genetica, UOC Pneumologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
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  • ORCID record for Ilaria Campo
Francesca Mariani
2Laboratorio di Biochimica e Genetica, UOC Pneumologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
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Maria Kallieri
1General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Lykourgos Kolilekas
37th Pulmonary Dept, Athens Chest Hospital “Sotiria”, Athens, Greece
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Andriana I. Papaioannou
1General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Efsun Gonca Chousein
4University of Health Sciences Turkey, Yedikule Chest Diseases and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey
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Erdogan Cetinkaya
4University of Health Sciences Turkey, Yedikule Chest Diseases and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey
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Francesco Bonella
5Center for Interstitial and Rare Lung Diseases, Pneumology Dept, Ruhrlandklinik, University Hospital, University of Essen, Essen, Germany; European Reference Network (ERN)-LUNG, ILD Core Net
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  • ORCID record for Francesco Bonella
Raphael Borie
6Université de Paris, INSERM UMR 1152, APHP, Hôpital Bichat, Service de Pneumologie A, FHU APOLLO, Centre de référence des maladies pulmonaires rares, Paris, France
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Maria Kokosi
7Interstitial Lung Disease Unit, Royal Brompton Hospital & Harefield NHS Foundation Trust and Interstitial Lung Disease Unit, Guy's and St Thomas’ Hospital NHS Foundation Trust, London, UK
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Thomas Pickworth
8Dept of Anaesthesia, Royal Brompton Hospital, London, UK
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Maria Molina-Molina
9ILD Multidisciplinary Unit, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet del Llobregat, Barcelona, Spain
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Mercè Gasa
9ILD Multidisciplinary Unit, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet del Llobregat, Barcelona, Spain
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Elżbieta Radzikowska
103rd Dept of Lung Diseases and Oncology, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland
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  • ORCID record for Elżbieta Radzikowska
Justyna Fijolek
103rd Dept of Lung Diseases and Oncology, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland
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Stéphane Jouneau
11IRSET UMR 1085, Université de Rennes Service de Pneumologie, CHU de Rennes, Rennes, France
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  • ORCID record for Stéphane Jouneau
Emmanuel Gomez
12Pneumologie, CHU de Nancy, Nancy, France
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Cormac McCarthy
13University College Dublin School of Medicine Education and Research Centre, St Vincent's University Hospital, Dublin, Ireland
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Elisabeth Bendstrup
14Center for Rare Lung diseases, Dept of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark
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Wojciech J. Piotrowski
15Dept of Pneumonology, 2nd Chair of Internal Medicine, Medical University of Lodz, Lodz, Poland
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Rishi Pabary
16Paediatrics and Paediatric Respirology, Imperial College and Imperial Centre for Paediatrics and Child Health, Royal Brompton & Harefield NHS Foundation Trust, London, UK
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Alice Hadchouel
17AP-HP, Hôpital Necker-Enfants Malades, Service de Pneumologie Pédiatrique, Centre de Référence pour les Maladies Respiratoires Rares de l'Enfant and INSERM U1151, Institut Necker Enfants Malades, Université de Paris, Faculté de Médecine, Paris, France
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Nathalie Coolen-Allou
18Service de Pneumologie Hôpital Félix Guyon, CHU Réunion, Reunion, France
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Tiago Alfaro
19Dept of Pulmonology, Coimbra University Hospital, University of Coimbra, Coimbra, Portugal
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Carlos Robalo Cordeiro
19Dept of Pulmonology, Coimbra University Hospital, University of Coimbra, Coimbra, Portugal
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Elvira-Markela Antonogiannaki
1General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Ioannis P. Tomos
1General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Despoina Papakosta
20Dept of Pulmonary Medicine, Aristotle University of Thessaloniki, “G. Papanikolaou” Hospital, Exochi, Thessaloniki, Greece
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Theodoros Kontakiotis
20Dept of Pulmonary Medicine, Aristotle University of Thessaloniki, “G. Papanikolaou” Hospital, Exochi, Thessaloniki, Greece
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Panagiota Panagiotou
21First Dept of Paediatrics, Agia Sophia Children's Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Konstantinos Douros
22Third Dept of Pediatrics “Attikon” University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
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Andrea Schams
23Dept of Pediatric Pneumology, Dr von Hauner Children's Hospital, Ludwig-Maximilians-University, German Center for Lung Research, Munich, Germany
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Sara Lettieri
2Laboratorio di Biochimica e Genetica, UOC Pneumologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
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Vassiliki Papaevangelou
22Third Dept of Pediatrics “Attikon” University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
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Christina Kanaka-Gantenbein
21First Dept of Paediatrics, Agia Sophia Children's Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Anna Karakatsani
1General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Stelios Loukides
1General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Ulrich Costabel
5Center for Interstitial and Rare Lung Diseases, Pneumology Dept, Ruhrlandklinik, University Hospital, University of Essen, Essen, Germany; European Reference Network (ERN)-LUNG, ILD Core Net
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Bruno Crestani
6Université de Paris, INSERM UMR 1152, APHP, Hôpital Bichat, Service de Pneumologie A, FHU APOLLO, Centre de référence des maladies pulmonaires rares, Paris, France
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Cliff Morgan
7Interstitial Lung Disease Unit, Royal Brompton Hospital & Harefield NHS Foundation Trust and Interstitial Lung Disease Unit, Guy's and St Thomas’ Hospital NHS Foundation Trust, London, UK
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Ryushi Tazawa
24Health Administration Center, Tokyo Medical and Dental University, Tokyo, Japan
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Andrew Bush
16Paediatrics and Paediatric Respirology, Imperial College and Imperial Centre for Paediatrics and Child Health, Royal Brompton & Harefield NHS Foundation Trust, London, UK
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Matthias Griese
23Dept of Pediatric Pneumology, Dr von Hauner Children's Hospital, Ludwig-Maximilians-University, German Center for Lung Research, Munich, Germany
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Effrosyni D. Manali
1General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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  • For correspondence: fmanali@otenet.gr
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Article Information

vol. 9 no. 1
DOI 
https://doi.org/10.1183/23120541.00199-2022

Published By 
European Respiratory Society
Online ISSN 
2312-0541
History 
  • Received April 26, 2022
  • Accepted May 23, 2022
  • Published online January 3, 2023.

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  • previous version (July 28, 2022 - 08:55).
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Copyright ©The authors 2023 This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org

Author Information

  1. Spyros A. Papiris1,
  2. Ilaria Campo2,
  3. Francesca Mariani2,
  4. Maria Kallieri1,
  5. Lykourgos Kolilekas3,
  6. Andriana I. Papaioannou1,
  7. Efsun Gonca Chousein4,
  8. Erdogan Cetinkaya4,
  9. Francesco Bonella5,
  10. Raphael Borie6,
  11. Maria Kokosi7,
  12. Thomas Pickworth8,
  13. Maria Molina-Molina9,
  14. Mercè Gasa9,
  15. Elżbieta Radzikowska10,
  16. Justyna Fijolek10,
  17. Stéphane Jouneau11,
  18. Emmanuel Gomez12,
  19. Cormac McCarthy13,
  20. Elisabeth Bendstrup14,
  21. Wojciech J. Piotrowski15,
  22. Rishi Pabary16,
  23. Alice Hadchouel17,
  24. Nathalie Coolen-Allou18,
  25. Tiago Alfaro19,
  26. Carlos Robalo Cordeiro19,
  27. Elvira-Markela Antonogiannaki1,
  28. Ioannis P. Tomos1,
  29. Despoina Papakosta20,
  30. Theodoros Kontakiotis20,
  31. Panagiota Panagiotou21,
  32. Konstantinos Douros22,
  33. Andrea Schams23,
  34. Sara Lettieri2,
  35. Vassiliki Papaevangelou22,
  36. Christina Kanaka-Gantenbein21,
  37. Anna Karakatsani1,
  38. Stelios Loukides1,
  39. Ulrich Costabel5,
  40. Bruno Crestani6,
  41. Cliff Morgan7,
  42. Ryushi Tazawa24,
  43. Andrew Bush16,
  44. Matthias Griese23 and
  45. Effrosyni D. Manali1⇑
  1. 1General University Hospital “Attikon”, Medical School, National and Kapodistrian University of Athens, Athens, Greece
  2. 2Laboratorio di Biochimica e Genetica, UOC Pneumologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
  3. 37th Pulmonary Dept, Athens Chest Hospital “Sotiria”, Athens, Greece
  4. 4University of Health Sciences Turkey, Yedikule Chest Diseases and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey
  5. 5Center for Interstitial and Rare Lung Diseases, Pneumology Dept, Ruhrlandklinik, University Hospital, University of Essen, Essen, Germany; European Reference Network (ERN)-LUNG, ILD Core Net
  6. 6Université de Paris, INSERM UMR 1152, APHP, Hôpital Bichat, Service de Pneumologie A, FHU APOLLO, Centre de référence des maladies pulmonaires rares, Paris, France
  7. 7Interstitial Lung Disease Unit, Royal Brompton Hospital & Harefield NHS Foundation Trust and Interstitial Lung Disease Unit, Guy's and St Thomas’ Hospital NHS Foundation Trust, London, UK
  8. 8Dept of Anaesthesia, Royal Brompton Hospital, London, UK
  9. 9ILD Multidisciplinary Unit, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet del Llobregat, Barcelona, Spain
  10. 103rd Dept of Lung Diseases and Oncology, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland
  11. 11IRSET UMR 1085, Université de Rennes Service de Pneumologie, CHU de Rennes, Rennes, France
  12. 12Pneumologie, CHU de Nancy, Nancy, France
  13. 13University College Dublin School of Medicine Education and Research Centre, St Vincent's University Hospital, Dublin, Ireland
  14. 14Center for Rare Lung diseases, Dept of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark
  15. 15Dept of Pneumonology, 2nd Chair of Internal Medicine, Medical University of Lodz, Lodz, Poland
  16. 16Paediatrics and Paediatric Respirology, Imperial College and Imperial Centre for Paediatrics and Child Health, Royal Brompton & Harefield NHS Foundation Trust, London, UK
  17. 17AP-HP, Hôpital Necker-Enfants Malades, Service de Pneumologie Pédiatrique, Centre de Référence pour les Maladies Respiratoires Rares de l'Enfant and INSERM U1151, Institut Necker Enfants Malades, Université de Paris, Faculté de Médecine, Paris, France
  18. 18Service de Pneumologie Hôpital Félix Guyon, CHU Réunion, Reunion, France
  19. 19Dept of Pulmonology, Coimbra University Hospital, University of Coimbra, Coimbra, Portugal
  20. 20Dept of Pulmonary Medicine, Aristotle University of Thessaloniki, “G. Papanikolaou” Hospital, Exochi, Thessaloniki, Greece
  21. 21First Dept of Paediatrics, Agia Sophia Children's Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
  22. 22Third Dept of Pediatrics “Attikon” University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
  23. 23Dept of Pediatric Pneumology, Dr von Hauner Children's Hospital, Ludwig-Maximilians-University, German Center for Lung Research, Munich, Germany
  24. 24Health Administration Center, Tokyo Medical and Dental University, Tokyo, Japan
  1. Effrosyni Manali (fmanali{at}otenet.gr)
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COVID-19 in patients with pulmonary alveolar proteinosis: a European multicentre study
Spyros A. Papiris, Ilaria Campo, Francesca Mariani, Maria Kallieri, Lykourgos Kolilekas, Andriana I. Papaioannou, Efsun Gonca Chousein, Erdogan Cetinkaya, Francesco Bonella, Raphael Borie, Maria Kokosi, Thomas Pickworth, Maria Molina-Molina, Mercè Gasa, Elżbieta Radzikowska, Justyna Fijolek, Stéphane Jouneau, Emmanuel Gomez, Cormac McCarthy, Elisabeth Bendstrup, Wojciech J. Piotrowski, Rishi Pabary, Alice Hadchouel, Nathalie Coolen-Allou, Tiago Alfaro, Carlos Robalo Cordeiro, Elvira-Markela Antonogiannaki, Ioannis P. Tomos, Despoina Papakosta, Theodoros Kontakiotis, Panagiota Panagiotou, Konstantinos Douros, Andrea Schams, Sara Lettieri, Vassiliki Papaevangelou, Christina Kanaka-Gantenbein, Anna Karakatsani, Stelios Loukides, Ulrich Costabel, Bruno Crestani, Cliff Morgan, Ryushi Tazawa, Andrew Bush, Matthias Griese, Effrosyni D. Manali
ERJ Open Research Jan 2023, 9 (1) 00199-2022; DOI: 10.1183/23120541.00199-2022

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COVID-19 in patients with pulmonary alveolar proteinosis: a European multicentre study
Spyros A. Papiris, Ilaria Campo, Francesca Mariani, Maria Kallieri, Lykourgos Kolilekas, Andriana I. Papaioannou, Efsun Gonca Chousein, Erdogan Cetinkaya, Francesco Bonella, Raphael Borie, Maria Kokosi, Thomas Pickworth, Maria Molina-Molina, Mercè Gasa, Elżbieta Radzikowska, Justyna Fijolek, Stéphane Jouneau, Emmanuel Gomez, Cormac McCarthy, Elisabeth Bendstrup, Wojciech J. Piotrowski, Rishi Pabary, Alice Hadchouel, Nathalie Coolen-Allou, Tiago Alfaro, Carlos Robalo Cordeiro, Elvira-Markela Antonogiannaki, Ioannis P. Tomos, Despoina Papakosta, Theodoros Kontakiotis, Panagiota Panagiotou, Konstantinos Douros, Andrea Schams, Sara Lettieri, Vassiliki Papaevangelou, Christina Kanaka-Gantenbein, Anna Karakatsani, Stelios Loukides, Ulrich Costabel, Bruno Crestani, Cliff Morgan, Ryushi Tazawa, Andrew Bush, Matthias Griese, Effrosyni D. Manali
ERJ Open Research Jan 2023, 9 (1) 00199-2022; DOI: 10.1183/23120541.00199-2022
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