Table of Contents

Original research articles

• Respiratory infections

  • Open Access

    Incorporation of biomarkers into a prediction model for paediatric radiographic pneumonia

    Sriram Ramgopal, Lilliam Ambroggio, Douglas Lorenz, Samir S. Shah, Richard M. Ruddy, Todd A. Florin

    ERJ Open Res 9: 00339-2022; DOI: 10.1183/23120541.00339-2022 Published 6 March 2023
  • Open Access

    The use of continuous positive airway pressure during the second and third waves of the COVID-19 pandemic

    Claudia Brusasco, Francesco Corradi, Federico Dazzi, Alessandro Isirdi, Chiara Romei, Andrea Parisini, Silvia Boni, Gregorio Santori, Vito Brusasco, the Galliera CPAP-COVID-19 study group, the Galliera CPAP-COVID-19 study group , C. Brusasco, F. Corradi, C. Brusasco, A. Isirdi, F. Dazzi, V. Brusasco, A. Parisini, S. Boni, G. Santori, A. Parisini, S. Boni, F. Corradi, C. Brusasco, C. Romei, F. Corradi, C. Brusasco, V. Brusasco, F. Corradi, C. Brusasco, G. Santori, F. Dazzi

    ERJ Open Res 9: 00365-2022; DOI: 10.1183/23120541.00365-2022 Published 6 March 2023
  • Open Access

    A prospective study of pulmonary outcomes and chest computed tomography in the first year after COVID-19

    Tøri Vigeland Lerum, Carin Meltzer, Jezabel Riverio Rodriguez, Trond Mogens Aaløkken, Eivind Brønstad, Bernt B. Aarli, Kristine Marie Aarberg-Lund, Michael T. Durheim, Haseem Ashraf, Gunnar Einvik, Ole Henning Skjønsberg, Knut Stavem

    ERJ Open Res 9: 00575-2022; DOI: 10.1183/23120541.00575-2022 Published 13 March 2023
  • Open Access

    Pathogen spectra in hospitalised and nonhospitalised children with community-acquired pneumonia

    Martin Wetzke, Katharina Schütz, Matthias Volkmar Kopp, Jürgen Seidenberg, Christian Vogelberg, Tobias Ankermann, Christine Happle, Gesche Voigt, Holger Köster, Thomas Illig, Christiane Lex, Antje Schuster, Ralph Maier, Marcus Panning, Grit Barten, Gernot Rohde, Tobias Welte, Gesine Hansen

    ERJ Open Res 9: 00286-2022; DOI: 10.1183/23120541.00286-2022 Published 13 March 2023
  • Open Access

    COVID-19 and its continuing burden after 12 months: a longitudinal observational prospective multicentre trial

    Sabina Sahanic, Piotr Tymoszuk, Anna K. Luger, Katharina Hüfner, Anna Boehm, Alex Pizzini, Christoph Schwabl, Sabine Koppelstätter, Katharina Kurz, Malte Asshoff, Birgit Mosheimer-Feistritzer, Maximilian Coen, Bernhard Pfeifer, Verena Rass, Alexander Egger, Gregor Hörmann, Barbara Sperner-Unterweger, Raimund Helbok, Ewald Wöll, Günter Weiss, Gerlig Widmann, Ivan Tancevski, Thomas Sonnweber, Judith Löffler-Ragg

    ERJ Open Res 9: 00317-2022; DOI: 10.1183/23120541.00317-2022 Published 13 March 2023
  • Open Access

    Group-based pulmonary telerehabilitation is feasible, safe, beneficial and well-received in patients who have been hospitalised with COVID-19

    Andrew J. Simpson, Angela Green, Marion Nettleton, Lucy Hyde, Joanne Shepherdson, Clare Killingback, Phil Marshall, Michael G. Crooks

    ERJ Open Res 9: 00373-2022; DOI: 10.1183/23120541.00373-2022 Published 13 March 2023
  • Open Access

    Molecular assessment of mycobacterial burden in the treatment of nontuberculous mycobacterial disease

    Huw C. Ellis, Miriam F. Moffatt, Colin Churchward, Leah Cuthbertson, William O.C. Cookson, Michael R. Loebinger

    ERJ Open Res 9: 00435-2022; DOI: 10.1183/23120541.00435-2022 Published 20 March 2023

• Asthma

  • Open Access

    The impact of anti-eosinophilic therapy on exercise capacity and inspiratory muscle strength in patients with severe asthma

    Elisa Franceschi, Nora Drick, Jan Fuge, Pierachille Santus, Bettina Fischer, Moritz Kayser, Tobias Welte, Hendrik Suhling

    ERJ Open Res 9: 00341-2022; DOI: 10.1183/23120541.00341-2022 Published 20 March 2023
  • Open Access

    Distribution of type 2 biomarkers and association with severity, clinical characteristics and comorbidities in the BREATHE real-life asthma population

    Laurits Frøssing, Ditte K. Klein, Morten Hvidtfeldt, Nicolai Obling, Gunilla Telg, Jonas S. Erjefält, Uffe Bodtger, Celeste Porsbjerg

    ERJ Open Res 9: 00483-2022; DOI: 10.1183/23120541.00483-2022 Published 20 March 2023

• COPD

  • Open Access

    Prime-boost, double-dose influenza vaccine immunity in COPD: a pilot observational study

    Gary P. Anderson, Louis B. Irving, Andrew Jarnicki, Katherine Kedzierska, Marios Koutsakos, Stephen Kent, Aeron C. Hurt, Adam K. Wheatley, Thi H.O. Nguyen, Natale Snape, John W. Upham

    ERJ Open Res 9: 00641-2021; DOI: 10.1183/23120541.00641-2021 Published 6 March 2023
  • Open Access

    Dynamic analysis of gene signatures in the progression of COPD

    Junchao Jiang, Shengsong Chen, Tao Yu, Chenli Chang, Jixiang Liu, Xiaoxia Ren, Hongtao Niu, Ke Huang, Baicun Li, Chen Wang, Ting Yang

    ERJ Open Res 9: 00343-2022; DOI: 10.1183/23120541.00343-2022 Published 6 March 2023
  • Open Access

    Low-density lipoprotein cholesterol and risk of COPD: Copenhagen General Population Study

    Josefine Freyberg, Eskild M. Landt, Shoaib Afzal, Børge G. Nordestgaard, Morten Dahl

    ERJ Open Res 9: 00496-2022; DOI: 10.1183/23120541.00496-2022 Published 6 March 2023
  • Open Access

    Comparison of two scores for short-term outcomes in patients with COPD exacerbation in the emergency department: the Ottawa COPD Risk Scale and the DECAF score

    Ali Unal, Basak Bayram, Begum Ergan, Kazim Can, Yagiz Kagan Ergun, Oguz Kilinc

    ERJ Open Res 9: 00436-2022; DOI: 10.1183/23120541.00436-2022 Published 13 March 2023
  • Open Access

    Hypoxia-altitude simulation test to predict altitude-related adverse health effects in COPD patients

    Meret Bauer, Julian Müller, Simon R. Schneider, Simone Buenzli, Michael Furian, Tanja Ulrich, Arcangelo F. Carta, Patrick R. Bader, Mona Lichtblau, Ajian Taalaibekova, Madiiar Raimberdiev, Benoit Champigneulle, Talant Sooronbaev, Konrad E. Bloch, Silvia Ulrich

    ERJ Open Res 9: 00488-2022; DOI: 10.1183/23120541.00488-2022 Published 13 March 2023

• ɑ1-antitrypsin deficiency

  • Open Access

    The effect of exacerbations on lung density in α₁-antitrypsin deficiency

    Charlie Strange, N. Gerard McElvaney, Claus F. Vogelmeier, Marcos Marin-Galiano, Michaela Buch-Haensel, Xiang Zhang, Younan Chen, Oliver Vit, Marion Wencker, Kenneth R. Chapman

    ERJ Open Res 9: 00457-2022; DOI: 10.1183/23120541.00457-2022 Published 13 March 2023

• Pulmonary vascular disease

  • Open Access

    Decreased plasma levels of the brain-derived neurotrophic factor correlate with right heart congestion in pulmonary arterial hypertension

    Katharina Schäfer, Khodr Tello, Oleg Pak, Manuel Richter, Mareike Gierhardt, Grazyna Kwapiszewska, Christine Veith, Ludger Fink, Henning Gall, Matthias Hecker, Baktybek Kojonazarov, Simone Kraut, Kevin Lo, Jochen Wilhelm, Friedrich Grimminger, Werner Seeger, Ralph T. Schermuly, Hossein A. Ghofrani, Daniel Zahner, Rüdiger Gerstberger, Norbert Weissmann, Akylbek Sydykov, Natascha Sommer

    ERJ Open Res 9: 00230-2022; DOI: 10.1183/23120541.00230-2022 Published 6 March 2023
  • Open Access

    AV-101, a novel inhaled dry-powder formulation of imatinib, in healthy adult participants: a phase 1 single and multiple ascending dose study

    Hunter Gillies, Ralph Niven, Benjamin T. Dake, Murali M. Chakinala, Jeremy P. Feldman, Nicholas S. Hill, Marius M. Hoeper, Marc Humbert, Vallerie V. McLaughlin, Martin Kankam

    ERJ Open Res 9: 00433-2022; DOI: 10.1183/23120541.00433-2022 Published 13 March 2023
  • Open Access

    Clinical phenotyping of plasma thrombospondin-2 reveals relationship to right ventricular structure and function in pulmonary hypertension

    Anna M. Dittrich, Julia Mienert, Julian Pott, Lena Engels, Christoph Sinning, Jan K. Hennigs, Hans Klose, Lars Harbaum

    ERJ Open Res 9: 00528-2022; DOI: 10.1183/23120541.00528-2022 Published 13 March 2023

• Thoracic tumours

  • Open Access

    The risk of post-operative pulmonary complications in lung resection candidates with normal forced expiratory volume in 1 s and diffusing capacity of the lung for carbon monoxide: a prospective multicentre study

    Ivan Cundrle, Zdenek Merta, Monika Bratova, Pavel Homolka, Ladislav Mitas, Vladimir Sramek, Michal Svoboda, Zdenek Chovanec, Milos Chobola, Lyle J. Olson, Kristian Brat

    ERJ Open Res 9: 00421-2022; DOI: 10.1183/23120541.00421-2022 Published 6 March 2023

• Sleep medicine

  • Open Access

    Short-term cognitive loading deteriorates breathing pattern and gas exchange in adult patients with congenital central hypoventilation syndrome

    Jessica Taytard, Marie-Cécile Niérat, Camille Gand, Sophie Lavault, Capucine Morélot-Panzini, Maxime Patout, Laure Serresse, Nicolas Wattiez, Laurence Bodineau, Christian Straus, Thomas Similowski

    ERJ Open Res 9: 00408-2022; DOI: 10.1183/23120541.00408-2022 Published 13 March 2023

• Interstitial lung disease

  • Open Access

    Nintedanib for non-IPF progressive pulmonary fibrosis: 12-month outcome data from a real-world multicentre observational study

    Lavanya Raman, Iain Stewart, Shaney L. Barratt, Felix Chua, Nazia Chaudhuri, Anjali Crawshaw, Michael Gibbons, Charlotte Hogben, Rachel Hoyles, Vasilis Kouranos, Jennifer Martinovic, Sarah Mulholland, Katherine J. Myall, Marium Naqvi, Elisabetta A. Renzoni, Peter Saunders, Matthew Steward, Dharmic Suresh, Muhunthan Thillai, Athol U. Wells, Alex West, Jane A. Mitchell, Peter M. George

    ERJ Open Res 9: 00423-2022; DOI: 10.1183/23120541.00423-2022 Published 20 March 2023

• Bronchiectasis

  • Open Access

    Airway clearance treatments in bronchiectasis: feasibility of linking survey results to registry data and a survey of patients’ and physiotherapists’ practices

    Rebecca H. McLeese, Katherine O'Neill, Brenda O'Neill, James D. Chalmers, Jeanette Boyd, Anthony De Soyza, Ryan McChrystal, Megan L. Crichton, Judy M. Bradley

    ERJ Open Res 9: 00540-2022; DOI: 10.1183/23120541.00540-2022 Published 20 March 2023

• Pulmonary oxidative injury

  • Open Access

    Validation of volatile metabolites of pulmonary oxidative injury: a bench to bedside study

    Dominic Fenn, Thijs A. Lilien, Laura A. Hagens, Marry R. Smit, Nanon F.L. Heijnen, Anita M. Tuip-de Boer, Anne H. Neerincx, Korneliusz Golebski, Dennis C.J.J. Bergmans, Ronny M. Schnabel, Marcus J. Schultz, Anke H. Maitland-van der Zee, Paul Brinkman, Lieuwe D.J. Bos

    ERJ Open Res 9: 00427-2022; DOI: 10.1183/23120541.00427-2022 Published 20 March 2023

• HIV-associated obstructive lung disease

  • Open Access

    Lung proteome and metabolome endotype in HIV-associated obstructive lung disease

    Sarah Samorodnitsky, Eric F. Lock, Monica Kruk, Alison Morris, Janice M. Leung, Ken M. Kunisaki, Timothy J. Griffin, Chris H. Wendt

    ERJ Open Res 9: 00332-2022; DOI: 10.1183/23120541.00332-2022 Published 20 March 2023