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“Lung volumes differentiate the predominance of emphysema versus airway disease phenotype in early COPD: an observational study of the COPDGene cohort”. Siyang Zeng, Gang Luo, David A. Lynch, Russell P. Bowler and Mehrdad Arjomandi. ERJ Open Res 2023; 9: 00289-2023

ERJ Open Research 2023 9: 50289-2023; DOI: 10.1183/23120541.50289-2023
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The originally published version of this article included an error in figure 5 that misrepresented the statistical comparison between data presented in parts a and b. The figure and its caption have been corrected in the article itself, and the corrected version is shown below.

FIGURE 5
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FIGURE 5

(See following page) Spirometric progression of smokers with preserved spirometry (COPD Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage 0) at 5-year follow-up visit (V2) stratified by lung volumes. a) Functional residual capacity (FRC)/total lung capacity (TLC), b) FRC and c) TLC. Bar plots show the distribution of COPD GOLD stage at 5-year follow-up visit with strata of baseline lung volumes. The lung volumes were adjusted for age, sex, height and weight. Horizontal bars indicate statistically significant comparisons of the percentages between the high-tertile group in each lung volume stratification with the low-tertile group within that stratification using one-way ANOVA with the Tukey–Kramer post hoc test. The symbols on the bars indicate statistically significant comparisons of the likelihood of progressing to the corresponding GOLD stages between the high tertiles of different lung volume stratifications using mixed-effect logistic modelling with adjustment for age, sex, height, weight, smoking status (current versus former) and smoking burden (pack-years). GOLD stage 4 was omitted at 5-year follow-up because no participants developed GOLD stage 4. PRISm: preserved ratio and impaired spirometry. * and #: p<0.001 between panels a and c.

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ERJ Open Research: 9 (5)
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“Lung volumes differentiate the predominance of emphysema versus airway disease phenotype in early COPD: an observational study of the COPDGene cohort”. Siyang Zeng, Gang Luo, David A. Lynch, Russell P. Bowler and Mehrdad Arjomandi. ERJ Open Res 2023; 9:…
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“Lung volumes differentiate the predominance of emphysema versus airway disease phenotype in early COPD: an observational study of the COPDGene cohort”. Siyang Zeng, Gang Luo, David A. Lynch, Russell P. Bowler and Mehrdad Arjomandi. ERJ Open Res 2023; 9: 00289-2023
ERJ Open Research Sep 2023, 9 (5) 50289-2023; DOI: 10.1183/23120541.50289-2023

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“Lung volumes differentiate the predominance of emphysema versus airway disease phenotype in early COPD: an observational study of the COPDGene cohort”. Siyang Zeng, Gang Luo, David A. Lynch, Russell P. Bowler and Mehrdad Arjomandi. ERJ Open Res 2023; 9: 00289-2023
ERJ Open Research Sep 2023, 9 (5) 50289-2023; DOI: 10.1183/23120541.50289-2023
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  • “Lung volume reduction in emphysema: a pragmatic prospective cohort study”. Christophe Dooms, Astrid Blondeel, Laurens J. Ceulemans, Johan Coolen, Stephanie Everaerts, Heleen Demeyer, Thierry Troosters Geert Verleden, Dirk Van Raemdonck and Wim Janssens. ERJ Open Res 2021; 7: 00877-2020
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