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The impact of the first COVID-19 surge on Severe Asthma Patients in the UK. Which is worse: The virus or the lockdown?

Steven J. Smith, John Busby, Liam G. Heaney, Paul E. Pfeffer, David J. Jackson, Freda Yang, Stephen J. Fowler, Andrew Menzies-Gow, Elfatih Idris, Thomas Brown, Robin Gore, Shoaib Faruqi, Paddy Dennison, James W. Dodd, Simon Doe, Adel H. Mansur, Radhika Priyadarshi, Joshua Holmes, Andrew Hearn, Hamsa Al-Aqqad, Lola Loewenthal, Angela Cooper, Lauren Fox, Mayurun Selvan, Michael G. Crooks, Alison Thompson, Daniel Higbee, Michelle Fawdon, Vishal Nathwani, LeanneJo Holmes, Rekha Chaudhuri on behalf of the UK Severe Asthma Registry
ERJ Open Research 2020; DOI: 10.1183/23120541.00768-2020
Steven J. Smith
1Gartnavel General Hospital and University of Glasgow, Glasgow, UK
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John Busby
2Queens University, Belfast, UK
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Liam G. Heaney
2Queens University, Belfast, UK
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Paul E. Pfeffer
3St Bartholomew's Hospital, Bart's Health NHS Trust, London & Queen Mary University of London, London, UK
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David J. Jackson
4Guys and St Thomas's Hospitals, London, UK
5Guy's and St Thomas’ NHS Trust, London & King's College London, London, UK
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  • ORCID record for David J. Jackson
Freda Yang
1Gartnavel General Hospital and University of Glasgow, Glasgow, UK
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Stephen J. Fowler
6School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester, UK
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Andrew Menzies-Gow
7Royal Brompton Hospital, London, UK
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Elfatih Idris
8Royal Stoke University Hospital, Stoke, UK
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Thomas Brown
9Queen Alexandra Hospital, Portsmouth, UK
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Robin Gore
10Addenbrooke's Hospital, Cambridge, UK
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Shoaib Faruqi
11Hull University Teaching Hospital, Hull, UK
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Paddy Dennison
12University Hospital Southampton, Southampton, UK
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James W. Dodd
13Academic respiratory unit, University of Bristol & North Bristol Lung Centre, Southmead Hospital, Bristol, UK
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Simon Doe
14Royal Victoria Infirmary, Newcastle, UK
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Adel H. Mansur
15Heartlands Hospital, University Hospitals Birmingham, Birmingham, UK
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Radhika Priyadarshi
3St Bartholomew's Hospital, Bart's Health NHS Trust, London & Queen Mary University of London, London, UK
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Joshua Holmes
2Queens University, Belfast, UK
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Andrew Hearn
4Guys and St Thomas's Hospitals, London, UK
5Guy's and St Thomas’ NHS Trust, London & King's College London, London, UK
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Hamsa Al-Aqqad
6School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester, UK
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Lola Loewenthal
7Royal Brompton Hospital, London, UK
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Angela Cooper
8Royal Stoke University Hospital, Stoke, UK
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Lauren Fox
9Queen Alexandra Hospital, Portsmouth, UK
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Mayurun Selvan
10Addenbrooke's Hospital, Cambridge, UK
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Michael G. Crooks
11Hull University Teaching Hospital, Hull, UK
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Alison Thompson
12University Hospital Southampton, Southampton, UK
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Daniel Higbee
13Academic respiratory unit, University of Bristol & North Bristol Lung Centre, Southmead Hospital, Bristol, UK
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Michelle Fawdon
14Royal Victoria Infirmary, Newcastle, UK
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Vishal Nathwani
15Heartlands Hospital, University Hospitals Birmingham, Birmingham, UK
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LeanneJo Holmes
6School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester, UK
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Rekha Chaudhuri
1Gartnavel General Hospital and University of Glasgow, Glasgow, UK
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Footnotes

This manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.

Conflict of interest: Dr. Smith has nothing to disclose.

Conflict of interest: Dr. Busby has nothing to disclose.

Conflict of interest: L.G. Heaney reports sponsorship for attending international scientific meetings from AstraZeneca, Boehringer Ingelheim, Chiesi, GSK and Napp Pharmaceutical; lecture fees and advisory boards fees from Novartis, Hoffman la Roche/Genentech Inc., Sanofi, GlaxoSmithKline, AstraZeneca, Evelo Biosciences, Teva, Theravance and Circassia; institutional grant funding from Medimmune, Novartis UK, Roche/Genentech Inc. and GlaxoSmithKline. He is Academic Lead for the Medical Research Council Stratified Medicine UK Consortium in Severe Asthma, which involves industrial partnerships with Amgen, Genentech/Hoffman la Roche, AstraZeneca, Medimmune, GlaxoSmithKline, Aerocrine and Vitalograph.

Conflict of interest: P.E. Pfeffer reports grants and travel fees from GlaxoSmithKline, and speaker and travel fees from AstraZeneca, outside the submitted work.

Conflict of interest: Dr. Jackson has nothing to disclose.

Conflict of interest: J.F. Yang reports speakers fees and travel support from AstraZeneca, and travel support from GlaxoSmithKline, outside the submitted work.

Conflict of interest: Dr. Fowler has nothing to disclose.

Conflict of interest: Dr. Menzies-Gow reports grants and personal fees from Astra Zeneca, personal fees from Glaxo SmithKline, personal fees from Sanofi, personal fees from Novartis, personal fees and non-financial support from Teva, personal fees from Vectura, outside the submitted work.

Conflict of interest: Dr. IDRIS has nothing to disclose.

Conflict of interest: T. Brown reports grants from Asthma UK and Innovate UK; personal fees and nonfinancial support from AstraZeneca, grants, speaker fees and travel expenses from GlaxoSmithKlines; speaker fees, advisory board fees, conference fees and travel expenses from Teva; conference fees and travel expenses from Napp Pharmaceuticals; and personal fees and nonfinancial support from Novartis, all outside the submitted work.

Conflict of interest: R. Gore reports speaker fees from GSK, Astra Zeneca and UK outside the submitted work.

Conflict of interest: Dr. Faruqi has nothing to disclose.

Conflict of interest: Dr. Dennison has nothing to disclose.

Conflict of interest: J.W. Dodd reports honoraria for educational meetings and expert advisory boards from Chiesi, AstraZeneca, Boehringer Ingelheim and GlaxoSmithKline; and registration, travel and accommodation for international conferences from Chiesi, outside the submitted work.

Conflict of interest: Dr. Doe has nothing to disclose.

Conflict of interest: A.H. Mansur reports personal and departmental fees for talks, advisory board, grants for service development, sponsorship to attend conferences from AstraZeneca, GSK, Novartis, Chiesi, Napp, Sanofi and Teva, outside the submitted work.

Conflict of interest: Dr. Priyadarshi has nothing to disclose.

Conflict of interest: Mr. Holmes has nothing to disclose.

Conflict of interest: Dr. Hearn has nothing to disclose.

Conflict of interest: Mrs. Al-Aqqad has nothing to disclose.

Conflict of interest: Lola Loewenthal

Conflict of interest: Dr. Cooper has nothing to disclose.

Conflict of interest: Lauren Fox has nothing to disclose.

Conflict of interest: Dr. Selvan has nothing to disclose.

Conflict of interest: Dr. Crooks has nothing to disclose.

Conflict of interest: Alison Thompson

Conflict of interest: Dr. Higbee has nothing to disclose.

Conflict of interest: Michelle Fawdon

Conflict of interest: Dr. Nathwani has nothing to disclose.

Conflict of interest: L. Holmes reports speaker fees from Novartis and AstraZeneca, and conference sponsorship from Teva, outside the submitted work.

Conflict of interest: R. Chaudhuri reports advisory board meetings, research grant, speaker fees and conference travel support from AstraZeneca, advisory board meeting and speaker fees from GSK, advisory board meeting fees and nonfinancial support from Teva, advisory board meeting and speaker fees from Novartis, advisory board meeting fees and nonfinancial support from Chiesi, and conference travel support from Napp Pharmaceuticals, outside the submitted work.

This is a PDF-only article. Please click on the PDF link above to read it.

  • Received October 22, 2020.
  • Copyright ©ERS 2020
http://creativecommons.org/licenses/by-nc/4.0/

This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.

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The impact of the first COVID-19 surge on Severe Asthma Patients in the UK. Which is worse: The virus or the lockdown?
Steven J. Smith, John Busby, Liam G. Heaney, Paul E. Pfeffer, David J. Jackson, Freda Yang, Stephen J. Fowler, Andrew Menzies-Gow, Elfatih Idris, Thomas Brown, Robin Gore, Shoaib Faruqi, Paddy Dennison, James W. Dodd, Simon Doe, Adel H. Mansur, Radhika Priyadarshi, Joshua Holmes, Andrew Hearn, Hamsa Al-Aqqad, Lola Loewenthal, Angela Cooper, Lauren Fox, Mayurun Selvan, Michael G. Crooks, Alison Thompson, Daniel Higbee, Michelle Fawdon, Vishal Nathwani, LeanneJo Holmes, Rekha Chaudhuri
ERJ Open Research Jan 2020, 00768-2020; DOI: 10.1183/23120541.00768-2020

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The impact of the first COVID-19 surge on Severe Asthma Patients in the UK. Which is worse: The virus or the lockdown?
Steven J. Smith, John Busby, Liam G. Heaney, Paul E. Pfeffer, David J. Jackson, Freda Yang, Stephen J. Fowler, Andrew Menzies-Gow, Elfatih Idris, Thomas Brown, Robin Gore, Shoaib Faruqi, Paddy Dennison, James W. Dodd, Simon Doe, Adel H. Mansur, Radhika Priyadarshi, Joshua Holmes, Andrew Hearn, Hamsa Al-Aqqad, Lola Loewenthal, Angela Cooper, Lauren Fox, Mayurun Selvan, Michael G. Crooks, Alison Thompson, Daniel Higbee, Michelle Fawdon, Vishal Nathwani, LeanneJo Holmes, Rekha Chaudhuri
ERJ Open Research Jan 2020, 00768-2020; DOI: 10.1183/23120541.00768-2020
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