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Heparin-binding protein levels correlated with aggravation and multi-organ damage in severe COVID-19

Mingshan Xue, Yifeng Zeng, Hui-Qi Qu, Teng Zhang, Ning Li, Huimin Huang, Peiyan Zheng, Haisheng Hu, Luqian Zhou, Zhifeng Duan, Yong Zhang, Wei Bao, Li-feng Tian, Hakon Hakonarson, Nanshan Zhong, Xiaohua Douglas Zhang, Baoqing Sun
ERJ Open Research 2020; DOI: 10.1183/23120541.00741-2020
Mingshan Xue
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
5Mingshan Xue, Yifeng Zeng and Hui-Qi Qu should be regard as co-first authors
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Yifeng Zeng
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
5Mingshan Xue, Yifeng Zeng and Hui-Qi Qu should be regard as co-first authors
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Hui-Qi Qu
2Arctic Therapeutics at University of Akureyri, Borgir, Akureyri, Iceland
5Mingshan Xue, Yifeng Zeng and Hui-Qi Qu should be regard as co-first authors
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Teng Zhang
3Faculty of Health Sciences, University of Macau, Taipa, Macau, China
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Ning Li
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Huimin Huang
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Peiyan Zheng
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Haisheng Hu
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Luqian Zhou
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Zhifeng Duan
2Arctic Therapeutics at University of Akureyri, Borgir, Akureyri, Iceland
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Yong Zhang
2Arctic Therapeutics at University of Akureyri, Borgir, Akureyri, Iceland
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Wei Bao
2Arctic Therapeutics at University of Akureyri, Borgir, Akureyri, Iceland
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Li-feng Tian
2Arctic Therapeutics at University of Akureyri, Borgir, Akureyri, Iceland
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Hakon Hakonarson
2Arctic Therapeutics at University of Akureyri, Borgir, Akureyri, Iceland
4Faculty of Medicine, University of Iceland, Reykjavik, Iceland
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Nanshan Zhong
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Xiaohua Douglas Zhang
3Faculty of Health Sciences, University of Macau, Taipa, Macau, China
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Baoqing Sun
1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Article Information

DOI 
https://doi.org/10.1183/23120541.00741-2020

Published By 
European Respiratory Society
Online ISSN 
2312-0541
History 
  • Received October 10, 2020
  • Accepted November 4, 2020
  • Published online November 19, 2020.

Article Versions

  • previous version (November 12, 2020 - 07:13).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright ©ERS 2020 This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.

Author Information

  1. Mingshan Xue1,5,
  2. Yifeng Zeng1,5,
  3. Hui-Qi Qu2,5,
  4. Teng Zhang3,
  5. Ning Li1,
  6. Huimin Huang1,
  7. Peiyan Zheng1,
  8. Haisheng Hu1,
  9. Luqian Zhou1,
  10. Zhifeng Duan2,
  11. Yong Zhang2,
  12. Wei Bao2,
  13. Li-feng Tian2,
  14. Hakon Hakonarson2,4,
  15. Nanshan Zhong1,
  16. Xiaohua Douglas Zhang3 and
  17. Baoqing Sun1
  1. 1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
  2. 2Arctic Therapeutics at University of Akureyri, Borgir, Akureyri, Iceland
  3. 3Faculty of Health Sciences, University of Macau, Taipa, Macau, China
  4. 4Faculty of Medicine, University of Iceland, Reykjavik, Iceland
  5. 5Mingshan Xue, Yifeng Zeng and Hui-Qi Qu should be regard as co-first authors
  1. Nanshan Zhong, MD and Baoqing Sun, MD, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China. E-mail: nanshan{at}vip.163.com; E-mail: sunbaoqing{at}vip.163.com; Xiaohua Douglas Zhang, PhD, Faculty of Health Sciences, University of Macau, Avenida da Universidade, Taipa, Macau, China. E-mail: douglaszhang{at}um.edu.mo
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Funding

  • Zhejiang University special scientific research fund for COVID-19 prevention and control

    2020XGZX001, 2020XGZX025
  • Guangdong Science and Technology Fund

    2020B1111300001

Article usage

Article usage: November 2020 to December 2020

AbstractFullPdf
Nov 202021132969
Dec 2020959025

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Heparin-binding protein levels correlated with aggravation and multi-organ damage in severe COVID-19
Mingshan Xue, Yifeng Zeng, Hui-Qi Qu, Teng Zhang, Ning Li, Huimin Huang, Peiyan Zheng, Haisheng Hu, Luqian Zhou, Zhifeng Duan, Yong Zhang, Wei Bao, Li-feng Tian, Hakon Hakonarson, Nanshan Zhong, Xiaohua Douglas Zhang, Baoqing Sun
ERJ Open Research Jan 2020, 00741-2020; DOI: 10.1183/23120541.00741-2020

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Heparin-binding protein levels correlated with aggravation and multi-organ damage in severe COVID-19
Mingshan Xue, Yifeng Zeng, Hui-Qi Qu, Teng Zhang, Ning Li, Huimin Huang, Peiyan Zheng, Haisheng Hu, Luqian Zhou, Zhifeng Duan, Yong Zhang, Wei Bao, Li-feng Tian, Hakon Hakonarson, Nanshan Zhong, Xiaohua Douglas Zhang, Baoqing Sun
ERJ Open Research Jan 2020, 00741-2020; DOI: 10.1183/23120541.00741-2020
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