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A ten year follow-up of key gas exchange exercise parameters in a general population – Results of the Study of Health in Pomerania

Beate Stubbe, Till Ittermann, Sabine Kaczmarek, Anne Obst, Martin Bahls, Tom Bollmann, Sven Gläser, Henry Völzke, Marcus Dörr, Ralf Ewert
ERJ Open Research 2020; DOI: 10.1183/23120541.00350-2020
Beate Stubbe
1Department of Internal Medicine B, Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, University Medicine Greifswald, Greifswald, Germany
5contributed equally
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  • ORCID record for Beate Stubbe
  • For correspondence: beate.stubbe@med.uni-greifswald.de
Till Ittermann
2Institute for Community Medicine, SHIP/Clinical-Epidemiological Research, University Greifswald, Greifswald, Germany
5contributed equally
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Sabine Kaczmarek
1Department of Internal Medicine B, Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, University Medicine Greifswald, Greifswald, Germany
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Anne Obst
1Department of Internal Medicine B, Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, University Medicine Greifswald, Greifswald, Germany
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Martin Bahls
1Department of Internal Medicine B, Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, University Medicine Greifswald, Greifswald, Germany
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Tom Bollmann
3Helios Hanse Hospital Stralsund, Stralsund, Germany
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Sven Gläser
4Vivantes Hospital Berlin-Neukölln, Berlin, Germany
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Henry Völzke
2Institute for Community Medicine, SHIP/Clinical-Epidemiological Research, University Greifswald, Greifswald, Germany
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Marcus Dörr
1Department of Internal Medicine B, Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, University Medicine Greifswald, Greifswald, Germany
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Ralf Ewert
1Department of Internal Medicine B, Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, University Medicine Greifswald, Greifswald, Germany
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Abstract

Background Cardiopulmonary exercise testing (CPET) is a frequently used method for the evaluation of the cardiorespiratory system. The prognostic relevance of the measured parameters is commonly known. Longitudinal data on cardiorespiratory fitness in a large sample of well characterised healthy volunteers are rare in literature.

Methods CPET data of 615 healthy individuals who voluntarily took part in the Study of Health in Pomerania (SHIP) at three times were analysed. The median observation time was 10.5 years. The age range was 25 to 85 years.

Results Over the observed timeframe and with rising age a decline in maximum power, oxygen uptake and oxygen uptake at the anaerobic threshold was detectable. This decline was aggravated with rising age. For the VÉ/VCO2 slope an increase in individuals older than 50 years was measured only.

Conclusion The present study affirms the decrease in aerobic capacity with increasing age in a selected, well characterised, healthy study sample, that seems to be less pronounced in women.

Footnotes

This manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.

Conflict of interest:

Conflict of interest:

Conflict of interest: Dr. Kaczmarek has nothing to disclose.

Conflict of interest: Dr. Obst has nothing to disclose.

Conflict of interest: Dr. Bahls has nothing to disclose.

Conflict of interest: Dr. Bollmann has nothing to disclose.

Conflict of interest: Dr. Gläser reports personal fees from Boehringer Ingelheim, grants and personal fees from Novartis Pharma, personal fees from Roche Pharma, personal fees from Berlin Chemie, personal fees from PneumRX, personal fees from PulmonX, personal fees from Actelion Pharma, personal fees from Bayer Heatlthcare, outside the submitted work;.

Conflict of interest: Dr. Völzke has nothing to disclose.

Conflict of interest: Dr. Dörr has nothing to disclose.

Conflict of interest: Dr. Ewert has nothing to disclose.

This is a PDF-only article. Please click on the PDF link above to read it.

  • Received June 4, 2020.
  • Accepted November 13, 2020.
  • Copyright ©ERS 2020
http://creativecommons.org/licenses/by-nc/4.0/

This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.

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A ten year follow-up of key gas exchange exercise parameters in a general population – Results of the Study of Health in Pomerania
Beate Stubbe, Till Ittermann, Sabine Kaczmarek, Anne Obst, Martin Bahls, Tom Bollmann, Sven Gläser, Henry Völzke, Marcus Dörr, Ralf Ewert
ERJ Open Research Jan 2020, 00350-2020; DOI: 10.1183/23120541.00350-2020

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A ten year follow-up of key gas exchange exercise parameters in a general population – Results of the Study of Health in Pomerania
Beate Stubbe, Till Ittermann, Sabine Kaczmarek, Anne Obst, Martin Bahls, Tom Bollmann, Sven Gläser, Henry Völzke, Marcus Dörr, Ralf Ewert
ERJ Open Research Jan 2020, 00350-2020; DOI: 10.1183/23120541.00350-2020
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