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Nasal upregulation of CST1 in dog sensitised children with severe allergic airway disease

Ulrika Käck, Elisabet Einarsdottir, Marianne van Hage, Anna Asarnoj, Anna James, Anna Nopp, Kaarel Krjutskov, Shintaro Katayama, Juha Kere, Gunnar Lilja, Cilla Söderhäll, Jon R. Konradsen
ERJ Open Research 2021; DOI: 10.1183/23120541.00917-2020
Ulrika Käck
1Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden
2Sachś Childrens and Youth Hospital, Södersjukhuset, Stockholm, Stockholm, Sweden
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Elisabet Einarsdottir
3Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
4Science for Life Laboratory, Department of Gene Technology, KTH-Royal Institute of Technology, Solna, Sweden
5Folkhälsan Research Center, Helsinki, Finland
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Marianne van Hage
6Department of Medicine Solna, Division of Immunology and Allergy, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
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Anna Asarnoj
7Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden
8Department of Womeńs and Children's Health, Karolinska Institutet, Stockholm, Sweden
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Anna James
9Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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Anna Nopp
1Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden
2Sachś Childrens and Youth Hospital, Södersjukhuset, Stockholm, Stockholm, Sweden
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Kaarel Krjutskov
3Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
10Department of Obstetrics and Gynecology, University of Tartu, Tartu, Estonia
11Competence Centre on Health Technologies, Tartu, Estonia
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Shintaro Katayama
3Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
5Folkhälsan Research Center, Helsinki, Finland
12University of Helsinki, Stem Cells and Metabolism Research Program, Helsinki, Finland
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  • ORCID record for Shintaro Katayama
Juha Kere
3Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
13Folkhälsan Research Institute, and Stem Cell and Metabolism Research Program, University of Helsinki, Helsinki, Finland
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Gunnar Lilja
1Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden
2Sachś Childrens and Youth Hospital, Södersjukhuset, Stockholm, Stockholm, Sweden
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Cilla Söderhäll
3Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
7Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden
8Department of Womeńs and Children's Health, Karolinska Institutet, Stockholm, Sweden
14shared last authorship
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  • For correspondence: cilla.soderhall@ki.se
Jon R. Konradsen
7Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden
8Department of Womeńs and Children's Health, Karolinska Institutet, Stockholm, Sweden
14shared last authorship
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Article Information

DOI 
https://doi.org/10.1183/23120541.00917-2020

Published By 
European Respiratory Society
Online ISSN 
2312-0541
History 
  • Received December 7, 2020
  • Accepted January 27, 2021
  • Published online February 18, 2021.

Copyright & Usage 
©The authors 2021 This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org

Author Information

  1. Ulrika Käck1,2,
  2. Elisabet Einarsdottir3,4,5,
  3. Marianne van Hage6,
  4. Anna Asarnoj7,8,
  5. Anna James9,
  6. Anna Nopp1,2,
  7. Kaarel Krjutskov3,10,11,
  8. Shintaro Katayama3,5,12,
  9. Juha Kere3,13,
  10. Gunnar Lilja1,2,
  11. Cilla Söderhäll3,7,8,14⇑ and
  12. Jon R. Konradsen7,8,14
  1. 1Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden
  2. 2Sachś Childrens and Youth Hospital, Södersjukhuset, Stockholm, Stockholm, Sweden
  3. 3Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
  4. 4Science for Life Laboratory, Department of Gene Technology, KTH-Royal Institute of Technology, Solna, Sweden
  5. 5Folkhälsan Research Center, Helsinki, Finland
  6. 6Department of Medicine Solna, Division of Immunology and Allergy, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
  7. 7Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden
  8. 8Department of Womeńs and Children's Health, Karolinska Institutet, Stockholm, Sweden
  9. 9Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
  10. 10Department of Obstetrics and Gynecology, University of Tartu, Tartu, Estonia
  11. 11Competence Centre on Health Technologies, Tartu, Estonia
  12. 12University of Helsinki, Stem Cells and Metabolism Research Program, Helsinki, Finland
  13. 13Folkhälsan Research Institute, and Stem Cell and Metabolism Research Program, University of Helsinki, Helsinki, Finland
  14. 14shared last authorship
  1. Cilla Söderhäll, Karolinska Institutet, Department of Women's and Children's health, BioClinicum J9:30, Visionsgatan 4, SE-171 76 Stockholm, Sweden. E-mail: cilla.soderhall{at}ki.se
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Funding

  • ChAMP (the Centre for Allergy Research Highlights Asthma Markers of Phenotype) consortium which is funded by the Karolinska Institutet, AstraZeneca & Science for Life Laboratory Joint Research Collaboration

    grant number 4-665/2013
  • Jane & Aatos Erkko Foundation

  • The Swedish Cancer and Allergy Foundation

  • the Swedish Association for Allergology

  • Vetenskapsrådet

  • Stiftelsen för Strategisk Forskning

    grant number RB13-0196
  • Hjärt-Lungfonden

  • Göran Gustafssons Stiftelse för Naturvetenskaplig och Medicinsk Forskning

  • Astma- och Allergiförbundet

  • Queen Silvia’s Jubilee Foundation

  • Region Stockholm (ALF-project)

  • Ellen, Walter and Lennart Hesselman Foundation for Scientific Research

  • Horizon 2020 Framework Programme

    (GA 810752)
  • Sigrid Juséliuksen Säätiö

Article usage

Article usage: February 2021 to March 2021

AbstractFullPdf
Feb 2021414320
Mar 2021504833

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Vol 7 Issue 2 Table of Contents
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Nasal upregulation of CST1 in dog sensitised children with severe allergic airway disease
Ulrika Käck, Elisabet Einarsdottir, Marianne van Hage, Anna Asarnoj, Anna James, Anna Nopp, Kaarel Krjutskov, Shintaro Katayama, Juha Kere, Gunnar Lilja, Cilla Söderhäll, Jon R. Konradsen
ERJ Open Research Jan 2021, 00917-2020; DOI: 10.1183/23120541.00917-2020

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Nasal upregulation of CST1 in dog sensitised children with severe allergic airway disease
Ulrika Käck, Elisabet Einarsdottir, Marianne van Hage, Anna Asarnoj, Anna James, Anna Nopp, Kaarel Krjutskov, Shintaro Katayama, Juha Kere, Gunnar Lilja, Cilla Söderhäll, Jon R. Konradsen
ERJ Open Research Jan 2021, 00917-2020; DOI: 10.1183/23120541.00917-2020
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