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Dyspnea and clinical outcome in critically ill patients receiving noninvasive support for COVID-19 respiratory failure: post-hoc analysis of a randomized clinical trial

Luca S. Menga, Domenico Luca Grieco, Tommaso Rosà, Melania Cesarano, Luca Delle Cese, Cecilia Berardi, Gabriele Pintaudi, Eloisa Sofia Tanzarella, Salvatore L. Cutuli, Gennaro De Pascale, Salvatore Maurizio Maggiore, Massimo Antonelli for the COVID-ICU Gemelli study group
ERJ Open Research 2021; DOI: 10.1183/23120541.00418-2021
Luca S. Menga
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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  • For correspondence: dlgrieco@outlook.it
Domenico Luca Grieco
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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  • ORCID record for Domenico Luca Grieco
Tommaso Rosà
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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Melania Cesarano
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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Luca Delle Cese
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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Cecilia Berardi
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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Gabriele Pintaudi
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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Eloisa Sofia Tanzarella
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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Salvatore L. Cutuli
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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Gennaro De Pascale
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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Salvatore Maurizio Maggiore
3University Department of Innovative Technologies in Medicine and Dentistry, Gabriele d”Annunzio University of Chieti-Pescara, Chieti, Italy
4Department of Anesthesiology, Critical Care Medicine and Emergency, SS. Annunziata Hospital, Chieti, Italy
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Massimo Antonelli
1Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
2Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore Rome, Italy
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Footnotes

This manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.

Conflict of interest: Dr. Menga has nothing to disclose.

Conflict of interest: Dr. Grieco reports non-financial support from Maquet, non-financial support from Air Liquide, grants from GE, outside the submitted work; .

Conflict of interest: Dr. Rosà has nothing to disclose.

Conflict of interest: Dr. Cesarano has nothing to disclose.

Conflict of interest: Dr. Delle Cese has nothing to disclose.

Conflict of interest: Dr. Berardi has nothing to disclose.

Conflict of interest: Dr. Pintaudi has nothing to disclose.

Conflict of interest: Dr. Tanzarella has nothing to disclose.

Conflict of interest: Dr. Cutuli has nothing to disclose.

Conflict of interest: Dr. De Pascale has nothing to disclose.

Conflict of interest: Dr. Maggiore reports grants from Fisher and Paykel Healthcare, personal fees from Dreger Medical, personal fees from GE Healthcare, outside the submitted work; .

Conflict of interest: Dr. Antonelli reports grants from GE, grants from Toray, personal fees from Maquet, outside the submitted work; .

This is a PDF-only article. Please click on the PDF link above to read it.

  • Received July 10, 2021.
  • Accepted July 15, 2021.
  • Copyright ©The authors 2021
http://creativecommons.org/licenses/by-nc/4.0/

This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions{at}ersnet.org

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Dyspnea and clinical outcome in critically ill patients receiving noninvasive support for COVID-19 respiratory failure: post-hoc analysis of a randomized clinical trial
Luca S. Menga, Domenico Luca Grieco, Tommaso Rosà, Melania Cesarano, Luca Delle Cese, Cecilia Berardi, Gabriele Pintaudi, Eloisa Sofia Tanzarella, Salvatore L. Cutuli, Gennaro De Pascale, Salvatore Maurizio Maggiore, Massimo Antonelli
ERJ Open Research Jan 2021, 00418-2021; DOI: 10.1183/23120541.00418-2021

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Dyspnea and clinical outcome in critically ill patients receiving noninvasive support for COVID-19 respiratory failure: post-hoc analysis of a randomized clinical trial
Luca S. Menga, Domenico Luca Grieco, Tommaso Rosà, Melania Cesarano, Luca Delle Cese, Cecilia Berardi, Gabriele Pintaudi, Eloisa Sofia Tanzarella, Salvatore L. Cutuli, Gennaro De Pascale, Salvatore Maurizio Maggiore, Massimo Antonelli
ERJ Open Research Jan 2021, 00418-2021; DOI: 10.1183/23120541.00418-2021
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