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AV-101, a Novel Inhaled Dry Powder Formulation of Imatinib, in Healthy Adult Participants: A Phase 1 Single and Multiple Ascending Dose Study

Hunter Gillies, Ralph Niven, Benjamin T. Dake, Murali M. Chakinala, Jeremy P. Feldman, Nicholas S. Hill, Marius M. Hoeper, Marc Humbert, Vallerie V. McLaughlin, Martin Kankam
ERJ Open Research 2022; DOI: 10.1183/23120541.00433-2022
Hunter Gillies
1Aerovate Therapeutics, Waltham, MA, USA
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  • For correspondence: hgillies@aerovatetx.com
Ralph Niven
1Aerovate Therapeutics, Waltham, MA, USA
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Benjamin T. Dake
1Aerovate Therapeutics, Waltham, MA, USA
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Murali M. Chakinala
2Washington University School of Medicine, St. Louis, MO, USA
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Jeremy P. Feldman
3Arizona Pulmonary Specialists, Phoenix, AZ, USA
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Nicholas S. Hill
4Pulmonary Critical Care & Sleep Division, Tufts Medical Center, Boston, MA, USA
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Marius M. Hoeper
5Respiratory Medicine, Hannover Medical School and German Centre of Lung Research, Hannover, Germany
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  • ORCID record for Marius M. Hoeper
Marc Humbert
6Université Paris–Saclay, INSERM, Assistance Publique Hôpitaux de Paris, Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital Bicêtre, Le Kremlin Bicêtre, France
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Vallerie V. McLaughlin
7University of Michigan, Ann Arbor, MI, USA
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Martin Kankam
8Altasciences Clinical Kansas, Inc., Overland Park, KS, USA
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Article Information

DOI 
https://doi.org/10.1183/23120541.00433-2022

Published By 
European Respiratory Society
Online ISSN 
2312-0541
History 
  • Received August 26, 2022
  • Accepted October 16, 2022
  • Published online November 10, 2022.

Copyright & Usage 
Copyright ©The authors 2022 This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org

Author Information

  1. Hunter Gillies1⇑,
  2. Ralph Niven1,
  3. Benjamin T. Dake1,
  4. Murali M. Chakinala2,
  5. Jeremy P. Feldman3,
  6. Nicholas S. Hill4,
  7. Marius M. Hoeper5,
  8. Marc Humbert6,
  9. Vallerie V. McLaughlin7 and
  10. Martin Kankam8
  1. 1Aerovate Therapeutics, Waltham, MA, USA
  2. 2Washington University School of Medicine, St. Louis, MO, USA
  3. 3Arizona Pulmonary Specialists, Phoenix, AZ, USA
  4. 4Pulmonary Critical Care & Sleep Division, Tufts Medical Center, Boston, MA, USA
  5. 5Respiratory Medicine, Hannover Medical School and German Centre of Lung Research, Hannover, Germany
  6. 6Université Paris–Saclay, INSERM, Assistance Publique Hôpitaux de Paris, Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital Bicêtre, Le Kremlin Bicêtre, France
  7. 7University of Michigan, Ann Arbor, MI, USA
  8. 8Altasciences Clinical Kansas, Inc., Overland Park, KS, USA
  1. Corresponding author: Hunter Gillies (hgillies{at}aerovatetx.com)
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Funding

  • Aerovate Therapeutics

Article usage

Article usage: November 2022 to December 2022

AbstractFullPdf
Nov 202278499160
Dec 20222610453

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ERJ Open Research: 9 (1)
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AV-101, a Novel Inhaled Dry Powder Formulation of Imatinib, in Healthy Adult Participants: A Phase 1 Single and Multiple Ascending Dose Study
Hunter Gillies, Ralph Niven, Benjamin T. Dake, Murali M. Chakinala, Jeremy P. Feldman, Nicholas S. Hill, Marius M. Hoeper, Marc Humbert, Vallerie V. McLaughlin, Martin Kankam
ERJ Open Research Jan 2022, 00433-2022; DOI: 10.1183/23120541.00433-2022

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AV-101, a Novel Inhaled Dry Powder Formulation of Imatinib, in Healthy Adult Participants: A Phase 1 Single and Multiple Ascending Dose Study
Hunter Gillies, Ralph Niven, Benjamin T. Dake, Murali M. Chakinala, Jeremy P. Feldman, Nicholas S. Hill, Marius M. Hoeper, Marc Humbert, Vallerie V. McLaughlin, Martin Kankam
ERJ Open Research Jan 2022, 00433-2022; DOI: 10.1183/23120541.00433-2022
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