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Distinct profiles of host responses between plasma and lower respiratory tract during acute respiratory failure

Georgios D. Kitsios, Seyed Mehdi Nouraie, Shulin Qin, Yingze Zhang, Prabir Ray, Anuradha Ray, Janet S. Lee, Alison Morris, Bryan J. McVerry, William Bain
ERJ Open Research 2023; DOI: 10.1183/23120541.00743-2022
Georgios D. Kitsios
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
2Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA
3Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, PA, USA
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  • For correspondence: kitsiosg@upmc.edu
Seyed Mehdi Nouraie
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
2Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA
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Shulin Qin
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
3Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, PA, USA
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Yingze Zhang
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
2Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA
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Prabir Ray
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
2Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA
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Anuradha Ray
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
2Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA
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Janet S. Lee
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
2Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA
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Alison Morris
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
2Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA
3Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, PA, USA
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Bryan J. McVerry
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
2Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA
3Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, PA, USA
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William Bain
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
2Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA
4Veteran's Affairs Pittsburgh Healthcare System, Pittsburgh, PA, USA
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Footnotes

This manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.

Conflict of Interest: Dr. Kitsios has received research funding from Karius, Inc. Dr. McVerry has received research funding from Bayer Pharmaceuticals, Inc, consulting fees from Boehringer Inhelheim, BioAegis, Synairgen, and payments from expert testimony from VeraMedica, LLC.

Conflict of interest: The other authors have no conflicts of interest to disclose.

This is a PDF-only article. Please click on the PDF link above to read it.

  • Copyright ©The authors 2023
http://creativecommons.org/licenses/by-nc/4.0/

This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions{at}ersnet.org

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Distinct profiles of host responses between plasma and lower respiratory tract during acute respiratory failure
Georgios D. Kitsios, Seyed Mehdi Nouraie, Shulin Qin, Yingze Zhang, Prabir Ray, Anuradha Ray, Janet S. Lee, Alison Morris, Bryan J. McVerry, William Bain
ERJ Open Research Jan 2023, 00743-2022; DOI: 10.1183/23120541.00743-2022

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Distinct profiles of host responses between plasma and lower respiratory tract during acute respiratory failure
Georgios D. Kitsios, Seyed Mehdi Nouraie, Shulin Qin, Yingze Zhang, Prabir Ray, Anuradha Ray, Janet S. Lee, Alison Morris, Bryan J. McVerry, William Bain
ERJ Open Research Jan 2023, 00743-2022; DOI: 10.1183/23120541.00743-2022
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