Abstract
Background Chronic cough (CC) is underevaluated and underevaluated. The availability of a tool easy to complete, score, and interpret and with the psychometric properties requested for use in individual patients could improve clinical practice.
Objective This cross-sectional study aimed to validate the Chronic Cough Patient Perspective (CCPP) for assessing CC in daily practice.
Methods A provisional CCPP was created by iteratively reducing the Chronic Cough Impact Questionnaire (CCIQ). Its psychometric properties were tested in CC patients at baseline (visit 1) and after 1 month (visit 2).
Results The reduction process yielded an 8-item provisional version, subsequently validated in 150 patients (36.33% males, mean age 50±16.9 years). Exploratory factor analysis revealed a one-dimensional structure, with one item being deleted as it did not align with the extracted dimension. The 7-item version of the CCPP showed a strong correlation with the CCIQ (r=0.902 at visit 1, r=0.932 at visit 2) and internal consistency (Cronbach's alpha values: 0.85 at visit 1, 0.93 at visit 2); discriminant and convergent validity were satisfactory. The reliability, assessed in 21 patients with no change in CC (Global Rating Scale=0), was high (concordance correlation coefficient=0.815; interclass coefficient=0.823). A score ≤5 indicates optimalHealth Related Quality of Life (HRQoL) attainment, with a minimum important difference of 3. The mean CCPP score was 20.5 (±6.24) at enrolment, and only 37.33% of the participants achieved an optimal HRQoL at visit 2.
Conclusion The CCPP exhibited good psychometric properties suitable for clinical use, providing a valid, reliable, and standardised assessment of CC's impact on HRQoL.
Footnotes
This manuscript has recently been accepted for publication in the ERJ Open Research. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJOR online. Please open or download the PDF to view this article.
Conflict of interest: The Authors have no conflict of interest to declare.
This is a PDF-only article. Please click on the PDF link above to read it.
- Received March 22, 2024.
- Accepted July 31, 2024.
- Copyright ©The authors 2024
This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions{at}ersnet.org
