ERJOR Early View

February 25, 2021

Research letter
Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
Merel Jacobs, Lies Lahousse, Hannelore P. Van Eeckhoutte, Sara R.A. Wijnant, Joris R. Delanghe, Guy G. Brusselle, Ken R. Bracke

ERJ Open Research; DOI: 10.1183/23120541.00940-2020
Original article
Microbial and clinical factors are related to recurrence of symptoms after childhood lower respiratory tract infection
Emma M. de Koff, Wing Ho Man, Marlies A. van Houten, Arine M. Vlieger, Mei Ling J.N. Chu, Elisabeth A.M. Sanders, Debby Bogaert

ERJ Open Research; DOI: 10.1183/23120541.00939-2020

February 18, 2021

Research letter
Detection of C. acnes in granulomas of patients with either hypersensitivity pneumonitis or vasculitis reveals that its presence is not unique for sarcoidosis
Els Beijer, Kees Seldenrijk, Bob Meek, Jan Damen, Marian J. R. Quanjel, Jan C. Grutters, Marcel Veltkamp

ERJ Open Research; DOI: 10.1183/23120541.00930-2020
Research letter
Analysis of pathological changes of the epithelium in the COVID-19 patient airways
Wenguang Yin, Weitao Cao, Guangde Zhou, Lifei Wang, Jing Sun, Airu Zhu, Zhongfang Wang, Yumin Zhou, Xiaoqing Liu, Yimin Li, Nanshang Zhong, Jincun Zhao, Lei Liu, Pixin Ran

ERJ Open Research; DOI: 10.1183/23120541.00690-2020
Original article
Participation in physical activity is associated with reduced nocturnal hypoxaemia in males
David Stevens, Sarah Appleton, Yohannes Melaku, Sean Martin, Robert Adams, Gary Wittert on behalf of the MAILES investigators

ERJ Open Research; DOI: 10.1183/23120541.00852-2020
Research letter
Time on therapy and concomitant medication use of mepolizumab in Canada: A retrospective cohort study
J.K. Lee, A. Gendron, M. Knutson, N. Sriskandarajah, L. Mbuagbaw, S.G. Noorduyn

ERJ Open Research; DOI: 10.1183/23120541.00778-2020
Original article
Anti-HSP47 siRNA Lipid Nanoparticle ND-L02-s0201 Reverses Interstitial Pulmonary Fibrosis in Preclinical Rat Models
Yun Liu, Jian Liu, Alistair Quimbo, Fengcheng Xia, Jiping Yao, Jean-Pierre Clamme, Sonya Zabludoff, Jun Zhang, Wenbin Ying

ERJ Open Research; DOI: 10.1183/23120541.00733-2020
Original article
Critical care outcomes in patients with pre-existing pulmonary hypertension: insights from the ASPIRE registry
K. Bauchmuller, R. Condliffe, J. Southern, C. Billings, A. Charalampopoulos, C. A. Elliot, A. Hameed, D. G. Kiely, I. Sabroe, A. A. R. Thompson, A. Raithatha, G. H. Mills

ERJ Open Research; DOI: 10.1183/23120541.00046-2021
Original article
Sleep apnoea and incident malignancy in type 2 diabetes
Sarah Driendl, Michael Arzt, Claudia S. Zimmermann, Bettina Jung, Tobias Pukrop, Carsten A. Böger, Sebastian Haferkamp, Florian Zeman, Iris M. Heid, Stefan Stadler

ERJ Open Research; DOI: 10.1183/23120541.00036-2021
Original article
REINVENT: International Survey on REstrictive thoracic diseases IN long term home noninvasive VENTilation
P. Pierucci, C. Crimi, A. Carlucci, G.E. Carpagnano, J.P Janssens, M. Lujan, A. Noto, P. J. Wijkstra, W. Windisch, R. Scala

ERJ Open Research; DOI: 10.1183/23120541.00911-2020
Original article
Chest computed tomography and alveolar-arterial oxygen gradient as rapid tools to diagnose and triage mildly symptomatic COVID-19 pneumonia patients
Marlise P. de Roos, Iris D. Kilsdonk, Pieter-Paul W. Hekking, Jan Peringa, Nynke G. Dijkstra, Peter W.A. Kunst, Paul Bresser, Herre J. Reesink

ERJ Open Research; DOI: 10.1183/23120541.00737-2020
Original article
Comparison of inhalation technique with the Diskus® and Autohaler® in asthmatic children at home
A. van der Kolk, N. Lammers, M. Brusse-Keizer, J. van der Palen, J. Faber, R. Spenkelink-Visser, B.J. Thio

ERJ Open Research; DOI: 10.1183/23120541.00215-2019
Original article
Airflow limitation and tongue microbiota in community-dwelling elderly individuals
Toru Takeshita, Koichiro Matsumoto, Michiko Furuta, Satoru Fukuyama, Kenji Takeuchi, Hiroaki Ogata, Mikari Asakawa, Shinya Kageyama, Jun Hata, Toshiharu Ninomiya, Hiromasa Inoue, Yoshihisa Yamashita

ERJ Open Research; DOI: 10.1183/23120541.00616-2020
Original article
Pulmonary Hypertension in Eosinophilic Versus Non-Eosinophilic COPD
Bashar N. Alzghoul, Mohammad As Sayaideh, Brian F. Moreno, Saminder K. Singh, Ayoub Innabi, Raju Reddy, Eric S. Papierniak, Hassan M Alnuaimat

ERJ Open Research; DOI: 10.1183/23120541.00772-2020
Original article
Nasal upregulation of CST1 in dog sensitised children with severe allergic airway disease
Ulrika Käck, Elisabet Einarsdottir, Marianne van Hage, Anna Asarnoj, Anna James, Anna Nopp, Kaarel Krjutskov, Shintaro Katayama, Juha Kere, Gunnar Lilja, Cilla Söderhäll, Jon R. Konradsen

ERJ Open Research; DOI: 10.1183/23120541.00917-2020
Original article
Cystic fibrosis airway microbiota associated with outcomes of nontuberculous mycobacterial infection
Lindsay J. Caverly, Madsen Zimbric, Michelle Azar, Kristopher Opron, John J. LiPuma

ERJ Open Research; DOI: 10.1183/23120541.00578-2020
Original article
Treatable traits in an English cohort: Prevalence and predictors of future decline in lung function and quality of life in COPD
Muhammad Rehan Sarwar, Vanessa Marie McDonald, Michael John Abramson, Eldho Paul, Johnson George

ERJ Open Research; DOI: 10.1183/23120541.00934-2020
Original article
Effect of fexofenadine hydrochloride on allergic rhinitis aggravated by air pollutants
Anne K. Ellis, Margarita Murrieta-Aguttes, Sandy Furey, Pascaline Picard, Christopher Carlsten

ERJ Open Research; DOI: 10.1183/23120541.00806-2020

February 04, 2021

Research letter
A new KIF5B-ERBB4 gene fusion in a lung adenocarcinoma patient
Edouard Guenzi, Johan Pluvy, Alice Guyard, Marina Nguenang, Khedidja Rebah, Zoubida Benrahmoune, Jérome Lamoril, Aurelie Cazes, Valérie Gounant, Solenn Brosseau, Catherine Boileau, Gérard Zalcman, Nathalie Theou-Anton

ERJ Open Research; DOI: 10.1183/23120541.00582-2020
Original article
Prognostic value of right atrial dilation in patients with pulmonary embolism
Markus H. Lerchbaumer, Matthias Ebner, Christian O. Ritter, Laura Steimke, Nina I.J. Rogge, Carmen Sentler, Aaron Thielmann, Lukas Hobohm, Karsten Keller, Joachim Lotz, Gerd Hasenfuß, Rolf Wachter, Bernd Hamm, Stavros V. Konstantinides, Galit Aviram, Mareike Lankeit

ERJ Open Research; DOI: 10.1183/23120541.00414-2020
Original article
Self-Proning in COVID-19 Patients on Low-Flow Oxygen Therapy. A Cluster Randomised Controlled Trial
Aileen Kharat, Elise Dupuis-Lozeron, Chloé Cantero, Christophe Marti, Olivier Grosgurin, Sanaz Lolachi, Frédéric Lador, Jérôme Plojoux, Jean-Paul Janssens, Paola M. Soccal, Dan Adler

ERJ Open Research; DOI: 10.1183/23120541.00692-2020
Original article
Pulmonary hemodynamic response to exercise in highlanders versus lowlanders
S. Ulrich, S. Saxer, M. Furian, P.R. Bader, P. Appenzeller, P.M. Scheiwiller, M. Mademilov, U. Sheraliev, F. Tanner, T.M. Sooronbaev, K.E. Bloch, M. Lichtblau

ERJ Open Research; DOI: 10.1183/23120541.00937-2020
Review
Non-tuberculous mycobacteria pulmonary disease: an integrated approach beyond antibiotics
Paola Faverio, Federica De Giacomi, Bruno Dino Bodini, Anna Stainer, Alessia Fumagalli, Francesco Bini, Fabrizio Luppi, Stefano Aliberti

ERJ Open Research; DOI: 10.1183/23120541.00574-2020
Study protocol
Integrating Comprehensive Geriatric Assessment for people with COPD and frailty starting pulmonary rehabilitation: the Breathe Plus feasibility trial protocol
Lisa Jane Brighton, Catherine J Evans, Morag Farquhar, Katherine Bristowe, Aleksandra Kata, Jade Higman, Margaret Ogden, Claire Nolan, Deokhee Yi, Wei Gao, Maria Koulopoulou, Sharmeen Hasan, Claire Steves, William DC Man, Matthew Maddocks

ERJ Open Research; DOI: 10.1183/23120541.00717-2020
Invited review
ERS International Congress 2020: Highlights from the Thoracic Surgery and Transplantation Assembly
Dorina Esendagli, Unmil Shah, Guntug Batihan, Dimitrios Magouliotis, Federica Meloni, Robin Vos, Stefano Elia, Merel Hellemons

ERJ Open Research; DOI: 10.1183/23120541.00743-2020
Study protocol
BronchUK: Protocol for an observational cohort study and biobank in bronchiectasis
Anthony De Soyza, Philip Mawson, Adam T. Hill, Stuart Elborn, Judy M. Bradley, Charles S. Haworth, R. Andres Floto, Robert Wilson, Michael R. Loebinger, Mary Carroll, Megan Crichton, James D. Chalmers, Anita Sullivan, Jeremy Brown, John R. Hurst, Jamie Duckers, Martin Kelly, John Steer, Tim Gatheral, Paul P. Walker, Craig Winstanley, Alistair McGuire, David Denning, Richard McNally

ERJ Open Research; DOI: 10.1183/23120541.00775-2020

January 28, 2021

Original article
Conservative management of Covid 19 associated hypoxemia
Thomas Voshaar, Patrick Stais, Dieter Köhler, Dominic Dellweg

ERJ Open Research; DOI: 10.1183/23120541.00026-2021
Research letter
Increased blood Angiotensin Converting Enzyme 2 activity in critically ill COVID-19 patients
Dirk van Lier, Matthijs Kox, Karine Santos, Hans van der Hoeven, Janesh Pillay, Peter Pickkers

ERJ Open Research; DOI: 10.1183/23120541.00848-2020
Research letter
Thrombolysis for massive pulmonary embolisms in morbid obesity: a multi-site case control study
Chinthaka B Samaranayake, Gregory Keir, Colm McCabe, James Anderson, Khoa Tran, John W Upham

ERJ Open Research; DOI: 10.1183/23120541.00762-2020
Original article
“It's like being on a roller coaster”: The burden of caring for people with severe asthma
Eleanor C. Majellano, Vanessa L. Clark, Juliet M. Foster, Peter G. Gibson, Vanessa M. Mcdonald

ERJ Open Research; DOI: 10.1183/23120541.00812-2020
Original article
Chest physiotherapy enhances detection of Pseudomonas aeruginosa in non-expectorating CF children
Christophe Marguet, Véronique Houdouin, I. Pin, Philippe Reix, Frédéric Huet, Marie Mittaine, Sophie Ramel, Nathalie Wizla-Derambure, Michel Abely, Marie-Laure Dalphin, Michael Fayon, Tiphaine Bihouée, Muriel Le Bourgeois, Eric Deneuville, Harriet Corvol, Muriel Laurans, Laure Couderc, Evelyne Leroux, Ludovic Lémée

ERJ Open Research; DOI: 10.1183/23120541.00513-2020
Original article
Evaluation of a multicomponent grading system (Baveno classification) for obstructive sleep apnoea
Winfried J. Randerath, Simon Herkenrath, Marcel Treml, Ludger Grote, Jan Hedner, Maria Rosaria Bonsignore, Jean Louis Pépin, Silke Ryan, Sophia Schiza, Johan Verbraecken, Walter T. McNicholas, Athanasia Pataka, Pawel Sliwinski, Özen K. Basoglu

ERJ Open Research; DOI: 10.1183/23120541.00928-2020
Research letter
Home parasternal electromyography tracks patient-reported and physiological measures of recovery from severe COPD exacerbation
Rebecca Francesca D'Cruz, Eui-Sik Suh, Georgios Kaltsakas, Amy Dewar, Neeraj Mukesh Shah, Rita Priori, Abdel Douiri, Louise Rose, Nicholas Hart, Patrick Brian Murphy

ERJ Open Research; DOI: 10.1183/23120541.00709-2020
Research letter
Proteomic profiling of peripheral blood and bronchoalveolar lavage fluid in interstitial lung diseases: An explorative study
Sebastian Majewski, Xing Wu Zhou, Joanna Miłkowska-Dymanowska, Adam Białas, Wojciech Piotrowski, Andrei Malinovschi

ERJ Open Research; DOI: 10.1183/23120541.00489-2020
Invited review
ERS International Congress, 2020: highlights from the Epidemiology and Environment Assembly
Diana A van der Plaat, Aino K Rantala, Sheikh M Alif, Dilek Karadoğan, Yutong Cai, Orianne Dumas

ERJ Open Research; DOI: 10.1183/23120541.00849-2020
Original article
Prognostic value of clinically important deterioration in COPD: IMPACT trial analysis
MeiLan K Han, Gerard J Criner, Mark T Dransfield, David MG Halpin, Christine E Jones, Sally Kilbride, Peter Lange, Sally Lettis, David A Lipson, David A Lomas, Neil Martin, Fernando J Martinez, Robert A Wise, Ian P Naya, Dave Singh

ERJ Open Research; DOI: 10.1183/23120541.00663-2020

January 21, 2021

Original article
The economics of precision health: preventing air pollution-induced exacerbation in asthma
Tima Mohammadi, Mohsen Sadatsafavi, Chris Carlsten

ERJ Open Research; DOI: 10.1183/23120541.00790-2020
Original article
Is Laryngeal Hypersensitivity the Basis for Unexplained or Refractory Chronic Cough?
Krishna M. Sundar, Amanda Carole Stark, Nan Hu, Julie Barkmeier-Kraemer

ERJ Open Research; DOI: 10.1183/23120541.00793-2020
Review
The safety of cardio-selective beta1-blockers in asthma: literature review and search of global pharmacovigilance safety reports
Miriam Bennett, Catherina L Chang, Michael Tatley, Ruth Savage, Robert J Hancox

ERJ Open Research; DOI: 10.1183/23120541.00801-2020
Original article
Dyspnoea and Symptom Burden in Mild-Moderate COPD: the Canadian Cohort Obstructive Lung Disease Study
Mathew Cherian, Dennis Jensen, Wan C. Tan, Sara Mursleen, Emma C. Goodall, Gilbert A. Nadeau, Amnah M. Awan, Darcy D. Marciniuk, Brandie L. Walker, Shawn D. Aaron, Denis E. O'Donnell, Kenneth R. Chapman, François Maltais, Paul Hernandez, Don D. Sin, Andrea Benedetti, Jean Bourbeau

ERJ Open Research; DOI: 10.1183/23120541.00960-2020
Research letter
The effect of physical activity on asthma incidence over 10 years: population-based study
Anne Melissa Russell, Shyamali Dharmage, Elaine Fuertes, Alessandro Marcon, Anne-Elie Carsin, Silvia Pascual Erquicia, Joachim Heinrich, Ane Johannessen, Michael J Abramson, Andre F.S. Amaral, Isa Cerveri, Pascal Demoly, Vanessa Garcia-Larsen, Deborah Jarvis, Jesus Martinez-Moratalla, Dennis Nowak, Leopoldo Palacios-Gomez, Giulia Squillacioti, Wasif Raza, Margareta Emtner, Judith Garcia-Aymerich

ERJ Open Research; DOI: 10.1183/23120541.00970-2020
Original article
Esophageal pressure as a surrogate of pleural pressure in mechanically-ventilated patients
Antoine Tilmont, Benjamin Coiffard, Takeshi Yoshida, Florence Daviet, Karine Baumstarck, Geoffrey Brioude, Sami Hraiech, Jean-Marie Forel, Antoine Roch, Laurent Brochard, Laurent Papazian, Christophe Guervilly

ERJ Open Research; DOI: 10.1183/23120541.00646-2020
Original article
Central airway and peripheral lung structures in airway disease dominant COPD
Naoya Tanabe, Kaoruko Shimizu, Kunihiko Terada, Susumu Sato, Masaru Suzuki, Hiroshi Shima, Akira Oguma, Tsuyoshi Oguma, Satoshi Konno, Masaharu Nishimura, Toyohiro Hirai

ERJ Open Research; DOI: 10.1183/23120541.00672-2020
Original article
Diaphragmatic motion recorded by M-mode ultrasonography: limits of normality
Alain Boussuges, Julie Finance, Guillaume Chaumet, Fabienne Brégeon

ERJ Open Research; DOI: 10.1183/23120541.00714-2020
Research letter
Influence of ventilation inhomogeneity on diffusing capacity of carbon monoxide in smokers without chronic obstructive pulmonary disease
Johanna Manuela Kurz, Jeannette Frey, Reto Auer, Nicolas Rodondi, Sylvia Nyilas, Nikolay Pavlov, Manuela Funke-Chambour, Florian Singer

ERJ Open Research; DOI: 10.1183/23120541.00706-2020
Invited review
Respiratory Care in Myotubular Myopathy
Hui-leng Tan, Elaine Chan

ERJ Open Research; DOI: 10.1183/23120541.00641-2020
Original article
Early oseltamivir treatment improves survival in critically ill patients with influenza pneumonia
Gerard Moreno, Alejandro Rodríguez, Jordi Sole-Violán, Ignacio Martín-Loeches, Emili Díaz, María Bodí, Luis F. Reyes, Josep Gómez, Juan Guardiola, Sandra Trefler, Loreto Vidaur, Elisabet Papiol, Lorenzo Socias, Carolina García-Vidal, Eudald Correig, Judith Marín-Corral, Marcos I. Restrepo, Jonathan S. Nguyen-Van-Tam, Antoni Torres on behalf of the GETGAG Working Group

ERJ Open Research; DOI: 10.1183/23120541.00888-2020
Original article
Prevalence and Characteristics of Self-Reported Hypothyroidism and its Association with Non-Organ Specific Manifestations in US Sarcoidosis Patients: A Nationwide Registry Study
Bashar N. Alzghoul, Farah N. Amer, Diana Barb, Ayoub Innabi, Mamoun T. Mardini, Chen Bai, Bara Alzghoul, Tamara Al-Hakim, Noopur Singh, Mindy Buchanan, Leslie Serchuck, Diana Gomez Manjarres, Whitney W. Woodmansee, Lisa A. Maier, Divya C. Patel

ERJ Open Research; DOI: 10.1183/23120541.00754-2020
Original article
Predicting mortality during long-term follow-up in pulmonary arterial hypertension
David Kylhammar, Clara Hjalmarsson, Roger Hesselstrand, Kjell Jansson, Mohammad Kavianipour, Barbro Kjellström, Magnus Nisell, Stefan Söderberg, Göran Rådegran on behalf of the Swedish Association for Pulmonary Hypertension (SveFPH) and the Swedish Pulmonary Arterial Hypertension Registry (SPAHR)

ERJ Open Research; DOI: 10.1183/23120541.00837-2020
Study protocol
A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol
Matthew Northgraves, Judith Cohen, Victoria Allgar, David Currow, Simon Hart, Kelly Hird, Andrew Hodge, Miriam Johnson, Suzanne Mason, Flavia Swan, Ann Hutchinson

ERJ Open Research; DOI: 10.1183/23120541.00955-2020

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January 28, 2021

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