ERJOR Early View

September 16, 2021

Research letter
Short-term effects of menthol on walking dyspnea in patients with COPD: a randomised, single blinded, cross-over study
Guillaume Prieur, Marc Beaumont, Mathieu Delorme, Yann Combret, Clement Medrinal, Roger Hilfiker, Tristan Bonnevie, Francis-Edouard Gravier, Pauline Smondack, Bouchra Lamia, Gregory Reychler

ERJ Open Research; DOI: 10.1183/23120541.00450-2021
Original research article
Is asthma associated with COVID-19 infection? A UK Biobank analysis
Caroline J. Lodge, Alice Doherty, Dinh Bui, Raisa Cassim, Adrian J. Lowe, Alvar Agusti, Melissa A. Russell, Shyamali C. Dharmage

ERJ Open Research; DOI: 10.1183/23120541.00309-2021
Research letter
Effective treatment of late-onset non-infectious pulmonary complication with ruxolitinib in an 8-year-old boy
Maria Di Cicco, Ester Del Tufo, Eva Parolo, Mariacristina Menconi, Sayla Bernasconi, Chiara Romei, Alessandro Di Gangi, Beatrice Masini, Diego Peroni, Gabriella Casazza

ERJ Open Research; DOI: 10.1183/23120541.00407-2021
Original research article
Health service utilisation associated with chronic breathlessness: random population sample
David C. Currow, Sungwon Chang, Magnus Ekström, Ann Hutchinson, Tim Luckett, Slavica Kochovska, Phillipa Hay, Stephen Touyz, Eleonora Dal Grande, Miriam J. Johnson

ERJ Open Research; DOI: 10.1183/23120541.00415-2021

September 09, 2021

Review
ERS International Congress 2020 virtual: highlights from the Respiratory Intensive Care Assembly
Camille Rolland-Debord, Alexander D'Haenens, Leire Mendiluce, Lydia Spurr, Shruthi Konda, Radostina Cherneva, Elodie Lhuillier, Leo Heunks, Maxime Patout

ERJ Open Research; DOI: 10.1183/23120541.00214-2021
Review
Lower airways clinical outcome measures for use in primary ciliary dyskinesia research, a scoping review
Florian Gahleitner, James Thompson, Claire L Jackson, Jana F Hueppe, Laura Behan, Eleonora Dehlink, Myrofora Goutaki, Florian Halbeisen, Ana Paula L Queiroz, Guillaume Thouvenin, Claudia Kuehni, Philipp Latzin, Jane S Lucas, Bruna Rubbo

ERJ Open Research; DOI: 10.1183/23120541.00320-2021
Original research article
Four-week daily airway clearance using oscillating positive-end expiratory pressure versus autogenic drainage in bronchiectasis patients: a randomised controlled trial
Galit Livnat, Naama Yaari, Nili Stein, Lea Bentur, Moneera Hanna, Maya Harel, Yochai Adir, Michal Shteinberg

ERJ Open Research; DOI: 10.1183/23120541.00426-2021
Original article
Normal limits for oscillometric bronchodilator responses and relationships with clinical factors
Jetmalani Kanika, Nathan J Brown, Chantale Boustany, Brett G Toelle, Guy B Marks, Michael J Abramson, David P Johns, Alan L James, Michael Hunter, Arthur W Musk, Norbert Berend, Claude S Farah, David G Chapman, Cindy Thamrin, Gregory G King

ERJ Open Research; DOI: 10.1183/23120541.00439-2021

September 02, 2021

Original research article
Suppression of epithelial abnormalities by nintedanib in induced-rheumatoid arthritis-associated interstitial lung disease mouse model
Yoko Miura, Hirotsugu Ohkubo, Akio Niimi, Satoshi Kanazawa

ERJ Open Research; DOI: 10.1183/23120541.00345-2021
Original research article
Dynamic contrast-enhanced magnetic resonance imaging of the lung reveals important pathobiology in idiopathic pulmonary fibrosis
Sydney B. Montesi, Iris Zhou, Lloyd L. Liang, Subba R. Digumarthy, Sarah Mercaldo, Nathaniel Mercaldo, Ravi T. Seethamraju, Bruce Rosen, Peter Caravan

ERJ Open Research; DOI: 10.1183/23120541.00907-2020
Original research article
Expanding clinical phage microbiology: simulating phage inhalation for respiratory tract infections
Shira Ben Porat, Daniel Gelman, Ortal Yerushalmy, Sivan Alkalay-Oren, Shunit Coppenhagen-Glazer, Malena Cohen-Cymberknoh, Eitan Kerem, Israel Amirav, Ran Nir-Paz, Ronen Hazan

ERJ Open Research; DOI: 10.1183/23120541.00367-2021
Research letter
Aerosol particle concentrations with different oxygen devices and interfaces for spontaneous breathing patients with tracheostomy: a randomized cross-over trial
Jie Li, Carla Schoenrock, James B. Fink

ERJ Open Research; DOI: 10.1183/23120541.00486-2021
Research letter
Rising COVID-19 related acute pulmonary emboli but falling national CTEPH referrals from a large national dataset
Joseph Newman, Iryna Boubriak, David Jenkins, Choo Ng, Alessandro Ruggiero, Nicholas Screaton, John Cannon, Mark Toshner

ERJ Open Research; DOI: 10.1183/23120541.00431-2021
Original article
Cross-talk of inflammatory mediators and airway epithelium reveals CFTR as a major target
Filipa B. Simões, Arthur Kmit, Margarida D. Amaral

ERJ Open Research; DOI: 10.1183/23120541.00247-2021
Original article
Acceptability of Capnography Assisted Respiratory Therapy (CART): a new mind-body intervention for chronic obstructive pulmonary disease
Anna Migliore Norweg, Anne Skamai, Simona C. Kwon, Jonathan Whiteson, Kyle MacDonald, Francois Haas, Eileen G. Collins, Roberta M. Goldring, Joan Reibman, Yinxiang Wu, Greg Sweeney, Alicia Pierre, Andrea B. Troxel, Linda Ehrlich-Jones, Naomi M. Simon

ERJ Open Research; DOI: 10.1183/23120541.00256-2021
Research letter
Protein levels, air pollution and vitamin D deficiency: links with allergy
Yong Song, E. Haydn Walters, Michael J. Abramson, Gayan Bowatte, Dinh S. Bui, Jennifer Perret, Iain Feather, Luke D. Knibbs, Richard Wilson, David S. Nichols, Shyamali C. Dharmage, Graeme R. Zosky

ERJ Open Research; DOI: 10.1183/23120541.00237-2021
Original article
Impact of fan therapy during exercise on breathlessness and recovery time in patients with chronic obstructive pulmonary disease: a pilot randomised controlled crossover trial
Alex Long, Martin Cartwright, Charles C Reilly

ERJ Open Research; DOI: 10.1183/23120541.00211-2021

August 26, 2021

Research letter
COVID-19 associated pulmonary aspergillosis: a nationwide survey by the Japanese Respiratory Society
Takahiro Takazono, Hiroshi Mukae, Koichi Izumikawa, Naoki Hasegawa, Akihito Yokoyama

ERJ Open Research; DOI: 10.1183/23120541.00402-2021
Original article
The angiostatic peptide endostatin enhances mortality risk prediction in pulmonary arterial hypertension
Catherine E. Simpson, Megan Griffiths, Jun Yang, Melanie K. Nies, R. Dhananjay Vaidya, Stephanie Brandal, Lisa J. Martin, Michael W. Pauciulo, Katie A. Lutz, Anna W. Coleman, Eric D. Austin, D. Dunbar Ivy, William C. Nichols, Allen D. Everett, Paul M. Hassoun, Rachel L. Damico

ERJ Open Research; DOI: 10.1183/23120541.00378-2021
Original research article
Exhaled volatile organic compounds and lung microbiome in chronic obstructive pulmonary disease: a pilot randomised controlled trial
D. Mohan, H. Keir, H. Richardson, D. Mayhew, J. Boyer, M. P. van der Schee, M. D. Allsworth, B. E. Miller, R. Tal-Singer, J. D. Chalmers

ERJ Open Research; DOI: 10.1183/23120541.00253-2021
Original research article
Methacholine Challenges: comparison of different tidal breathing challenge methods
James Dean, Natalie Jackson, Brett Keidel-Morgan, Daniel Hamer, Dave Singh

ERJ Open Research; DOI: 10.1183/23120541.00282-2021
Research letter
Increased smoking and e-cigarette use among Irish teenagers: A new threat to Tobacco Free Ireland 2025
Salome Sunday, Joan Hanafin, Luke Clancy

ERJ Open Research; DOI: 10.1183/23120541.00438-2021
Original research article
Breastfeeding and risk of childhood asthma: a systematic review and meta-analysis
Mike Xue, Emily Dehaas, Nagendra Chaudhary, Paul O'Byrne, Imran Satia, Om P. Kurmi

ERJ Open Research; DOI: 10.1183/23120541.00504-2021

August 19, 2021

Research letter
Dyspnea and clinical outcome in critically ill patients receiving noninvasive support for COVID-19 respiratory failure: post-hoc analysis of a randomized clinical trial
Luca S. Menga, Domenico Luca Grieco, Tommaso Rosà, Melania Cesarano, Luca Delle Cese, Cecilia Berardi, Gabriele Pintaudi, Eloisa Sofia Tanzarella, Salvatore L. Cutuli, Gennaro De Pascale, Salvatore Maurizio Maggiore, Massimo Antonelli for the COVID-ICU Gemelli study group

ERJ Open Research; DOI: 10.1183/23120541.00418-2021
Research letter
NKX2.1 (TTF1) germline mutation associated with pulmonary fibrosis and lung cancer
R Borie, B Funalot, R Epaud, C Delestrain, A Cazes, V Gounant, J Frija, MP Debray, G Zalcman, B Crestani

ERJ Open Research; DOI: 10.1183/23120541.00356-2021
Original research article
Association of antinuclear antibody seropositivity with inhaled environmental exposures in patients with interstitial lung disease
Kathleen Biblowitz, Cathryn Lee, Daisy Zhu, Imre Noth, Rekha Vij, Mary E. Strek, Shashi K. Bellam, Ayodeji Adegunsoye

ERJ Open Research; DOI: 10.1183/23120541.00254-2021
Research letter
Improvement in exercise capacity after a modified Potts shunt in an adult patient with pulmonary arterial hypertension
P. Symersky, S. M. A. Jansen, S. K. Kamminga, L. J. Meijboom, E. J. Lust, P. Eghtesady, R. M. Grady, H. J. Bogaard

ERJ Open Research; DOI: 10.1183/23120541.00287-2021

August 12, 2021

Original research article
THE AWESCORE (Alfred Wellness Score) – a patient reported outcome measure (PROM): development, feasibility, reliability, validity and responsiveness for adults with cystic fibrosis
Brenda M. Button, Lisa M. Wilson, Angela T. Burge, Lara Kimmel, Felicity Finlayson, Elyssa Williams, Anthony Talbot, Audrey Tierney, Susannah King, Anne E. Holland, Dominic Keating, Tom Kotsimbos, John W. Wilson

ERJ Open Research; DOI: 10.1183/23120541.00120-2021
Original research article
An updated approach to determine minimal clinically important differences in idiopathic pulmonary fibrosis
Mohleen Kang, Srihari Veeraraghavan, Greg S. Martin, Jordan A. Kempker

ERJ Open Research; DOI: 10.1183/23120541.00142-2021
Original research article
Prothrombotic state in patients with stable COPD: an observational study
Christos Kyriakopoulos, Christos Chronis, Evaggelia Papapetrou, Athina Tatsioni, Konstantina Gartzonika, Christina Tsaousi, Athena Gogali, Christos Katsanos, Aikaterini Vaggeli, Charikleia Tselepi, Georgios Daskalopoulos, Stavros Konstantopoulos, Konstantinos Kostikas, Athanasios Konstantinidis

ERJ Open Research; DOI: 10.1183/23120541.00297-2021
Research letter
Impact of the SARS-CoV2 pandemic on cystic fibrosis centers and care – Survey results from U.S. centers
Marianne S. Muhlebach, Fiona Cunningham, John J. LiPuma, Juyan J. Zhou, Lisa Saiman

ERJ Open Research; DOI: 10.1183/23120541.00249-2021
Original article
Lung function, COPD and Alternative Healthy Eating Index (AHEI-2010) in US adults
Kirstie Ducharme-Smith, Gustavo Mora-Garcia, Francisca de Castro Mendes, Maria Stephany Ruiz-Diaz, Andre Moreira, Rodrigo Villegas, Vanessa Garcia-Larsen

ERJ Open Research; DOI: 10.1183/23120541.00927-2020
Original research article
EBUS-guided transbronchial biopsy with or without a guide-sheath for peripheral pulmonary malignancy
Chun-Ta Huang, Lih-Yu Chang, Chung-Yu Chen, Sheng-Yuan Ruan, Ching-Kai Lin, Yi-Ju Tsai, Chao-Chi Ho, Chong-Jen Yu

ERJ Open Research; DOI: 10.1183/23120541.00267-2021
Original research article
Epidemiology and economic burden of bronchiectasis requiring hospitalisation in Singapore
Hwee Pin Phua, Wei-Yen Lim, Ganga Ganesan, Joanne Yoong, Kelvin Bryan Tan, John Arputhan Abisheganaden, Albert Yick Hou Lim

ERJ Open Research; DOI: 10.1183/23120541.00334-2021
Original research article
Oximetry neither to prescribe long-term oxygen therapy nor to screen for severe hypoxaemia
Yves Lacasse, Sébastien Thériault, Benoît St-Pierre, Sarah Bernard, Frédéric Sériès, Harold Jean Bernatchez, François Maltais

ERJ Open Research; DOI: 10.1183/23120541.00272-2021

July 29, 2021

Correspondence
Mobile video Directly Observed Therapy can be used to improve at home inhaler technique in children with asthma
Michael D Shields, James McElnay

ERJ Open Research; DOI: 10.1183/23120541.00463-2021
Research letter
Exertional multidimensional dyspnoea predicts exacerbation in stable outpatients with COPD
Masashi Kanezaki, Kunihiko Terada, Naoya Tanabe, Hiroshi Shima, Yoko Hamakawa, Susumu Sato

ERJ Open Research; DOI: 10.1183/23120541.00150-2021
Original article
Association between lung function and future risks of diabetes, asthma, myocardial infarction, hypertension and all-cause mortality
Chintal H. Shah, Robert M. Reed, Yulan Liang, Zafar Zafari

ERJ Open Research; DOI: 10.1183/23120541.00178-2021
Original research article
Xenon ventilation MRI in difficult asthma; initial experience in a clinical setting
Grace T. Mussell, Helen Marshall, Laurie J. Smith, Alberto M. Biancardi, Paul J.C. Hughes, David J. Capener, Jody Bray, Andrew J. Swift, Smitha Rajaram, Alison M. Condliffe, Guilhem J. Collier, Chris S. Johns, Nick D. Weatherley, Jim M. Wild, Ian Sabroe

ERJ Open Research; DOI: 10.1183/23120541.00785-2020
Original research article
Sputum procalcitonin – a potential biomarker in stable bronchiectasis
William Good, Gene Jeon, Irene Zeng, Louanne Storey, Helen Qiao, Stuart Jones, Sarah Mooney, Lata Jayaram, David Holland, Conroy Wong

ERJ Open Research; DOI: 10.1183/23120541.00285-2021
Research letter
An open-label study of the tolerability and potential efficacy of memantine for treating refractory chronic cough
Rayid Abdulqawi, Imran Satia, Kimberley J Holt, Rachel Dockry, Shilpi Sen, Jaclyn A Smith

ERJ Open Research; DOI: 10.1183/23120541.00447-2021

July 22, 2021

Original research article
Computed tomography total airway count predicts progression to COPD in at risk smokers
Miranda Kirby, Benjamin M. Smith, Naoya Tanabe, James C. Hogg, Harvey O. Coxson, Don D. Sin, Jean Bourbeau, Wan C. Tan for the *CanCOLD Collaborative Research Group and The Canadian Respiratory Research Network

ERJ Open Research; DOI: 10.1183/23120541.00307-2021
Original article
Anxiety and depression in Dutch patients with Primary Ciliary Dyskinesia and their caregivers: associations with health-related quality of life
Marieke Verkleij, Iris Appelman, Josje Altenburg, Jos Twisk, Alexandra L. Quittner, Eric Haarman

ERJ Open Research; DOI: 10.1183/23120541.00274-2021
Original research article
Feasibility and clinical utility of ambulatory cough monitoring in an outpatient clinical setting: a real world retrospective evaluation
Anne E. Vertigan, Sarah L. Kapela, Surinder S. Birring, Peter G. Gibson

ERJ Open Research; DOI: 10.1183/23120541.00319-2021
Original article
Bronchial thermoplasty guided by hyperpolarised gas MRI in adults with severe asthma: a 1-year pilot randomised trial
Sarah Svenningsen, Parameswaran Nair, Rachel L Eddy, Marrissa J McIntosh, Melanie Kjarsgaard, Hui Fang Lim, David G. McCormack, Gerard Cox, Grace Parraga

ERJ Open Research; DOI: 10.1183/23120541.00268-2021
Research letter
Is CPAP therapy in COVID-19 associated with an increased rate of pulmonary barotrauma?
Lewis Jones, Rebecca Nightingale, Hassan Burhan, Gareth Jones, Kimberley Barber, Helena Bond, Robert Parker, Nick Duffy, Peter Hampshire, Manish Gautam

ERJ Open Research; DOI: 10.1183/23120541.00886-2020

July 15, 2021

Original article
Outcomes and characteristics of COVID-19 patients treated with CPAP/ HFNO outside of the intensive care setting
Dominic L Sykes, Michael G Crooks, Khaing Thu Thu, Oliver I Brown, Theodore J p Tyrer, Jodie Rennardson, Catherine Littlefield, Shoaib Faruqi

ERJ Open Research; DOI: 10.1183/23120541.00318-2021

July 08, 2021

Original article
Effect of a daytrip to altitude (2500 m) on exercise performance in pulmonary hypertension – randomized cross-over trial
Simon R. Schneider, Laura C. Mayer, Mona Lichtblau, Charlotte Berlier, Esther I Schwarz, Stéphanie Saxer, Lu Tan, Michael Furian, Konrad E Bloch, Silvia Ulrich

ERJ Open Research; DOI: 10.1183/23120541.00314-2021
Original article
Utility of fractional exhaled nitric oxide suppression as a prediction tool for progression to biologic therapy
C. A. Butler, A. J. McMichael, K. Honeyford, L. Wright, J. Logan, J. Holmes, J. Busby, C. E. Hanratty, F. Yang, S. J. Smith, K. Murray, R. Chaudhuri, L. G. Heaney on behalf of the Medical Research Council UK Refractory Asthma Stratification Programme (RASP-UK)

ERJ Open Research; DOI: 10.1183/23120541.00273-2021

July 01, 2021

Study protocol
The Children's Anti-inflammatory REliever (CARE) study: a protocol for a randomised controlled trial of budesonide-formoterol as sole reliever therapy in children with mild asthma
Lee Hatter, Pepa Bruce, Mark Holliday, Augustus J Anderson, Irene Braithwaite, Andrew Corin, Allie Eathorne, Arthur Grimes, Matire Harwood, Thomas Hills, Ciléin Kearns, Kyley Kerse, John Martindale, Barney Montgomery, Lynn Riggs, Davitt Sheahan, Nick Shortt, Katja Zazulia, Mark Weatherall, David McNamara, Catherine A Byrnes, Andrew Bush, Stuart R Dalziel, Richard Beasley

ERJ Open Research; DOI: 10.1183/23120541.00271-2021

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July 29, 2021

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