ERJOR Early View

March 16, 2023

Original research article
Does hiatal hernia impact gastroesophageal reflux-related chronic cough?
Olga Truba, Joanna Żuchowska, Elżbieta M Grabczak, Katarzyna Białek-Gosk, Aleksandra Rybka-Frączek, Rafał Krenke, Marta Dąbrowska

ERJ Open Research; DOI: 10.1183/23120541.00669-2022
Original research article
Reference equations for breathlessness during incremental cycle exercise testing
Viktor Elmberg, Linus Schiöler, Thomas Lindow, Kristofer Hedman, Andrei Malinovschi, Hayley Lewthwaite, Dennis Jensen, Lars Brudin, Magnus Ekström

ERJ Open Research; DOI: 10.1183/23120541.00566-2022
Original research article
Pulmonary Artery Wedge Pressure and Left Ventricular End-Diastolic pressure during exercise in patients with dyspnea
Claudia Baratto, Andrea Faini, Gianluca p Gallone, Céline Dewachter, Giovanni Battista Perego, Antoine Bondue, Denisa Muraru, Michele Senni, Luigi p Badano, Gianfranco Parati, Jean-Luc Vachiéry, Sergio Caravita

ERJ Open Research; DOI: 10.1183/23120541.00750-2022
Research letter
The relationship between perceived and performance fatigability in severe fibrotic interstitial lung disease: a prospective, cross-sectional study
Mathieu Marillier, Mathieu Gruet, Anne-Catherine Bernard, Samuel Verges, Onofre Moran-Mendoza, J. Alberto Neder

ERJ Open Research; DOI: 10.1183/23120541.00726-2022
Original research article
Exercise intolerance in post-COVID19 survivors after hospitalization
Mariana L Lafetá, Vitor C Souza, Thaís C F Menezes, Carlos G Y Verrastro, Frederico J Mancuso, André Luis P Albuquerque, Suzana E Tanni, Meyer Izbicki, Júlio P Carlstron, Luiz Eduardo Nery, Rudolf K F Oliveira, Priscila A Sperandio, Eloara V M Ferreira

ERJ Open Research; DOI: 10.1183/23120541.00538-2022
Original research article
Reducing carbon footprint by switching to reusable soft mist inhalers
Christer Janson, Jaime Hernando Platz, Stéphane Soulard, Sue Langham, Lindsay Nicholson, Elisabeth Sophia Hartgers-Gubbels

ERJ Open Research; DOI: 10.1183/23120541.00543-2022

March 09, 2023

Original research article
Diagnostic Options for Pulmonary Fungal Diseases in Africa
Martha F. Mushi, Sherif M. Zaki, Richard O. S. Penney, Sanata Bamba, Ngouanom Kuate Marius Paulin, Kasamba L. Eric, Modeste F. Amona, Sara Werkneh, Buntung Ceesay, Bakary Dibba, Bright Ocansey, Ousmane Sy, Mohammed Yahaya, Darlinda Jiba, Tom Boyles, Sixbert I. Mkumbaye, Kwizera Richard, Elopy Sibanda, David Koffi, Yolande Sssinto Savi De Tove, Emma Orefuwa, David W. Denning

ERJ Open Research; DOI: 10.1183/23120541.00397-2022
Original research article
Outcomes of community acquired pneumonia using the Pneumonia Severity Index versus the CURB-65 in routine practice of emergency departments
Anna G. Kaal, Linde op de Hoek, Davinia T. Hochheimer, Corline Brouwers, W. Joost Wiersinga, Dominic Snijders, Katrijn L. Rensing, Christel E. van Dijk, Ewout W. Steyerberg, Cees van Nieuwkoop

ERJ Open Research; DOI: 10.1183/23120541.00051-2023
Original research article
Impact of high- and low-flow nebulized saline on airway hydration and mucociliary transport
Susyn Kelly, Matthew Valentine, Wei Hang Chua, Stanislav Tatkov

ERJ Open Research; DOI: 10.1183/23120541.00724-2022
Original research article
Short-acting β₂-agonists and exacerbations in children with asthma in England: SABINA Junior
Ann Morgan, Ekaterina Maslova, Constantinos Kallis, Ian Sinha, Graham Roberts, Trung N Tran, Ralf J p van der Valk, Jennifer K Quint

ERJ Open Research; DOI: 10.1183/23120541.00571-2022
Invited review
ERS International Congress 2022: highlights from the Thoracic Surgery and Lung Transplantation Assembly
Dimitrios E. Magouliotis, Saskia Bos, Dorina Esendagli, Marco Nardini, Marcello Migliore, Michael Perch, Giuseppe Cardillo, Federica Meloni, Sara Ricciardi, Merel Hellemons

ERJ Open Research; DOI: 10.1183/23120541.00671-2022
Original research article
Smartphone-based cough monitoring as a near real-time digital pneumonia biomarker
Maximilian Boesch, Frank Rassouli, Florent Baty, Anja Schwärzler, Sandra Widmer, Peter Tinschert, Iris Shih, David Cleres, Filipe Barata, Elgar Fleisch, Martin H. Brutsche

ERJ Open Research; DOI: 10.1183/23120541.00518-2022
Review
ERS International Congress 2022: highlights from the Paediatric Assembly
Cristina Ardura-Garcia, Katharina Kainz, Maria Christina Mallet, Laura Petrarca, Jasna Rodman Berlot, Monique Slaats, Carmen Streibel, Susanne Vijverberg, Emma E Williams, Myrofora Goutaki, Diane M Gray, Anna Lavizzari, Rory E. Morty, Marijke Proesmans, Dirk Schramm, Mirjam Stahl, Angela Zacharasiewicz, Alexander Moeller, Mariëlle W. Pijnenburg

ERJ Open Research; DOI: 10.1183/23120541.00653-2022
Original research article
Gut Microbiome Alterations in Pulmonary Hypertension in Highlanders and Lowlanders
Wenxue Dong, Lifeng Ma, Qiumin Huang, Xu Yang, Zhendong Mei, Mengmeng Kong, Zhonghan Sun, Zhiying Zhang, Jing Li, Jiaojiao Zou, Dandan Chen, Yuxiang Dai, Daxin Zhou, Yan Zheng, Longli Kang

ERJ Open Research; DOI: 10.1183/23120541.00617-2022
Original research article
Efficacy and Tolerability of Zinc Acetate for Treatment of Chronic Refractory Cough: Pilot Randomized Futility Trial
Aparna Balasubramanian, Janet T. Holbrook, Brendan J. Canning, Loretta G. Que, Mario Castro, Barry J. Make, Linda Rogers, Michael F. Busk, Alexis Rea, Ashley A. McCook-Veal, Jiaxian He, Meredith C. McCormack, Robert A. Wise on behalf of the American Lung Association Airways Clinical Research Centers

ERJ Open Research; DOI: 10.1183/23120541.00678-2022
Original research article
Evaluation of Real-World Mepolizumab Use in Severe Asthma across Europe - the SHARP experience with privacy-preserving federated analysis
Johannes A. Kroes, Rafael Alfonso-Cristancho, Aruna T. Bansal, Emmanuelle Berret, Kristina Bieksiene, Arnaud Bourdin, Luisa Brussino, Diogo Canhoto, Cristina Cardini, Gulfem Celik, Zsuzsanna Csoma, Barbro Dahlén, Ebru Damadoglu, Katrien Eger, Lisa Gauquelin, Bilun Gemicioglu, Ozlem Goksel, Sophie Graff, Enrico Heffler, Hendrik B. Hofstee, Peter Howarth, Rupert W. Jakes, Fabienne Jaun, Virginija Kalinauskaite-Zukauske, Peter Kopač, Namhee Kwon, Claudia C. Loureiro, Victor Lozoya García, Matthew Masoli, Mariana Paula Rezelj, Luis Pérez De Llano, Sanja Popović-Grle, David Ramos-Barbon, Ana Sà Sousa, Konstantinos Samitas, Florence Schleich, Concetta Sirena, Sabina Skrgat, Eleftherios Zervas, George Zichnalis, Elisabeth H. Bel, Jacob K. Sont, Simone Hashimoto, Anneke Ten Brinke

ERJ Open Research; DOI: 10.1183/23120541.00745-2022
Original research article
Normal values of respiratory oscillometry in South African children and adolescents
Shaakira Chaya, Rae MacGinty, Carvern Jacobs, Leah Githinji, Sipho Hlengwa, Shannon J Simpson, Heather J Zar, Zoltan Hantos, Diane M Gray

ERJ Open Research; DOI: 10.1183/23120541.00371-2022
Research letter
Internationally use of objective structured clinical examination (OSCEs) in respiratory training: an ERS early career member survey
Etienne-Marie Jutant, Maeva Zysman, Thomas Gille, Jonathan Messika, Bernard Maître, Maxime Patout, Lucile Sesé

ERJ Open Research; DOI: 10.1183/23120541.00706-2022

March 02, 2023

Original research article
Decreased breathing variability is associated with poorer outcome in mechanically ventilated patients
Camille Rolland-Debord, Tymothee Poitou, Come Bureau, Isabelle Rivals, Thomas Similowski, Alexandre Demoule

ERJ Open Research; DOI: 10.1183/23120541.00544-2022
Research letter
Epidemiology of unexplained chronic cough in adults: a population-based study
Johnmary T. Arinze, Tjeerd van der Veer, Daniel Bos, Bruno Stricker, Katia M. C. Verhamme, Guy Brusselle

ERJ Open Research; DOI: 10.1183/23120541.00739-2022
Original research article
Sonographic follow-up of diaphragm function in COVID-19: an exploratory study
Carlijn Veldman, Wytze S. de Boer, Huib A.M. Kerstjens, Mireille A. Edens, Jan Willem K. van den Berg

ERJ Open Research; DOI: 10.1183/23120541.00623-2022
Research letter
Safety and Feasibility of Ultrathin Probe Transbronchial Lung Cryobiopsy (UP-TBLC) without balloon blocker via Robotic Bronchoscopy in the evaluation of Peripheral Lung Lesions (PPLs): a retrospective pilot study
Ismael Matus, Juhie Patel

ERJ Open Research; DOI: 10.1183/23120541.00638-2022
Original research article
Airspace Dimension Assessment (AiDA) for early detection of lung function impairment in the peripheral airways of firefighters
Marta A. Kisiel, Gui-Hong Cai, Madeleine Petersson Sjögren, Jakob Löndahl, Jonas Jakobsson, Per Wollmer, Andrei Malinovschi, Magnus Svartengren

ERJ Open Research; DOI: 10.1183/23120541.00504-2022
Research letter
End-tidal CO₂ partial pressure is a reliable surrogate of arterial CO₂ partial pressure across different O₂, CO₂, and barometric pressures
Giorgio Manferdelli, Benjamin J. Narang, Nicolas Bourdillon, Tadej Debevec, Grégoire P. Millet

ERJ Open Research; DOI: 10.1183/23120541.00507-2022
Original research article
Investigation and outcomes in patients with non-specific pleuritis: Results from the International Collaborative Effusion (ICE) database
Anand Sundaralingam, Avinash Aujayeb, Karl A. Jackson, Emilia I. Pellas, Irfan I. Khan, Muhammad T. Chohan, Roos Joosten, Anton Boersma, Jordy Kerkhoff, Silvia Bielsa, Jose M. Porcel, Ales Rozman, Mateja Marc-Malovrh, Hugh Welch, Jenny Symonds, Stavros Anevlavis, Marios Froudrakis, Federico Mei, Lina Zuccatosta, Stefano Gasparini, Francesca Gonnelli, Inderdeep Dhaliwal, Michael A. Mitchell, Katrine Fjaellegaard, Jesper K. Petersen, Mohamed Ellayeh, Najib M. Rahman, Tom Burden, Uffe Bodtger, Coenraad F.N. Koegelenberg, Nick A. Maskell, Julius Janssen, Rahul Bhatnagar

ERJ Open Research; DOI: 10.1183/23120541.00599-2022
Study protocol
Precision Medicine Intervention in Severe Asthma (PRISM) study: molecular phenotyping of patients with severe asthma and response to biologics
Ji-Hyang Lee, Piers Dixey, Pank Bhavsar, Katie Raby, Nazanin Kermani, Marc Chadeau-Hyam, Ian M Adcock, Woo-Jung Song, Hyouk-Soo Kwon, Sei-Won Lee, You Sook Cho, Kian Fan Chung, Tae-Bum Kim

ERJ Open Research; DOI: 10.1183/23120541.00485-2022

February 23, 2023

Original research article
A randomised, controlled, feasibility trial of an online, self-guided breathlessness supportive intervention (SELF-BREATHE) for individuals with chronic breathlessness due to advanced disease
Charles C Reilly, Matthew Maddocks, Trudie Chalder, Katherine Bristowe, Irene J Higginson

ERJ Open Research; DOI: 10.1183/23120541.00508-2022
Original research article
Obstructive sleep apnoea and long-term risk of incident diabetes in middle-aged and older general population
Ali T. Siddiquee, Soriul Kim, Robert J. Thomas, Min-Hee Lee, Seung Ku Lee, Chol Shin

ERJ Open Research; DOI: 10.1183/23120541.00401-2022
Original research article
The Effects of Dual IQOS and Cigarette Smoke Exposure on Airway Epithelial Cells: Implications for Lung Health and Respiratory Disease Pathogenesis
Pritam Saha, Siddhi Jain, Ipsita Mukherjee, Samir R Panda, Amir A. Zeki, VGM Naidu, Pawan Sharma

ERJ Open Research; DOI: 10.1183/23120541.00558-2022
Original research article
Quantitative CT and visual emphysema scores: association with lung function decline
Meghan C. Koo, Wan C. Tan, Jim C. Hogg, Jean. Bourbeau, Cameron J. Hague, Jonathon A. Leipsic, Miranda Kirby

ERJ Open Research; DOI: 10.1183/23120541.00523-2022
Original research article
Functional respiratory complaints among COVID-19 survivors: a prospective cohort study
Antoine Beurnier, Laurent Savale, Xavier Jaïs, Romain Colle, Tai Pham, Luc Morin, Sophie Bulifon, Nicolas Noël, Athénaïs Boucly, Benoit Delbarre, Nathan Ebstein, Samy Figueiredo, Matthieu Gasnier, Anatole Harrois, Etienne-Marie Jutant, Mitja Jevnikar, Sophia Keddache, Anne-Lise Lecoq, Olivier Meyrignac, Florence Parent, Jérémie Pichon, Mariana Preda, Anne Roche, Andrei Seferian, Marie-France Bellin, Thomas Gille, Emmanuelle Corruble, Olivier Sitbon, Laurent Becquemont, Xavier Monnet, Marc Humbert, David Montani, Comebac Investigators

ERJ Open Research; DOI: 10.1183/23120541.00063-2023
Original research article
Risk factors for FEV1 decline in European patients with CF: data from the European Cystic Fibrosis Society Patient Registry (ECFSPR)
Elpis Hatziagorou, Steffen Fieuws, Annalisa Orenti, Lutz Naehrlich, Uros Krivec, Meir Mei-Zahav, Andreas Jung, Kris De Boeck on behalf of the ECFSPR COLLABORATIVE GROUP

ERJ Open Research; DOI: 10.1183/23120541.00449-2022

February 16, 2023

Research letter
Iron mobilization pattern in airway epithelium: tipping the immune balance in asthma
Jintao Zhang, Ziting Liang, Dong Zhang, Yun Pan, Xiaofei Liu, Rong Zeng, Wenjing Cui, Liang Dong

ERJ Open Research; DOI: 10.1183/23120541.00475-2022
Original research article
Endothelial to mesenchymal transition: a precursor to pulmonary arterial remodelling in patients with idiopathic pulmonary fibrosis
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Greg Haug, Josie Larby, Collin Chia, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal

ERJ Open Research; DOI: 10.1183/23120541.00487-2022
Research letter
Cognitive function and inhaler technique following recovery from exacerbations of COPD
Benjamin E. Henkle, Rebecca L. Freese, Mary Dahlheimer, Catherine Kane, Karin F. Hoth, Ken M. Kunisaki

ERJ Open Research; DOI: 10.1183/23120541.00627-2022

February 09, 2023

Original research article
The Short versus Long antibiotic course for pleural Infection Management (SLIM) randomised controlled open label trial
Maged Hassan, Mohamed Gad-Allah, Basma El-Shaarawy, Asmaa M El-Shazly, Cyrus Daneshvar, Ahmed S Sadaka

ERJ Open Research; DOI: 10.1183/23120541.00635-2022
Original research article
Prevalence and management of severe asthma in the Nordic countries – findings from the NORDSTAR cohort
Susanne Hansen, Anna von Bülow, Patrik Sandin, Olivia Ernstsson, Christer Janson, Lauri Lehtimäki, Hannu Kankaanranta, Charlotte Ulrik, Bernt Bøgvald Aarli, Hanna Fues Wahl, Kirk Geale, Sheila Tuyet Tang, Maija Wolf, Tom Larsen, Alan Altraja, Helena Backman, Maritta Kilpeläinen, Arja Viinanen, Dora Ludviksdottir, Paula Kauppi, Asger Sverrild, Sverre Lehmann, Vibeke Backer, Valentyna Yasinska, Tina Skjold, Jussi Karjalainen, Apostolos Bossios, Celeste Porsbjerg

ERJ Open Research; DOI: 10.1183/23120541.00687-2022
Research letter
Predictors of invasive mechanical ventilation use in patients with acute decompensated pulmonary hypertension admitted to Intensive Care Unit
Marcos V. F. Garcia, Rogerio Souza, Pedro Caruso

ERJ Open Research; DOI: 10.1183/23120541.00598-2022

February 02, 2023

Review
Impact of remote vital sign monitoring on health outcomes in acute respiratory infection and exacerbation of chronic respiratory conditions: systematic review and meta-analysis
Samuel Thomas Creavin, Megha Garg, Alastair D. Hay

ERJ Open Research; DOI: 10.1183/23120541.00393-2022
Original research article
Associations between maternal complications during pregnancy and childhood asthma: a retrospective cohort study
Ying Ma, Yu Wu, Yi Zhang, Ting Jiao, Shuangshuang Guo, Dongying Zhang, Jiewen Yang, Nali Deng, Zhijiang Liang, Harry H.X. Wang, Wei Bao, Ruoling Chen, Jie Tang, Xiaoqin Liu

ERJ Open Research; DOI: 10.1183/23120541.00548-2022
Original research article
What is the optimal management of potentially resectable stage III-N2 NSCLC? Results of a fixed effects network meta-analysis and economic modelling
Matthew Evison, Ross Maconachie, Toby Mercer, Caitlin H Daly, Nicky J. Welton, Shahzeena Aslam, Doug West, Neal Navani

ERJ Open Research; DOI: 10.1183/23120541.00299-2022
Study protocol
The national chronic obstructive pulmonary disease screening program in China: rationale and design
Jieping Lei, Ke Huang, Jun Pan, Wei Li, Hongtao Niu, Xiaoxia Ren, Fen Dong, Yong Li, Baicun Li, Cunbo Jia, Ting Yang, Chen Wang on behalf of the China National Chronic Obstructive Pulmonary Disease Screening Program Investigators

ERJ Open Research; DOI: 10.1183/23120541.00597-2022
Original research article
Validation of the HULL Score clinical prediction rule (CPR) for unsuspected pulmonary embolism in ambulatory cancer patients
Farzana Haque, Jessamine Ryde, Laura Broughton, Chao Huang, Sifut Sethi, Andrew Stephens, Annet Pillai, Shagufta Mirza, Victoria Brown, Ged Avery, Georgios Bozas, Anthony Maraveyas

ERJ Open Research; DOI: 10.1183/23120541.00651-2022
Original research article
Variability in P2X Receptor Composition in Human Taste Nerves: Implications for Treatment of Chronic Cough
Brigit High, Marie E. Jetté, Mei Li, Vijay R. Ramakrishnan, Matthew Clary, Jeremy Prager, Julia Draf, Thomas Hummel, Thomas E. Finger

ERJ Open Research; DOI: 10.1183/23120541.00007-2023
Original research article
Clinical impact of routine sleep-assessment by peripheral arterial tonometry in patients with Chronic Obstructive Pulmonary Disease
Daniel Hansson, Anders Andersson, Lowie E. G. W. Vanfleteren, Kristina Andelid, Ding Zou, Jan Hedner, Ludger Grote

ERJ Open Research; DOI: 10.1183/23120541.00458-2022
Original research article
The effect of D-cycloserine on brain processing of breathlessness over pulmonary rehabilitation - an experimental medicine study
Sarah L. Finnegan, Olivia K. Harrison, Sara Booth, Andrea Dennis, Martyn Ezra, Catherine J. Harmer, Mari Herigstad, Bryan Guillaume, Thomas E. Nichols, Najib M. Rahman, Andrea Reinecke, Olivier Renaud, Kyle T.S. Pattinson

ERJ Open Research; DOI: 10.1183/23120541.00479-2022
Original research article
Awake prone position in COVID-19 acute respiratory failure: a randomized crossover study using electrical impedance tomography
Thomas Brunelle, Eloi Prud'homme, Jean-Emmanuel Alphonsine, Karine Baumstarck, Celine Sanz, Saida Salmi, Noemie Peres, Jean-Marie Forel, Laurent Papazian, Sami Hraiech, Antoine Roch, Christophe Guervilly

ERJ Open Research; DOI: 10.1183/23120541.00509-2022
Research letter
Airway wall splice-QTL analysis reveals novel downstream mechanisms for known asthma-SNPs
Tessa M. Kole, Simon D. Pouwels, Rene Bults, Marlies E. Ketelaar, Victor Guryev, Lisanne Koll, Huib A.M. Kerstjens, Martijn C. Nawijn, Alen Faiz, Maarten van den Berge

ERJ Open Research; DOI: 10.1183/23120541.00413-2022
Original research article
Delineating associations of progressive pleuroparenchymal fibroelastosis in patients with pulmonary fibrosis
Eyjolfur Gudmundsson, An Zhao, Nesrin Mogulkoc, Frouke van Beek, Tinne Goos, Christopher J. Brereton, Marcel Veltkamp, Robert Chapman, Hendrik W. van Es, Helen Garthwaite, Bahareh Gholipour, Melissa Heightman, Arjun Nair, Katarina Pontoppidan, Recep Savas, Asia Ahmed, Marie Vermant, Omer Unat, Alex Procter, Laurens De Sadeleer, Emma Denneny, Timothy Wallis, Mark Duncan, Magali Taylor, Stijn Verleden, Sam M. Janes, Daniel C. Alexander, Athol U. Wells, Joanna Porter, Mark G Jones, Iain Stewart, Coline H.M. van Moorsel, Wim Wuyts, Joseph Jacob

ERJ Open Research; DOI: 10.1183/23120541.00637-2022
Original research article
Differences in acoustic features of cough by pneumonia severity in patients with COVID-19: a cross-sectional study
Clare Davidson, Osw Antonio Caguana, Manuel Lozano-García, Mariela Arita Guevara, Luis Estrada-Petrocelli, Ignasi Ferrer-Lluis, Yolanda Castillo-Escario, Pilar Ausín, Joaquim Gea, Raimon Jané

ERJ Open Research; DOI: 10.1183/23120541.00247-2022

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March 16, 2023

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March 09, 2023

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February 23, 2023

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February 16, 2023

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