ERJOR Early View

February 23, 2023

Original research article
The Effects of Dual IQOS and Cigarette Smoke Exposure on Airway Epithelial Cells: Implications for Lung Health and Respiratory Disease Pathogenesis
Pritam Saha, Siddhi Jain, Ipsita Mukherjee, Samir R Panda, Amir A. Zeki, VGM Naidu, Pawan Sharma

ERJ Open Research; DOI: 10.1183/23120541.00558-2022
Original research article
A randomised, controlled, feasibility trial of an online, self-guided breathlessness supportive intervention (SELF-BREATHE) for individuals with chronic breathlessness due to advanced disease
Charles C Reilly, Matthew Maddocks, Trudie Chalder, Katherine Bristowe, Irene J Higginson

ERJ Open Research; DOI: 10.1183/23120541.00508-2022

February 16, 2023

Research letter
Iron mobilization pattern in airway epithelium: tipping the immune balance in asthma
Jintao Zhang, Ziting Liang, Dong Zhang, Yun Pan, Xiaofei Liu, Rong Zeng, Wenjing Cui, Liang Dong

ERJ Open Research; DOI: 10.1183/23120541.00475-2022
Original research article
Endothelial to mesenchymal transition: a precursor to pulmonary arterial remodelling in patients with idiopathic pulmonary fibrosis
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Greg Haug, Josie Larby, Collin Chia, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal

ERJ Open Research; DOI: 10.1183/23120541.00487-2022
Research letter
Cognitive function and inhaler technique following recovery from exacerbations of COPD
Benjamin E. Henkle, Rebecca L. Freese, Mary Dahlheimer, Catherine Kane, Karin F. Hoth, Ken M. Kunisaki

ERJ Open Research; DOI: 10.1183/23120541.00627-2022

February 09, 2023

Original research article
The Short versus Long antibiotic course for pleural Infection Management (SLIM) randomised controlled open label trial
Maged Hassan, Mohamed Gad-Allah, Basma El-Shaarawy, Asmaa M El-Shazly, Cyrus Daneshvar, Ahmed S Sadaka

ERJ Open Research; DOI: 10.1183/23120541.00635-2022
Original research article
Prevalence and management of severe asthma in the Nordic countries – findings from the NORDSTAR cohort
Susanne Hansen, Anna von Bülow, Patrik Sandin, Olivia Ernstsson, Christer Janson, Lauri Lehtimäki, Hannu Kankaanranta, Charlotte Ulrik, Bernt Bøgvald Aarli, Hanna Fues Wahl, Kirk Geale, Sheila Tuyet Tang, Maija Wolf, Tom Larsen, Alan Altraja, Helena Backman, Maritta Kilpeläinen, Arja Viinanen, Dora Ludviksdottir, Paula Kauppi, Asger Sverrild, Sverre Lehmann, Vibeke Backer, Valentyna Yasinska, Tina Skjold, Jussi Karjalainen, Apostolos Bossios, Celeste Porsbjerg

ERJ Open Research; DOI: 10.1183/23120541.00687-2022
Research letter
Predictors of invasive mechanical ventilation use in patients with acute decompensated pulmonary hypertension admitted to Intensive Care Unit
Marcos V. F. Garcia, Rogerio Souza, Pedro Caruso

ERJ Open Research; DOI: 10.1183/23120541.00598-2022

February 02, 2023

Original research article
Associations between maternal complications during pregnancy and childhood asthma: a retrospective cohort study
Ying Ma, Yu Wu, Yi Zhang, Ting Jiao, Shuangshuang Guo, Dongying Zhang, Jiewen Yang, Nali Deng, Zhijiang Liang, Harry H.X. Wang, Wei Bao, Ruoling Chen, Jie Tang, Xiaoqin Liu

ERJ Open Research; DOI: 10.1183/23120541.00548-2022
Original research article
What is the optimal management of potentially resectable stage III-N2 NSCLC? Results of a fixed effects network meta-analysis and economic modelling
Matthew Evison, Ross Maconachie, Toby Mercer, Caitlin H Daly, Nicky J. Welton, Shahzeena Aslam, Doug West, Neal Navani

ERJ Open Research; DOI: 10.1183/23120541.00299-2022
Study protocol
The national chronic obstructive pulmonary disease screening program in China: rationale and design
Jieping Lei, Ke Huang, Jun Pan, Wei Li, Hongtao Niu, Xiaoxia Ren, Fen Dong, Yong Li, Baicun Li, Cunbo Jia, Ting Yang, Chen Wang on behalf of the China National Chronic Obstructive Pulmonary Disease Screening Program Investigators

ERJ Open Research; DOI: 10.1183/23120541.00597-2022
Original research article
Validation of the HULL Score clinical prediction rule (CPR) for unsuspected pulmonary embolism in ambulatory cancer patients
Farzana Haque, Jessamine Ryde, Laura Broughton, Chao Huang, Sifut Sethi, Andrew Stephens, Annet Pillai, Shagufta Mirza, Victoria Brown, Ged Avery, Georgios Bozas, Anthony Maraveyas

ERJ Open Research; DOI: 10.1183/23120541.00651-2022
Original research article
Variability in P2X Receptor Composition in Human Taste Nerves: Implications for Treatment of Chronic Cough
Brigit High, Marie E. Jetté, Mei Li, Vijay R. Ramakrishnan, Matthew Clary, Jeremy Prager, Julia Draf, Thomas Hummel, Thomas E. Finger

ERJ Open Research; DOI: 10.1183/23120541.00007-2023
Original research article
The effect of D-cycloserine on brain processing of breathlessness over pulmonary rehabilitation - an experimental medicine study
Sarah L. Finnegan, Olivia K. Harrison, Sara Booth, Andrea Dennis, Martyn Ezra, Catherine J. Harmer, Mari Herigstad, Bryan Guillaume, Thomas E. Nichols, Najib M. Rahman, Andrea Reinecke, Olivier Renaud, Kyle T.S. Pattinson

ERJ Open Research; DOI: 10.1183/23120541.00479-2022
Original research article
Clinical impact of routine sleep-assessment by peripheral arterial tonometry in patients with Chronic Obstructive Pulmonary Disease
Daniel Hansson, Anders Andersson, Lowie E. G. W. Vanfleteren, Kristina Andelid, Ding Zou, Jan Hedner, Ludger Grote

ERJ Open Research; DOI: 10.1183/23120541.00458-2022
Research letter
Airway wall splice-QTL analysis reveals novel downstream mechanisms for known asthma-SNPs
Tessa M. Kole, Simon D. Pouwels, Rene Bults, Marlies E. Ketelaar, Victor Guryev, Lisanne Koll, Huib A.M. Kerstjens, Martijn C. Nawijn, Alen Faiz, Maarten van den Berge

ERJ Open Research; DOI: 10.1183/23120541.00413-2022
Original research article
Differences in acoustic features of cough by pneumonia severity in patients with COVID-19: a cross-sectional study
Clare Davidson, Osw Antonio Caguana, Manuel Lozano-García, Mariela Arita Guevara, Luis Estrada-Petrocelli, Ignasi Ferrer-Lluis, Yolanda Castillo-Escario, Pilar Ausín, Joaquim Gea, Raimon Jané

ERJ Open Research; DOI: 10.1183/23120541.00247-2022
Original research article
Incidence of cognitive impairment and dementia after hospitalisation for pneumonia: a UK population-based matched cohort study
Christos V. Chalitsios, Vadsala Baskaran, Rowan H. Harwood, Wei Shen Lim, Tricia M. McKeever

ERJ Open Research; DOI: 10.1183/23120541.00328-2022
Review
Impact of remote vital sign monitoring on health outcomes in acute respiratory infection and exacerbation of chronic respiratory conditions: systematic review and meta-analysis
Samuel Thomas Creavin, Megha Garg, Alastair D. Hay

ERJ Open Research; DOI: 10.1183/23120541.00393-2022
Research letter
Home monitoring of lung mechanics by oscillometry before, during and after severe COVID-19 disease: a case study
Chiara Veneroni, Roberto Perissin, Fabiano Di Marco, Raffaele L. Dellaca

ERJ Open Research; DOI: 10.1183/23120541.00480-2022

January 26, 2023

Original research article
Registry on the treatment of central and complex sleep-disordered breathing with adaptive servo-ventilation (READ-ASV): protocol and cohort profile
Michael Arzt, Oliver Munt, Jean-Louis Pépin, Raphael Heinzer, Raphaela Kübeck, Ulrike von Hehn, Daniela Ehrsam-Tosi, Adam Benjafield, Holger Woehrle for the READ-ASV investigators

ERJ Open Research; DOI: 10.1183/23120541.00618-2022
Original research article
Hospitalisation Outcomes in Pneumococcal Vaccinated Versus Unvaccinated Patients with Exacerbation of COPD – Results From The HOPE COPD Study
Rajesh Venkitakrishnan, Anand Vijay, Jolsana Augustine, Divya Ramachandran, Melcy Cleetus, Aparna S Nirmal, Susan John

ERJ Open Research; DOI: 10.1183/23120541.00476-2022
Original research article
Moderate to severe ARDS: COVID-19 patients compared to influenza patients for ventilator parameters and mortality
Adel Maamar, Pauline Guillot, Vincent Joussellin, Flora Delamaire, Benoit Painvin, Anaëlle Bichon, Océane Bernard de la Jartre, Matteo Mauget, Mathieu Lesouhaitier, Jean Marc Tadié, Nicolas Terzi, Arnaud Gacouin

ERJ Open Research; DOI: 10.1183/23120541.00554-2022
Invited review
ERS International congress 2022: highlights from the respiratory infections assembly
Radhika Banka, Kiarina Chichirelo-Konstantynovych, Katie L. Horton, Tetyana Konstantynovych, Merete B. Long, Melissa J. McDonnell, Oliver W. Meldrum, Mirae Park, Lidia Perea, Oksana Viltsaniuk, Holly R. Keir

ERJ Open Research; DOI: 10.1183/23120541.00628-2022
Invited review
ERS International Congress, 2022: highlights from the Epidemiology and Environment Assembly
James GH Parkin, Laura Delgado-Ortiz, Rosalie Delvert, Manosij Ghosh, Aliki Korkontzelou, Sarang Patil, Marine Savouré, Mateusz Jankowski, Orianne Dumas

ERJ Open Research; DOI: 10.1183/23120541.00574-2022
Original research article
Inhaled formoterol impairs aerobic exercise capacity in endurance-trained individuals: a randomised controlled trial
Søren Jessen, Anders Lemminger, Vibeke Backer, Mads Fischer, Andrea Di Credico, Andreas Breenfeldt Andersen, Jens Bangsbo, Morten Hostrup

ERJ Open Research; DOI: 10.1183/23120541.00643-2022
Original research article
Adding a biologic to allergen immunotherapy increases treatment efficacy
Andrzej Bożek, Andreas Fischer, Agnieszka Bogacz-Piaseczynska, Giorgio Walter Canonica

ERJ Open Research; DOI: 10.1183/23120541.00639-2022
Invited review
ERS international congress 2022: Highlights from Assembly 2 on respiratory intensive care
Simon Valentin, Daniel Lopez Padilla, Santi Nolasco, Darjan Ranilović, Raquel Guillamat-Prats, Toni Marín, Sharlene Ho, Shannon Tang, Efthymia Papadopoulou, Joseph Malone, Sebastian Leiva Agüero, Chloé Cantero, Maxime Patout, Christoph Fisser

ERJ Open Research; DOI: 10.1183/23120541.00532-2022
Review
Early Prediction of Bronchopulmonary Dysplasia: Can Noninvasive Monitoring Methods be Essential?
Xuewei Cui, Jianhua Fu

ERJ Open Research; DOI: 10.1183/23120541.00621-2022
Original research article
Clinical response to benralizumab can be predicted by combining clinical outcomes at 3 months with baseline characteristics
Johannes A. Kroes, Kim de Jong, Simone Hashimoto, Sander W. Zielhuis, Eric N van Roon, Jacob K. Sont, Anneke ten Brinke on behalf of the RAPSODI team

ERJ Open Research; DOI: 10.1183/23120541.00559-2022
Invited review
ERS international Congress 2022: highlights from the Basic and Translational Science Assembly
Sara Cuevas Ocaña, Natalia El-Merhie, Merian E. Kuipers, Mareike Lehmann, Sara Rolandsson Enes, Carola Voss, Lareb S. N. Dean, Matthew Loxham, Agnes W. Boots, Suzanne M. Cloonan, Catherine M. Greene, Irene H. Heijink, Audrey Joannes, Arnaud A. Mailleux, Nahal Mansouri, Niki L. Reynaert, Anne M. van der Does, Darcy E. Wagner, Niki Ubags

ERJ Open Research; DOI: 10.1183/23120541.00561-2022
Invited review
ERS International Congress 2022: Sleep Medicine Highlights from Assembly 4
Matteo Bradicich, Matteo Siciliano, Enrico Schiavi, Edoardo Amante, Chloé Cantero, Amany F. Elbehairy, Andrea Portacci, Michail Fanaridis, Dries Testelmans, Winfried Randerath, Sophia Schiza

ERJ Open Research; DOI: 10.1183/23120541.00582-2022
Original research article
Modifiable lifestyle risk factors for sarcoidosis: a nested case-control study
Marina Dehara, Michael C. Sachs, Johan Grunewald, Anders Blomberg, Elizabeth V. Arkema

ERJ Open Research; DOI: 10.1183/23120541.00492-2022
Original research article
EBUS-guided transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: safety, feasibility and diagnostic yield – experience in 50 cases
M Ariza-Prota, J Pérez-Pallarés, A Fernández-Fernández, L García-Alfonso, JA Cascón, H Torres-Rivas, L Fernández-Fernández, I Sánchez, M Gil, M García-Clemente, F López-González

ERJ Open Research; DOI: 10.1183/23120541.00448-2022
Original research article
Plasma Sphingolipids, Lung Function, and Chronic Obstructive Lung Disease: The Cardiovascular Health Study
Arya R. Gharib, Paul N. Jensen, Bruce M. Psaty, Andrew N. Hoofnagle, David Siscovick, Sina A. Gharib, Colleen M. Sitlani, Nona Sotoodehnia, Rozenn N. Lemaitre

ERJ Open Research; DOI: 10.1183/23120541.00346-2022
Original research article
Phenotyping empyema by pleural fluid culture results and macroscopic appearance: an 8-year retrospective study
Ka Pang Chan, Susanna So Shan Ng, Kwun Cheung Ling, Ka Ching Ng, Lai Ping Lo, Wing Ho Yip, Jenny Chun Li Ngai, Kin Wang To, Fanny Wai San Ko, Yun Chor Gary Lee, David Shu Cheong Hui

ERJ Open Research; DOI: 10.1183/23120541.00534-2022
Review
Definitions of non-response and response to biological therapy for severe asthma: a systematic review
Ekaterina Khaleva, Anna Rattu, Chris Brightling, Andrew Bush, Arnaud Bourdin, Apostolos Bossios, Kian Fan Chung, Rekha Chaudhuri, Courtney Coleman, Ratko Djukanovic, Sven-Erik Dahlén, Andrew Exley, Louise Fleming, Stephen J Fowler, Atul Gupta, Eckard Hamelmann, Gerard H. Koppelman, Erik Melén, Vera Mahler, Paul Seddon, Florian Singer, Celeste Porsbjerg, Valeria Ramiconi, Franca Rusconi, Valentyna Yasinska, Graham Roberts on behalf of the 3TR definition of response working group

ERJ Open Research; DOI: 10.1183/23120541.00444-2022
Original research article
Outcome prediction model and prognostic biomarkers for COVID-19 patients in Vietnam
Hien Thi Thu Nguyen, Vang Le-Quy, Son Van Ho, Jakob Holm Dalsgaard Thomsen, Malene Pontoppidan Stoico, Hoang Van Tong, Nhat-Linh Nguyen, Henrik Bygum Krarup, Son Hong Nguyen, Viet Quoc Tran, Nguyen Linh Toan, Anh Tuan Dinh-Xuan

ERJ Open Research; DOI: 10.1183/23120541.00481-2022
Study protocol
Functional imaging in asthma and COPD: design of the NOVELTY ADPro substudy
Helen Marshall, Jim M. Wild, Laurie J. Smith, Latife Hardaker, Titti Fihn-Wikander, Hana Müllerová, Rod Hughes for the NOVELTY study investigators

ERJ Open Research; DOI: 10.1183/23120541.00344-2022
Original research article
Clinical characteristics and PAP adherence among elderly European sleep apnoea patients from the ESADA cohort
Aino Lammintausta, Ulla Anttalainen, Özen K. Basoglu, Maria R. Bonsignore, Haralampos Gouveris, Ludger Grote, Jan Hedner, Ondrej Ludka, Stefan Mihaicuta, Athanasia Pataka, Georgia Trakada, Mafalda van Zeller, Tarja Saaresranta on behalf of the ESADA Study Group

ERJ Open Research; DOI: 10.1183/23120541.00506-2022

January 05, 2023

Invited review
ERS International Congress 2022: highlights from the Interstitial Lung Diseases Assembly
Theodoros Karampitsakos, Phuong Phuong Diep, Daan W. Loth, Iftikhar Nadeem, Elene Khurtsidze, Marlies S. Wijsenbeek, Wim A. Wuyts, Elena Bargagli, Antoine Froidure, Paolo Spagnolo, Marcel Veltkamp, Maria Molina-Molina, Cormac McCarthy, Katerina M. Antoniou, Michael Kreuter, Catharina C. Moor

ERJ Open Research; DOI: 10.1183/23120541.00584-2022

December 22, 2022

Original research article
Conservative oxygen supplementation during Helmet CPAP therapy in patients with COVID-19 and respiratory failure: A pilot study
Alessandra Iacovelli, Maria Luisa Nicolardi, Valentina Baccolini, Federica Olmati, Ilenia Attilia, Pia Baiocchi, Letizia D'Antoni, Ilaria Menichini, Ambra Migliarini, Daniela Pellegrino, Angelo Petroianni, Daniel Piamonti, Angela Tramontano, Paolo Villari, Paolo Palange

ERJ Open Research; DOI: 10.1183/23120541.00455-2022

December 14, 2022

Review
Pleural effusion due to non-malignant gastrointestinal disease
Lucía Ferreiro, Ana Casal, Mª Elena Toubes, Juan Suárez-Antelo, Antonio Golpe, Romina Abelleira-París, Vanessa Riveiro, José Manuel Álvarez-Dobaño, Luis Valdés

ERJ Open Research; DOI: 10.1183/23120541.00290-2022

December 08, 2022

Invited review
Roles of real-world evidence in severe asthma treatment: challenges and opportunities
Youngsoo Lee, Ji-Hyang Lee, So Young Park, Ji-Ho Lee, Joo-Hee Kim, Hyun Jung Kim, Sang-Heon Kim, Kian Fan Chung, Woo-Jung Song

ERJ Open Research; DOI: 10.1183/23120541.00248-2022

December 01, 2022

Original research article
Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD
Ventzislava A. Hristova, Alastair Watson, Raghothama Chaerkady, Matthew S. Glover, Jodie Ackland, Bastian Angerman, Graham Belfield, Maria G. Belvisi, Hannah Burke, Doriana Cellura, Howard W. Clark, Damla Etal, Anna Freeman, Ashley I Heinson, Sonja Hess, Michael Hühn, Emily Hall, Alex Mackay, Jens Madsen, Christopher McCrae, Daniel Muthas, Steven Novick, Kristoffer Ostridge, Lisa Öberg, Adam Platt, Anthony D. Postle, C. Mirella Spalluto, Outi Vaarala, Junmin Wang, Karl J. Staples, Tom M.A Wilkinson on behalf of the MICA II Study group

ERJ Open Research; DOI: 10.1183/23120541.00378-2022

November 17, 2022

Original research article
Effect of acetazolamide on pulmonary vascular hemodynamics in patients with COPD going to altitude: a randomized, placebo-controlled, double-blind trial
Mona Lichtblau, Stéphanie Saxer, Laura Mayer, Ulan Sheraliev, Maamed Mademilov, Michael Furian, Aline Buergin, Philipp M. Schweiwiller, Simon R. Schneider, Felix C. Tanner, Talant Sooronbaev, Konrad E Bloch, Silvia Ulrich

ERJ Open Research; DOI: 10.1183/23120541.00412-2022

November 03, 2022

Original research article
Lung diffusing capacities for nitric oxide and carbon monoxide at rest and post-walking in long COVID
Giovanni Barisione, Vito Brusasco

ERJ Open Research; DOI: 10.1183/23120541.00363-2022

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