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  • Severe pulmonary hypertension associated with lung disease is characterised by a loss of small pulmonary vessels on quantitative computed tomography
    In patients with pulmonary hypertension associated with lung disease, reduced small pulmonary vessel volume on quantitative CT imaging identifies patients with severe pulmonary hypertension
  • Noninvasive diagnosis of pulmonary hypertension with hyperpolarised 129Xe magnetic resonance imaging and spectroscopy
    Diagnostic models using 129Xe MRI/MRS metrics can noninvasively detect pre-capillary PH, post-capillary PH and ILD. The combination of 129Xe MRI/MRS provides a comprehensive assessment of haemodynamics and gas-exchange impairment in individual patients.
  • Lung involvement during the prediagnostic phase of idiopathic pleuroparenchymal fibroelastosis
    Patients with PPFE sometimes have lung involvement at the lung apex long before the diagnosis. The prediagnostic phase with apical fibrosis is much longer than the postdiagnostic phase in patients with PPFE.
  • Heparan sulfate mimetic fucoidan restores the endothelial glycocalyx and protects against dysfunction induced by serum of COVID-19 patients in the intensive care unit
    The heparan sulfate mimetic fucoidan reduces endothelial activation induced by severe COVID-19 serum, restores the endothelial glycocalyx and the cell–cell barrier, and reverses the endothelial pro-coagulable state
  • Autoimmune pulmonary alveolar proteinosis in children
    In children, management of autoimmune pulmonary alveolar proteinosis is very challenging. We need to consider all treatment options, as the most effective one with the best harm-to-benefit ratio is unknown.
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Latest Articles

  • Severe pulmonary hypertension associated with lung disease is characterised by a loss of small pulmonary vessels on quantitative computed tomography
    Dheyaa Alkhanfar, Yousef Shahin, Faisal Alandejani, Krit Dwivedi, Samer Alabed, Chris Johns, Allan Lawrie, A.A. Roger Thompson, Alexander M.K. Rothman, Juerg Tschirren, Johanna M. Uthoff, Eric Hoffman, Robin Condliffe, Jim M. Wild, David G. Kiely, Andrew J. Swift
    ERJ Open Research Apr 2022, 8 (2) 00503-2021; DOI: 10.1183/23120541.00503-2021
  • Vitamin D replacement in children with acute wheeze: a dose-escalation study
    Christos Stefanidis, Andrew Bush, Christopher Newby, Chinedu Nwokoro, Susan Liebeschuetz, Imogen P. Skene, Christopher J. Griffiths, Adrian R. Martineau
    ERJ Open Research Apr 2022, 8 (2) 00609-2021; DOI: 10.1183/23120541.00609-2021
  • Longitudinal passive cough monitoring and its implications for detecting changes in clinical status
    Juan C. Gabaldón-Figueira, Eric Keen, Matthew Rudd, Virginia Orrilo, Isabel Blavia, Juliane Chaccour, Mindaugas Galvosas, Peter Small, Simon Grandjean Lapierre, Carlos Chaccour
    ERJ Open Research Apr 2022, 8 (2) 00001-2022; DOI: 10.1183/23120541.00001-2022
  • Safety of prolonged treatment with bedaquiline in programmatic conditions
    Dzmitriy Zhurkin, Elmira Gurbanova, Jonathon R. Campbell, Dick Menzies, Svetlana Setkina, Hennadz Hurevich, Varvara Solodovnikova, Dzmitry Viatushka, Alan Altraja, Alena Skrahina
    ERJ Open Research Apr 2022, 8 (2) 00685-2021; DOI: 10.1183/23120541.00685-2021
  • Noninvasive diagnosis of pulmonary hypertension with hyperpolarised 129Xe magnetic resonance imaging and spectroscopy
    Elianna A. Bier, Fawaz Alenezi, Junlan Lu, Ziyi Wang, Joseph G. Mammarappallil, Bryan O'Sullivan-Murphy, Alaattin Erkanli, Bastiaan Driehuys, Sudarshan Rajagopal
    ERJ Open Research Apr 2022, 8 (2) 00035-2022; DOI: 10.1183/23120541.00035-2022
  • Causes and outcomes of ICU hospitalisations in patients with pulmonary arterial hypertension
    Mario Naranjo, Valentina Mercurio, Hussein Hassan, Noura Alturaif, Alessandra Cuomo, Umberto Attanasio, Nermin Diab, Sarina K. Sahetya, Monica Mukherjee, Steven Hsu, Aparna Balasubramanian, Catherine E. Simpson, Rachel Damico, Todd M. Kolb, Stephen C. Mathai, Paul M. Hassoun
    ERJ Open Research Apr 2022, 8 (2) 00002-2022; DOI: 10.1183/23120541.00002-2022
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About ERJ Open Research

ERJ Open Research is a new fully open access original research journal, published online by the European Respiratory Society. The journal aims to publish high-quality work in all fields of respiratory science and medicine, covering basic science, clinical translational science and clinical medicine.

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