TY - JOUR T1 - Acute myocardial infarction <em>versus</em> other cardiovascular events in community-acquired pneumonia JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00020-2015 VL - 1 IS - 1 SP - 00020-2015 AU - Stefano Aliberti AU - Julio Ramirez AU - Roberto Cosentini AU - Vincenzo Valenti AU - Antonio Voza AU - Paolo Rossi AU - Daiana Stolz AU - Delfino Legnani AU - Alberto Pesci AU - Luca Richeldi AU - Paula Peyrani AU - Fernando Maria Massari AU - Francesco Blasi Y1 - 2015/05/01 UR - http://openres.ersjournals.com/content/1/1/00020-2015.abstract N2 - The aim of the present study was to define the prevalence, characteristics, risk factors and impact on clinical outcomes of acute myocardial infarction (AMI) versus other cardiovascular events (CVEs) in patients with community-acquired pneumonia (CAP).This was an international, multicentre, observational, prospective study of CAP patients hospitalised in eight hospitals in Italy and Switzerland. Three groups were identified: those without CVEs, those with AMI and those with other CVEs.Among 905 patients, 21 (2.3%) patients experienced at least one AMI, while 107 (11.7%) patients experienced at least one other CVE. Patients with CAP and either AMI or other CVEs showed a higher severity of the disease than patients with CAP alone. Female sex, liver disease and the presence of severe sepsis were independent predictors for the occurrence of AMI, while female sex, age &gt;65 years, neurological disease and the presence of pleural effusion predicted other CVEs. In-hospital mortality was significantly higher among those who experienced AMI in comparison to those experiencing other CVEs (43% versus 21%, p=0.039). The presence of AMI showed an adjusted odds ratio for in-hospital mortality of 3.57 (p=0.012) and for other CVEs of 2.63 (p=0.002).These findings on AMI versus other CVEs as complications of CAP may be important when planning interventional studies on cardioprotective medications.Acute myocardial infarction is associated with specific risk factors and accounts for worse outcomes in CAP patients http://ow.ly/QhT2t ER -