RT Journal Article
SR Electronic
T1 The effect of adenotonsillectomy for childhood sleep apnoea on cardiorespiratory control
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP 00003-2016
DO 10.1183/23120541.00003-2016
VO 2
IS 2
A1 Mathias Baumert
A1 Yvonne Pamula
A1 James Martin
A1 Declan Kennedy
A1 Anand Ganesan
A1 Muammar Kabir
A1 Mark Kohler
A1 Sarah A. Immanuel
YR 2016
UL http://openres.ersjournals.com/content/2/2/00003-2016.abstract
AB The efficacy of adenotonsillectomy for relieving obstructive sleep apnoea symptoms in children has been firmly established, but its precise effects on cardiorespiratory control are poorly understood.In 375 children enrolled in the Childhood Adenotonsillectomy Trial, randomised to undergo either adenotonsillectomy (n=194) or a strategy of watching waiting (n=181), respiratory rate, respiratory sinus arrhythmia and heart rate were analysed during quiet, non-apnoeic and non-hypopnoeic breathing throughout sleep at baseline and at 7 months using overnight polysomnography.Children who underwent early adenotonsillectomy demonstrated an increase in respiratory rate post-surgery while the watchful waiting group showed no change. Heart rate and respiratory sinus arrhythmia were comparable between both arms. On assessing cardiorespiratory variables with regard to normalisation of clinical polysomnography findings during follow-up, heart rate was reduced in children who had resolution of obstructive sleep apnoea syndrome, while no differences in their respiratory rate or respiratory sinus arrhythmia were observed.Adenotonsillectomy for obstructive sleep apnoea increases baseline respiratory rate during sleep. Normalisation of apnoea–hypopnoea index, spontaneously or via surgery, lowers heart rate. Considering the small average effect size, the clinical significance is uncertain.Adenotonsillectomy for childhood obstructive sleep apnoea increases respiratory rate during sleep http://ow.ly/Dptd300w9Pp