RT Journal Article
SR Electronic
T1 Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP 00092-2017
DO 10.1183/23120541.00092-2017
VO 3
IS 4
A1 Gennaro De Pascale
A1 Otavio T. Ranzani
A1 Saad Nseir
A1 Jean Chastre
A1 Tobias Welte
A1 Massimo Antonelli
A1 Paolo Navalesi
A1 Eugenio Garofalo
A1 Andrea Bruni
A1 Luis Miguel Coelho
A1 Szymon Skoczynski
A1 Federico Longhini
A1 Fabio Silvio Taccone
A1 David Grimaldi
A1 Helmut J.F. Salzer
A1 Christoph Lange
A1 Filipe Froes
A1 Antoni Artigas
A1 Emili Díaz
A1 Jordi Vallés
A1 Alejandro Rodríguez
A1 Mauro Panigada
A1 Vittoria Comellini
A1 Luca Fasano
A1 Paolo M. Soave
A1 Giorgia Spinazzola
A1 Charles-Edouard Luyt
A1 Francisco Alvarez-Lerma
A1 Judith Marin
A1 Joan Ramon Masclans
A1 Davide Chiumello
A1 Angelo Pezzi
A1 Marcus Schultz
A1 Hafiz Mohamed
A1 Menno Van Der Eerden
A1 Roger A.S. Hoek
A1 D.A.M.P.J. Gommers
A1 Marta Di Pasquale
A1 Rok Civljak
A1 Marko Kutleša
A1 Matteo Bassetti
A1 George Dimopoulos
A1 Stefano Nava
A1 Fernando Rios
A1 Fernando G. Zampieri
A1 Pedro Povoa
A1 Lieuwe D. Bos
A1 Stefano Aliberti
A1 Antoni Torres
A1 Ignacio Martín-Loeches
A1 ,
YR 2017
UL http://openres.ersjournals.com/content/3/4/00092-2017.abstract
AB The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum of lower respiratory tract infections (LRTI), defined by specific epidemiological, clinical and microbiological aspects.A European network for ICU-related respiratory infections (ENIRRIs), supported by the European Respiratory Society, has been recently established, with the aim at studying all respiratory tract infective episodes except community-acquired ones. A multicentre, observational study is in progress, enrolling more than 1000 patients fulfilling the clinical, biochemical and radiological findings consistent with a LRTI. This article describes the methodology of this study. A specific interest is the clinical impact of non-ICU-acquired nosocomial pneumonia requiring ICU admission, non-ventilator-associated LRTIs occurring in the ICU, and ventilator-associated tracheobronchitis. The clinical meaning of microbiologically negative infectious episodes and specific details on antibiotic administration modalities, dosages and duration are also highlighted. Recently released guidelines address many unresolved questions which might be answered by such large-scale observational investigations. In light of the paucity of data regarding such topics, new interesting information is expected to be obtained from our network research activities, contributing to optimisation of care for critically ill patients in the ICU.Methodology for the first European network for ICU-related respiratory infections (ENIRRIs) project http://ow.ly/sud930fU1e7