RT Journal Article
SR Electronic
T1 Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP 00012-2018
DO 10.1183/23120541.00012-2018
VO 4
IS 2
A1 Marieke L. Duiverman
YR 2018
UL http://openres.ersjournals.com/content/4/2/00012-2018.abstract
AB Long-term noninvasive ventilation (NIV) to treat chronic hypercapnic respiratory failure is still controversial in severe chronic obstructive pulmonary disease (COPD) patients. However, with the introduction of high-intensity NIV, important benefits from this therapy have also been shown in COPD. In this review, the focus will be on the arguments for long-term NIV at home in patients with COPD. The rise of (high-intensity) NIV in COPD and the randomised controlled trials showing positive effects with this mode of ventilation will be discussed. Finally, the challenges that might be encountered (both in clinical practice and in research) in further optimising this therapy, monitoring and following patients, and selecting the patients who might benefit most will be reviewed.Adequately set chronic NIV improves outcomes in COPD patients with severe chronic hypercapnic respiratory failure http://ow.ly/slW230i8lck