RT Journal Article
SR Electronic
T1 Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study
JF ERJ Open Research
JO erjor
FD European Respiratory Society
SP 00096-2018
DO 10.1183/23120541.00096-2018
VO 4
IS 4
A1 Manuela Carugati
A1 Stefano Aliberti
A1 Luis Felipe Reyes
A1 Ricardo Franco Sadud
A1 Muhammad Irfan
A1 Cristina Prat
A1 Nilam J. Soni
A1 Paola Faverio
A1 Andrea Gori
A1 Francesco Blasi
A1 Marcos I. Restrepo
A1 ,
YR 2018
UL http://openres.ersjournals.com/content/4/4/00096-2018.abstract
AB This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines.This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015.In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01).Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations.Testing practices vary based on geography and disease severity, and IDSA/ATS/ERS testing recommendations are rarely followed http://ow.ly/80Iy30lxo1c