TY - JOUR T1 - From the pathophysiology of the human lung alveolus to epigenetic editing: Congress 2018 highlights from ERS Assembly 3 “Basic and Translational Science.” JF - ERJ Open Research JO - erjor DO - 10.1183/23120541.00194-2018 VL - 5 IS - 2 SP - 00194-2018 AU - Marko Z. Nikolić AU - Eva M. Garrido-Martin AU - Flavia R. Greiffo AU - Aurélie Fabre AU - Irene H. Heijink AU - Agnes Boots AU - Catherine M. Greene AU - Pieter S. Hiemstra AU - Sabine Bartel Y1 - 2019/04/01 UR - http://openres.ersjournals.com/content/5/2/00194-2018.abstract N2 - The European Respiratory Society (ERS) International Congress is the largest respiratory congress and brings together leading experts in all fields of respiratory medicine and research. ERS Assembly 3 shapes the basic and translational science aspects of this congress, aiming to combine cutting-edge novel developments in basic research with novel clinical findings. In this article, we summarise a selection of the scientific highlights from the perspective of the three groups within Assembly 3. In particular, we discuss new insights into the pathophysiology of the human alveolus, novel tools in organoid development and (epi)genome editing, as well as insights from the presented abstracts on novel therapeutic targets being identified for idiopathic pulmonary fibrosis.The amount of basic and translational science presented at #ERSCongress is steadily increasing, showing novel cutting-edge technologies and models. http://bit.ly/2GgXIJi ER -