PT - JOURNAL ARTICLE AU - Rishi J. Khusial AU - Persijn J. Honkoop AU - Victor van der Meer AU - Jiska B. Snoeck-Stroband AU - Jacob K. Sont TI - Validation of online Asthma Control Questionnaire and Asthma Quality of Life Questionnaire AID - 10.1183/23120541.00289-2019 DP - 2020 Jan 01 TA - ERJ Open Research PG - 00289-2019 VI - 6 IP - 1 4099 - http://openres.ersjournals.com/content/6/1/00289-2019.short 4100 - http://openres.ersjournals.com/content/6/1/00289-2019.full SO - erjor2020 Jan 01; 6 AB - Objective Several newly developed eHealth applications use online questionnaires to monitor asthma control. The Asthma Control Questionnaire (ACQ) and Asthma Quality of Life Questionnaire (AQLQ) are two such commonly used questionnaires. These questionnaires are validated for use on paper. This study aims to validate them by assessing the agreement between online and paper versions of the ACQ and AQLQ.Methods Patients (aged 18 years and older) from the Self-Management in Asthma Supported by Hospitals, ICT, Nurses and General Practitioners (SMASHING)-trial and Davos@home study were included in this study. Patients completed both the paper and online Dutch versions of the ACQ and AQLQ in a random order within a 2-week interval. Agreement between the different versions was assessed with paired t-tests, intraclass correlation coefficients and Bland–Altman plots.Results In total 44 patients were eligible for analysis. The mean difference between the paper and online versions of the ACQ was 0.04 (p=0.40) and for the AQLQ it was 0.08 (p=0.06). The intraclass correlation coefficient scores were 0.94 for the ACQ and 0.95 for the AQLQ.Conclusion The online versions of the ACQ and AQLQ show high levels of agreement with the paper versions and can therefore be safely used in eHealth applications to respectively monitor asthma control and quality of life.The self-administered online versions of the Asthma Control Questionnaire and Asthma Quality of Life Questionnaire show good agreement with the paper versions, and are therefore, valid measurement tools in eHealth applications http://bit.ly/2rGBbRf